Txnrd1 (thioredoxin reductase 1) - Rat Genome Database

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Gene: Txnrd1 (thioredoxin reductase 1) Heterocephalus glaber
Analyze
Symbol: Txnrd1
Name: thioredoxin reductase 1
RGD ID: 18934116
Description: ENCODES a protein that exhibits FAD binding (ortholog); identical protein binding (ortholog); mercury ion binding (ortholog); INVOLVED IN benzene-containing compound metabolic process (ortholog); cell population proliferation (ortholog); cellular oxidant detoxification (ortholog); ASSOCIATED WITH adenoma (ortholog); amyotrophic lateral sclerosis (ortholog); autism spectrum disorder (ortholog); FOUND IN cytoplasm (ortholog); fibrillar center (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: thioredoxin reductase 1, cytoplasmic
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247504,443,915 - 4,510,380 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247504,444,318 - 4,536,384 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Txnrd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247504,443,915 - 4,510,380 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247504,444,318 - 4,536,384 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TXNRD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812104,215,779 - 104,350,307 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12104,215,779 - 104,350,307 (+)EnsemblGRCh38hg38GRCh38
GRCh3712104,609,557 - 104,744,085 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612103,133,689 - 103,268,192 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412103,183,193 - 103,246,528NCBI
Celera12104,273,262 - 104,408,523 (+)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12101,669,268 - 101,804,294 (+)NCBIHuRef
CHM1_112104,575,396 - 104,709,877 (+)NCBICHM1_1
T2T-CHM13v2.012104,177,472 - 104,311,962 (+)NCBIT2T-CHM13v2.0
Txnrd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391082,669,785 - 82,733,558 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1082,669,785 - 82,733,546 (+)EnsemblGRCm39 Ensembl
GRCm381082,833,951 - 82,897,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1082,833,951 - 82,897,712 (+)EnsemblGRCm38mm10GRCm38
MGSCv371082,296,696 - 82,360,469 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361082,288,978 - 82,327,511 (+)NCBIMGSCv36mm8
Celera1084,818,861 - 84,882,466 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1040.66NCBI
Txnrd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8722,717,620 - 22,802,553 (-)NCBIGRCr8
mRatBN7.2720,830,042 - 20,914,990 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl720,830,045 - 20,907,863 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx722,794,109 - 22,878,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0724,956,878 - 25,041,383 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0724,733,893 - 24,818,472 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0726,946,124 - 26,984,400 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl726,946,125 - 26,984,400 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0727,065,819 - 27,104,095 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4723,055,544 - 23,093,815 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1723,075,818 - 23,112,858 (-)NCBI
Celera718,009,974 - 18,048,177 (-)NCBICelera
Cytogenetic Map7q13NCBI
Txnrd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540538,903,918 - 38,927,410 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540538,863,762 - 38,928,615 (+)NCBIChiLan1.0ChiLan1.0
TXNRD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210112,278,071 - 112,412,731 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112112,274,278 - 112,409,127 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012101,862,703 - 101,925,104 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112105,258,828 - 105,321,112 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12105,187,128 - 105,321,112 (+)Ensemblpanpan1.1panPan2
TXNRD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11033,904,065 - 34,021,549 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1033,886,343 - 34,021,696 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1033,824,269 - 33,941,521 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01034,747,423 - 34,864,919 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1034,747,416 - 34,864,924 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11034,482,294 - 34,599,587 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01034,765,845 - 34,883,396 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01034,960,435 - 35,077,894 (-)NCBIUU_Cfam_GSD_1.0
