Cyfip1 (cytoplasmic FMR1 interacting protein 1) - Rat Genome Database

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Gene: Cyfip1 (cytoplasmic FMR1 interacting protein 1) Heterocephalus glaber
Analyze
Symbol: Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
RGD ID: 18933184
Description: ENCODES a protein that exhibits RNA 7-methylguanosine cap binding (ortholog); small GTPase binding (ortholog); translation repressor activity (ortholog); INVOLVED IN axon extension (ortholog); cellular response to insulin stimulus (ortholog); cognition (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rho/Rac/Cdc42 mediated signaling pathway; ASSOCIATED WITH Angelman syndrome (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN axonal growth cone (ortholog); central region of growth cone (ortholog); dendritic growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytoplasmic FMR1-interacting protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248962,723,462 - 2,800,113 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248962,726,622 - 2,774,671 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cyfip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248962,723,462 - 2,800,113 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248962,726,622 - 2,774,671 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CYFIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381522,867,052 - 22,980,898 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1522,867,052 - 22,981,063 (-)EnsemblGRCh38hg38GRCh38
GRCh371522,892,170 - 23,006,016 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361520,444,125 - 20,555,044 (+)NCBINCBI36Build 36hg18NCBI36
Build 341520,444,124 - 20,555,043NCBI
Celera151,376,209 - 1,487,232 (-)NCBICelera
Cytogenetic Map15q11.2NCBI
HuRef151,205,387 - 1,315,987 (+)NCBIHuRef
CHM1_11522,841,725 - 22,952,892 (+)NCBICHM1_1
T2T-CHM13v2.01520,538,904 - 20,652,761 (-)NCBIT2T-CHM13v2.0
Cyfip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39755,491,556 - 55,582,381 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl755,491,493 - 55,582,350 (+)EnsemblGRCm39 Ensembl
GRCm38755,842,022 - 55,932,633 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl755,841,745 - 55,932,602 (+)EnsemblGRCm38mm10GRCm38
MGSCv37763,097,441 - 63,188,003 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36755,739,875 - 55,798,505 (+)NCBIMGSCv36mm8
Celera753,195,732 - 53,286,248 (+)NCBICelera
Cytogenetic Map7B5NCBI
cM Map733.42NCBI
Cyfip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81115,842,754 - 115,935,163 (+)NCBIGRCr8
mRatBN7.21106,710,924 - 106,799,393 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1106,711,016 - 106,799,386 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1112,100,298 - 112,189,006 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01120,572,167 - 120,660,875 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01113,821,095 - 113,909,828 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01114,258,773 - 114,347,138 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1114,258,719 - 114,347,137 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01115,265,128 - 115,353,515 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41107,245,993 - 107,334,337 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11107,324,324 - 107,412,679 (+)NCBI
Celera1100,921,447 - 101,009,775 (+)NCBICelera
Cytogenetic Map1q22NCBI
CYFIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21612,204,434 - 12,315,794 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11515,928,676 - 16,042,452 (-)NCBINHGRI_mPanPan1
PanPan1.11520,462,755 - 20,573,684 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1520,462,811 - 20,573,684 (+)Ensemblpanpan1.1panPan2
CYFIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1332,096,471 - 32,170,107 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl332,097,037 - 32,187,781 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha334,509,239 - 34,585,945 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0332,162,887 - 32,239,605 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl332,117,281 - 32,240,269 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1331,650,943 - 31,773,999 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0331,945,859 - 32,022,546 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0332,056,552 - 32,133,289 (+)NCBIUU_Cfam_GSD_1.0
Cyfip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640120,416,388 - 120,482,622 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647138,267,703 - 38,332,218 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647138,264,455 - 38,331,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYFIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1532,064,475 - 32,175,094 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11532,064,431 - 32,175,095 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CYFIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12653,562,105 - 53,673,544 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2653,595,767 - 53,672,977 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605436,289,010 - 36,405,036 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000011858   ⟹   ENSHGLP00000011730
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248962,723,462 - 2,800,113 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000011859   ⟹   ENSHGLP00000011731
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248962,726,622 - 2,800,113 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000011860   ⟹   ENSHGLP00000011732
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248962,727,157 - 2,774,670 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000011861   ⟹   ENSHGLP00000011733
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248962,732,014 - 2,774,670 (-)Ensembl
RefSeq Acc Id: XM_021250149   ⟹   XP_021105808
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248962,726,622 - 2,774,671 (-)NCBI
RefSeq Acc Id: XM_021250151   ⟹   XP_021105810
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248962,726,622 - 2,774,671 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021105808 (Get FASTA)   NCBI Sequence Viewer  
  XP_021105810 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011730
  ENSHGLP00000011731
Reference Protein Sequences
RefSeq Acc Id: XP_021105808   ⟸   XM_021250149
- Peptide Label: isoform X1
- UniProtKB: G5AZH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021105810   ⟸   XM_021250151
- Peptide Label: isoform X2
- UniProtKB: G5AZH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000011730   ⟸   ENSHGLT00000011858
RefSeq Acc Id: ENSHGLP00000011731   ⟸   ENSHGLT00000011859
RefSeq Acc Id: ENSHGLP00000011733   ⟸   ENSHGLT00000011861
RefSeq Acc Id: ENSHGLP00000011732   ⟸   ENSHGLT00000011860


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008409 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011858 ENTREZGENE
  ENSHGLT00000011859 ENTREZGENE
InterPro CYRIA/CYRIB_Rac1-bd UniProtKB/TrEMBL
  Cytoplasmic_FMR1-int UniProtKB/TrEMBL
NCBI Gene Cyfip1 ENTREZGENE
PANTHER CYTOPLASMIC FMR1-INTERACTING PROTEIN 1 UniProtKB/TrEMBL
  CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED UniProtKB/TrEMBL
Pfam CYRIA-B_Rac1-bd UniProtKB/TrEMBL
  FragX_IP UniProtKB/TrEMBL
PIRSF FMR1_interacting UniProtKB/TrEMBL
PRINTS CYTOFMRPINTP UniProtKB/TrEMBL
UniProt G5AZH3 ENTREZGENE, UniProtKB/TrEMBL