Thap2 (THAP domain containing 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Thap2 (THAP domain containing 2) Heterocephalus glaber
Analyze
Symbol: Thap2
Name: THAP domain containing 2
RGD ID: 18933619
Description: ENCODES a protein that exhibits DNA binding (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: THAP domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475026,085,638 - 26,097,815 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475026,086,472 - 26,098,303 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (ISO)
nucleus  (IEA)

Molecular Function
DNA binding  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Thap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475026,085,638 - 26,097,815 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475026,086,472 - 26,098,303 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
THAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381271,664,301 - 71,680,644 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1271,664,301 - 71,680,644 (+)EnsemblGRCh38hg38GRCh38
GRCh371272,058,081 - 72,074,424 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361270,344,051 - 70,360,686 (+)NCBINCBI36Build 36hg18NCBI36
Celera1271,720,131 - 71,736,767 (+)NCBICelera
Cytogenetic Map12q21.1NCBI
HuRef1269,106,790 - 69,123,547 (+)NCBIHuRef
CHM1_11272,024,918 - 72,041,669 (+)NCBICHM1_1
T2T-CHM13v2.01271,641,810 - 71,658,153 (+)NCBIT2T-CHM13v2.0
Thap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910115,204,303 - 115,220,340 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10115,204,309 - 115,220,348 (-)EnsemblGRCm39 Ensembl
GRCm3810115,368,398 - 115,384,435 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10115,368,404 - 115,384,443 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710114,807,022 - 114,821,491 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610114,774,076 - 114,788,545 (-)NCBIMGSCv36mm8
Celera10117,299,363 - 117,313,938 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1063.51NCBI
Thap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8752,879,011 - 52,893,680 (-)NCBIGRCr8
mRatBN7.2750,992,912 - 51,007,582 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl750,995,793 - 51,008,061 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx752,899,683 - 52,914,352 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0755,102,766 - 55,117,437 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0754,880,756 - 54,895,421 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0758,350,744 - 58,365,812 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl758,354,582 - 58,365,313 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0758,359,646 - 58,374,231 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4754,644,248 - 54,655,301 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera747,784,948 - 47,800,212 (-)NCBICelera
Cytogenetic Map7q22NCBI
Thap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540511,647,989 - 11,665,110 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540511,647,989 - 11,665,110 (+)NCBIChiLan1.0ChiLan1.0
THAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21079,692,855 - 79,709,563 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11279,689,334 - 79,707,461 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01269,187,221 - 69,204,095 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11272,046,980 - 72,063,734 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1272,046,980 - 72,063,734 (+)Ensemblpanpan1.1panPan2
THAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11013,216,886 - 13,231,548 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1013,155,478 - 13,170,350 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01013,351,032 - 13,365,909 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1013,351,264 - 13,363,007 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11013,214,624 - 13,229,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01013,462,189 - 13,477,047 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01013,585,921 - 13,600,811 (+)NCBIUU_Cfam_GSD_1.0
THAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl535,671,280 - 35,687,288 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1535,671,280 - 35,687,298 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2538,373,033 - 38,388,509 (+)NCBISscrofa10.2Sscrofa10.2susScr3
THAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11167,279,973 - 67,296,919 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1167,280,586 - 67,296,919 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037178,357,736 - 178,374,585 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004845033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01031147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000017746   ⟹   ENSHGLP00000017571
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475026,085,638 - 26,097,815 (-)Ensembl
RefSeq Acc Id: XM_004845033   ⟹   XP_004845090
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475026,086,472 - 26,098,303 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004845090 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017571
Reference Protein Sequences
RefSeq Acc Id: XP_004845090   ⟸   XM_004845033
- UniProtKB: G5BSY2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000017571   ⟸   ENSHGLT00000017746


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012573 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000017746 ENTREZGENE
Gene3D-CATH THAP domain UniProtKB/TrEMBL
InterPro THAP_Znf UniProtKB/TrEMBL
  THAP_Znf_sf UniProtKB/TrEMBL
NCBI Gene Thap2 ENTREZGENE
PANTHER THAP DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  THAP DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam THAP UniProtKB/TrEMBL
PROSITE ZF_THAP UniProtKB/TrEMBL
SMART DM3 UniProtKB/TrEMBL
  THAP UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt G5BSY2 ENTREZGENE, UniProtKB/TrEMBL