Txnrd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494517,175,082 - 17,233,863 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649210,187,206 - 10,225,989 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649210,185,096 - 10,244,466 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TXNRD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl580,172,260 - 80,236,219 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1580,170,334 - 80,213,889 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2583,657,828 - 83,701,655 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q2.3NCBI
TXNRD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11199,375,740 - 99,559,929 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1199,490,597 - 99,560,267 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037145,442,330 - 145,506,477 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000008961   ⟹   ENSHGLP00000008866
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247504,443,915 - 4,510,380 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000008962   ⟹   ENSHGLP00000008867
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247504,443,915 - 4,510,380 (-)Ensembl
RefSeq Acc Id: XM_013072257   ⟹   XP_012927711
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,536,384 (-)NCBI
RefSeq Acc Id: XM_013072258   ⟹   XP_012927712
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,475,016 (-)NCBI
RefSeq Acc Id: XM_013072259   ⟹   XP_012927713
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,490,717 (-)NCBI
RefSeq Acc Id: XM_013072260   ⟹   XP_012927714
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,489,791 (-)NCBI
RefSeq Acc Id: XM_021258387   ⟹   XP_021114046
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,490,718 (-)NCBI
RefSeq Acc Id: XM_021258388   ⟹   XP_021114047
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,490,718 (-)NCBI
RefSeq Acc Id: XM_021258389   ⟹   XP_021114048
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,475,412 (-)NCBI
RefSeq Acc Id: XM_021258390   ⟹   XP_021114049
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,490,718 (-)NCBI
RefSeq Acc Id: XM_021258391   ⟹   XP_021114050
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,475,413 (-)NCBI
RefSeq Acc Id: XM_021258392   ⟹   XP_021114051
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247504,444,318 - 4,490,718 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_012927711   ⟸   XM_013072257
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021114051   ⟸   XM_021258392
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021114046   ⟸   XM_021258387
- Peptide Label: isoform X1
- UniProtKB: G5AR46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114049   ⟸   XM_021258390
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021114047   ⟸   XM_021258388
- Peptide Label: isoform X1
- UniProtKB: G5AR46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012927713   ⟸   XM_013072259
- Peptide Label: isoform X2
RefSeq Acc Id: XP_012927714   ⟸   XM_013072260
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021114050   ⟸   XM_021258391
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021114048   ⟸   XM_021258389
- Peptide Label: isoform X2
RefSeq Acc Id: XP_012927712   ⟸   XM_013072258
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000008867   ⟸   ENSHGLT00000008962
RefSeq Acc Id: ENSHGLP00000008866   ⟸   ENSHGLT00000008961


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006372 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000008962 ENTREZGENE
Gene3D-CATH 3.30.390.30 UniProtKB/TrEMBL
  FAD/NAD(P)-binding domain UniProtKB/TrEMBL
InterPro FAD/NAD-bd_sf UniProtKB/TrEMBL
  FAD/NAD-binding_dom UniProtKB/TrEMBL
  FAD/NAD-linked_Rdtase_dimer_sf UniProtKB/TrEMBL
  GSHR/TRXR-like UniProtKB/TrEMBL
  Pyr_nuc-diS_OxRdtase UniProtKB/TrEMBL
  Pyr_nucl-diS_OxRdtase_dimer UniProtKB/TrEMBL
  Pyr_OxRdtase_I_AS UniProtKB/TrEMBL
  Thioredoxin/glutathione_Rdtase UniProtKB/TrEMBL
NCBI Gene Txnrd1 ENTREZGENE
PANTHER GLUTATHIONE REDUCTASE UniProtKB/TrEMBL
  THIOREDOXIN REDUCTASE 1 UniProtKB/TrEMBL
Pfam Pyr_redox_2 UniProtKB/TrEMBL
  Pyr_redox_dim UniProtKB/TrEMBL
PIRSF Mercury_reductase_MerA UniProtKB/TrEMBL
PRINTS FADPNR UniProtKB/TrEMBL
  PNDRDTASEI UniProtKB/TrEMBL
PROSITE PYRIDINE_REDOX_1 UniProtKB/TrEMBL
Superfamily-SCOP FAD/NAD(P)-binding domain UniProtKB/TrEMBL
  FAD/NAD-linked reductases, dimerisation (C-terminal) domain UniProtKB/TrEMBL
UniProt G5AR46 ENTREZGENE, UniProtKB/TrEMBL