Tor2a (torsin family 2 member A) - Rat Genome Database

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Gene: Tor2a (torsin family 2 member A) Heterocephalus glaber
Analyze
Symbol: Tor2a
Name: torsin family 2 member A
RGD ID: 18932125
Description: ENCODES a protein that exhibits hormone activity (ortholog); INVOLVED IN cell-cell signaling (ortholog); positive regulation of calcium ion transmembrane transport (ortholog); positive regulation of cAMP-mediated signaling (ortholog); ASSOCIATED WITH congenital disorder of glycosylation Iu (ortholog); developmental and epileptic encephalopathy (ortholog); developmental and epileptic encephalopathy 31A (ortholog); FOUND IN extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: prosalusin; Torsin-2A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,802,300 - 7,806,239 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,802,202 - 7,806,235 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tor2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,802,300 - 7,806,239 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,802,202 - 7,806,235 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TOR2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,731,524 - 127,735,294 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,731,524 - 127,735,313 (-)EnsemblGRCh38hg38GRCh38
GRCh379130,493,803 - 130,497,573 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,533,624 - 129,537,425 (-)NCBINCBI36Build 36hg18NCBI36
Build 349127,573,357 - 127,577,111NCBI
Celera9101,144,673 - 101,148,474 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,110,338 - 100,114,163 (-)NCBIHuRef
CHM1_19130,644,952 - 130,648,777 (-)NCBICHM1_1
T2T-CHM13v2.09139,938,968 - 139,942,738 (-)NCBIT2T-CHM13v2.0
Tor2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,647,289 - 32,652,256 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,647,246 - 32,652,256 (+)EnsemblGRCm39 Ensembl
GRCm38232,757,234 - 32,762,250 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,757,234 - 32,762,244 (+)EnsemblGRCm38mm10GRCm38
MGSCv37232,612,791 - 32,617,764 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,579,280 - 32,584,253 (+)NCBIMGSCv36mm8
Celera232,464,012 - 32,469,100 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Tor2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,446,260 - 36,450,339 (+)NCBIGRCr8
mRatBN7.2316,048,591 - 16,053,198 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl316,048,549 - 16,052,634 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx319,116,791 - 19,120,857 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,701,796 - 27,705,862 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,953,643 - 25,957,709 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,794,731 - 11,800,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,795,629 - 11,799,693 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0317,132,371 - 17,136,665 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,733,950 - 11,738,016 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,630,321 - 11,634,386 (+)NCBI
Celera310,788,141 - 10,792,207 (+)NCBICelera
Cytogenetic Map3p11NCBI
Tor2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419922,901 - 926,624 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955419922,901 - 926,624 (+)NCBIChiLan1.0ChiLan1.0
TOR2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,619,313 - 11,623,306 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,621,660 - 11,625,653 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,851,255 - 98,855,086 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,523,547 - 127,527,452 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,523,547 - 127,527,403 (-)Ensemblpanpan1.1panPan2
TOR2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,658,006 - 55,662,181 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,658,192 - 55,662,047 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,851,506 - 54,855,465 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,579,502 - 56,583,704 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,579,686 - 56,585,382 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,339,751 - 55,343,947 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,654,459 - 55,658,654 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,745,704 - 55,749,899 (+)NCBIUU_Cfam_GSD_1.0
Tor2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,636,568 - 195,640,448 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,404,065 - 15,408,997 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,405,089 - 15,408,971 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOR2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,233,110 - 268,237,458 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,233,103 - 268,237,478 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,125,770 - 302,128,299 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TOR2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,397,539 - 10,401,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,397,613 - 10,400,839 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,819,722 - 5,823,582 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000027272   ⟹   ENSHGLP00000027032
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247607,802,300 - 7,806,239 (+)Ensembl
RefSeq Acc Id: XM_004849319   ⟹   XP_004849376
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247607,802,215 - 7,806,235 (+)NCBI
RefSeq Acc Id: XM_013073783   ⟹   XP_012929237
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247607,802,773 - 7,806,235 (+)NCBI
RefSeq Acc Id: XM_021262001   ⟹   XP_021117660
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247607,802,211 - 7,806,235 (+)NCBI
RefSeq Acc Id: XM_021262002   ⟹   XP_021117661
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247607,802,202 - 7,806,235 (+)NCBI
RefSeq Acc Id: XM_021262003   ⟹   XP_021117662
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247607,802,207 - 7,806,235 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004849376 (Get FASTA)   NCBI Sequence Viewer  
  XP_012929237 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117660 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117661 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117662 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10127 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027032
GenBank Protein JAN99771 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021117661   ⟸   XM_021262002
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021117662   ⟸   XM_021262003
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021117660   ⟸   XM_021262001
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004849376   ⟸   XM_004849319
- Peptide Label: isoform X3
- UniProtKB: G5BLG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012929237   ⟸   XM_013073783
- Peptide Label: isoform X5
RefSeq Acc Id: ENSHGLP00000027032   ⟸   ENSHGLT00000027272


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019225 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000027272 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ClpA/B UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  TOR1A_C UniProtKB/TrEMBL
  Torsin UniProtKB/TrEMBL
  Torsin_1/2 UniProtKB/TrEMBL
KEGG Report hgl:101726025 UniProtKB/TrEMBL
NCBI Gene Tor2a ENTREZGENE
PANTHER PTHR10760 UniProtKB/TrEMBL
  TORSIN-2A UniProtKB/TrEMBL
Pfam TOR1A_C UniProtKB/TrEMBL
  Torsin UniProtKB/TrEMBL
PIRSF Torsin_2A UniProtKB/TrEMBL
PRINTS CLPPROTEASEA UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt G5BLG6 ENTREZGENE, UniProtKB/TrEMBL