Puf60 (poly(U) binding splicing factor 60) - Rat Genome Database

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Gene: Puf60 (poly(U) binding splicing factor 60) Heterocephalus glaber
Analyze
Symbol: Puf60
Name: poly(U) binding splicing factor 60
RGD ID: 18932478
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (inferred); mRNA processing (inferred); mRNA splice site recognition (inferred); ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 2 (ortholog); CHARGE syndrome (ortholog); epidermolysis bullosa simplex with muscular dystrophy (ortholog); FOUND IN cell junction (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly(U)-binding-splicing factor PUF60
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,983,111 - 12,996,576 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,983,106 - 12,996,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Puf60
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,983,111 - 12,996,576 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,983,106 - 12,996,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PUF60
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,816,344 - 143,829,315 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8143,816,344 - 143,830,709 (-)EnsemblGRCh38hg38GRCh38
GRCh378144,898,514 - 144,911,485 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,970,535 - 144,983,525 (-)NCBINCBI36Build 36hg18NCBI36
Build 348144,970,535 - 144,983,525NCBI
Celera8141,211,452 - 141,224,560 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,151,474 - 140,164,519 (-)NCBIHuRef
CHM1_18144,938,756 - 144,951,801 (-)NCBICHM1_1
T2T-CHM13v2.08144,973,042 - 144,986,016 (-)NCBIT2T-CHM13v2.0
Puf60
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,942,031 - 75,954,386 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1575,942,031 - 75,952,773 (-)EnsemblGRCm39 Ensembl
GRCm381576,070,182 - 76,082,537 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,070,182 - 76,080,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv371575,900,612 - 75,911,376 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361575,897,439 - 75,908,167 (-)NCBIMGSCv36mm8
Celera1577,571,109 - 77,581,873 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.32NCBI
Puf60
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,663,490 - 109,674,443 (-)NCBIGRCr8
mRatBN7.27107,782,799 - 107,793,759 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7107,782,770 - 107,794,531 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,523,205 - 109,534,132 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07111,746,882 - 111,757,809 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07111,703,620 - 111,714,562 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,129,237 - 117,140,234 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,129,237 - 117,140,214 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,114,908 - 117,125,972 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,101,160 - 114,112,091 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,135,433 - 114,146,350 (-)NCBI
Celera7104,139,368 - 104,150,299 (-)NCBICelera
Cytogenetic Map7q34NCBI
Puf60
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,482,968 - 2,497,339 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,482,968 - 2,497,339 (-)NCBIChiLan1.0ChiLan1.0
PUF60
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,302,359 - 161,315,435 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18136,819,615 - 136,833,130 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08140,571,688 - 140,584,778 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18143,583,451 - 143,597,351 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8143,583,451 - 143,597,399 (-)Ensemblpanpan1.1panPan2
PUF60
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,375,781 - 37,387,969 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,375,651 - 37,387,875 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,332,030 - 37,344,218 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,847,479 - 37,859,669 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,847,344 - 37,859,609 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,521,566 - 37,533,753 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,638,507 - 37,650,690 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,119,856 - 38,132,044 (-)NCBIUU_Cfam_GSD_1.0
Puf60
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303909,405 - 922,238 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364708,336,390 - 8,348,609 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364708,336,852 - 8,348,335 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PUF60
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4812,131 - 824,318 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14812,137 - 824,321 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PUF60
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,034,526 - 138,047,485 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,034,395 - 138,042,468 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,829,905 - 1,842,943 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000008542   ⟹   ENSHGLP00000008452
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473512,983,111 - 12,996,576 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000008543   ⟹   ENSHGLP00000008453
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473512,983,111 - 12,996,576 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000008544   ⟹   ENSHGLP00000008454
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473512,987,843 - 12,996,430 (+)Ensembl
RefSeq Acc Id: XM_004837793   ⟹   XP_004837850
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473512,983,106 - 12,996,578 (+)NCBI
RefSeq Acc Id: XM_004837794   ⟹   XP_004837851
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473512,983,106 - 12,996,578 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004837850 (Get FASTA)   NCBI Sequence Viewer  
  XP_004837851 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008452
  ENSHGLP00000008453
  ENSHGLP00100036064
Reference Protein Sequences
RefSeq Acc Id: XP_004837850   ⟸   XM_004837793
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JIK7 (UniProtKB/TrEMBL),   G5AWE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004837851   ⟸   XM_004837794
- Peptide Label: isoform X2
- UniProtKB: G5AWE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000008454   ⟸   ENSHGLT00000008544
RefSeq Acc Id: ENSHGLP00000008452   ⟸   ENSHGLT00000008542
RefSeq Acc Id: ENSHGLP00000008453   ⟸   ENSHGLT00000008543


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006111 Ensembl, ENTREZGENE
  ENSHGLG00100012362 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000008542 ENTREZGENE
  ENSHGLT00000008543 ENTREZGENE
  ENSHGLT00100081316 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  PUF60-like UniProtKB/TrEMBL
  PUF60_RRM1 UniProtKB/TrEMBL
  PUF60_RRM2 UniProtKB/TrEMBL
  PUF60_RRM3 UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  RRM_dom_euk UniProtKB/TrEMBL
KEGG Report hgl:101711469 UniProtKB/TrEMBL
NCBI Gene Puf60 ENTREZGENE
PANTHER POLY(U)-BINDING-SPLICING FACTOR PUF60 UniProtKB/TrEMBL
  POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A0P6JIK7 ENTREZGENE, UniProtKB/TrEMBL
  G5AWE4 ENTREZGENE, UniProtKB/TrEMBL