Zranb3 (zinc finger RANBP2-type containing 3) - Rat Genome Database

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Gene: Zranb3 (zinc finger RANBP2-type containing 3) Heterocephalus glaber
Analyze
Symbol: Zranb3
Name: zinc finger RANBP2-type containing 3
RGD ID: 18932858
Description: ENCODES a protein that exhibits ATP-dependent DNA/DNA annealing activity (ortholog); DNA endonuclease activity (ortholog); DNA helicase activity (ortholog); INVOLVED IN DNA damage response (ortholog); DNA rewinding (ortholog); negative regulation of DNA recombination (ortholog); ASSOCIATED WITH genetic disease (ortholog); WHIM syndrome 1 (ortholog); FOUND IN nuclear replication fork (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA annealing helicase and endonuclease ZRANB3; Zinc finger Ran-binding domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473234,556,784 - 34,848,965 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473234,561,249 - 34,848,093 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Zranb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473234,556,784 - 34,848,965 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473234,561,249 - 34,848,093 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ZRANB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382135,196,969 - 135,531,218 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2135,136,916 - 135,531,218 (-)EnsemblGRCh38hg38GRCh38
GRCh372135,954,539 - 136,288,788 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362135,674,041 - 136,005,276 (-)NCBINCBI36Build 36hg18NCBI36
Build 342135,728,218 - 135,830,163NCBI
Celera2129,670,506 - 129,999,572 (-)NCBICelera
Cytogenetic Map2q21.3NCBI
HuRef2127,950,131 - 128,281,480 (-)NCBIHuRef
CHM1_12135,962,511 - 136,293,706 (-)NCBICHM1_1
T2T-CHM13v2.02135,637,447 - 135,971,741 (-)NCBIT2T-CHM13v2.0
Zranb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391127,881,916 - 128,030,799 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1127,881,921 - 128,030,784 (-)EnsemblGRCm39 Ensembl
GRCm381127,954,179 - 128,103,053 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1127,954,184 - 128,103,047 (-)EnsemblGRCm38mm10GRCm38
MGSCv371129,850,763 - 129,998,985 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,781,725 - 129,930,593 (-)NCBIMGSCv36mm8
Celera1130,582,923 - 130,729,435 (-)NCBICelera
Cytogenetic Map1E3NCBI
cM Map155.8NCBI
Zranb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81341,993,110 - 42,148,298 (-)NCBIGRCr8
mRatBN7.21339,440,653 - 39,595,782 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1339,440,889 - 39,595,670 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01344,661,375 - 44,812,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,661,398 - 44,798,543 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01349,745,984 - 49,897,700 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41340,648,221 - 40,803,738 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1339,815,144 - 39,969,876 (-)NCBICelera
Cytogenetic Map13q13NCBI
Zranb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554402,680,787 - 2,888,345 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554402,683,041 - 2,907,859 (-)NCBIChiLan1.0ChiLan1.0
ZRANB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21339,400,603 - 39,755,767 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B39,415,302 - 39,770,737 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B24,331,731 - 24,665,652 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B139,271,306 - 139,603,946 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B139,234,909 - 139,577,193 (-)Ensemblpanpan1.1panPan2
ZRANB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11938,003,273 - 38,302,598 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1937,957,421 - 38,301,888 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1938,247,332 - 38,546,267 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01939,448,903 - 39,748,462 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1939,447,977 - 39,747,839 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11938,091,050 - 38,390,605 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01938,251,868 - 38,553,727 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01939,487,157 - 39,786,272 (-)NCBIUU_Cfam_GSD_1.0
Zranb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303101,057,646 - 101,288,879 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646940,328,787 - 40,609,533 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646940,328,850 - 40,558,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZRANB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1516,414,757 - 16,727,841 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11516,414,291 - 16,727,659 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21519,093,163 - 19,182,218 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZRANB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11019,428,139 - 19,739,886 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1019,427,652 - 19,572,384 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660612,724,205 - 3,069,554 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013076896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013076899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021236942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021236951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021236962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01006946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01006964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01004167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH166011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000022611   ⟹   ENSHGLP00000022399
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473234,556,784 - 34,848,965 (-)Ensembl
RefSeq Acc Id: XM_013076896   ⟹   XP_012932350
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473234,561,249 - 34,848,093 (-)NCBI
RefSeq Acc Id: XM_013076899   ⟹   XP_012932353
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473234,621,578 - 34,848,093 (-)NCBI
RefSeq Acc Id: XM_021236942   ⟹   XP_021092601
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473234,621,578 - 34,848,093 (-)NCBI
RefSeq Acc Id: XM_021236951   ⟹   XP_021092610
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473234,621,578 - 34,847,489 (-)NCBI
RefSeq Acc Id: XM_021236962   ⟹   XP_021092621
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473234,621,578 - 34,848,093 (-)NCBI
Protein Sequences
Protein RefSeqs XP_012932350 (Get FASTA)   NCBI Sequence Viewer  
  XP_012932353 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092601 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092610 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092621 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA98293 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022399
GenBank Protein JAN99465 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_012932350   ⟸   XM_013076896
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JVE0 (UniProtKB/TrEMBL),   G5AMN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012932353   ⟸   XM_013076899
- Peptide Label: isoform X3
- UniProtKB: G5AMN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092621   ⟸   XM_021236962
- Peptide Label: isoform X2
- UniProtKB: G5AMN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092601   ⟸   XM_021236942
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JVE0 (UniProtKB/TrEMBL),   G5AMN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092610   ⟸   XM_021236951
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JVE0 (UniProtKB/TrEMBL),   G5AMN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000022399   ⟸   ENSHGLT00000022611


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015976 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022611 ENTREZGENE
Gene3D-CATH 1.10.30.50 UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  Zn-finger domain of Sec23/24 UniProtKB/TrEMBL
InterPro Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  HNH UniProtKB/TrEMBL
  HNH_nuc UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
KEGG Report hgl:101726197 UniProtKB/TrEMBL
NCBI Gene Zranb3 ENTREZGENE
PANTHER DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 UniProtKB/TrEMBL
  DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER UniProtKB/TrEMBL
Pfam Helicase_C UniProtKB/TrEMBL
  HNH UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
  HNHc UniProtKB/TrEMBL
  ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90209 UniProtKB/TrEMBL
UniProt A0A0P6JVE0 ENTREZGENE, UniProtKB/TrEMBL
  G5AMN3 ENTREZGENE, UniProtKB/TrEMBL