Epb41 (erythrocyte membrane protein band 4.1) - Rat Genome Database

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Gene: Epb41 (erythrocyte membrane protein band 4.1) Heterocephalus glaber
Analyze
Symbol: Epb41
Name: erythrocyte membrane protein band 4.1
RGD ID: 18932101
Description: ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog); actin binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN positive regulation of protein localization to cell cortex (ortholog); protein-containing complex assembly (ortholog); regulation of calcium ion transport (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH Elliptocytosis 1 (ortholog); genetic disease (ortholog); hemolytic anemia (ortholog); FOUND IN basolateral plasma membrane (ortholog); cell junction (ortholog); cortical cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); protein 4.1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476412,770,814 - 12,892,540 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476412,692,114 - 12,896,252 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Epb41
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476412,770,814 - 12,892,540 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476412,692,114 - 12,896,252 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EPB41
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,887,100 - 29,120,041 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,887,091 - 29,120,046 (+)EnsemblGRCh38hg38GRCh38
GRCh37129,213,612 - 29,446,553 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36129,086,215 - 29,319,545 (+)NCBINCBI36Build 36hg18NCBI36
Celera127,609,687 - 27,842,706 (+)NCBICelera
Cytogenetic Map1p35.3NCBI
HuRef127,466,104 - 27,698,673 (+)NCBIHuRef
CHM1_1129,328,966 - 29,561,931 (+)NCBICHM1_1
T2T-CHM13v2.0128,729,007 - 28,962,697 (+)NCBIT2T-CHM13v2.0
Epb41
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394131,650,724 - 131,802,824 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4131,650,724 - 131,802,632 (-)EnsemblGRCm39 Ensembl
GRCm384131,923,413 - 132,075,346 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4131,923,413 - 132,075,321 (-)EnsemblGRCm38mm10GRCm38
MGSCv374131,479,328 - 131,631,228 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364131,196,360 - 131,344,173 (-)NCBIMGSCv36mm8
Celera4130,083,954 - 130,236,196 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map464.54NCBI
Epb41
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85149,394,080 - 149,548,178 (-)NCBIGRCr8
mRatBN7.25144,110,010 - 144,264,037 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5144,111,906 - 144,237,821 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5146,815,209 - 146,943,098 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05148,585,056 - 148,712,944 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05148,573,947 - 148,701,609 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05150,081,727 - 150,243,186 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5150,084,611 - 150,167,077 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05153,760,449 - 153,919,840 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45150,782,245 - 150,908,888 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5142,553,286 - 142,705,904 (-)NCBICelera
Cytogenetic Map5q36NCBI
Epb41
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554528,009,194 - 8,124,713 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554527,930,095 - 8,123,165 (+)NCBIChiLan1.0ChiLan1.0
EPB41
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21197,723,248 - 197,954,984 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11196,842,522 - 197,047,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,158,807 - 28,390,541 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1129,186,202 - 29,416,495 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl129,284,923 - 29,416,474 (+)Ensemblpanpan1.1panPan2
EPB41
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,474,916 - 71,673,052 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,474,954 - 71,584,266 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha268,051,718 - 68,160,301 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0272,034,545 - 72,232,624 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl272,032,484 - 72,212,785 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1268,864,384 - 68,973,060 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0269,871,948 - 69,980,550 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0270,869,968 - 70,978,583 (-)NCBIUU_Cfam_GSD_1.0
Epb41
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505847,092,095 - 47,265,131 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647412,991,737 - 13,090,615 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647412,917,009 - 13,090,640 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPB41
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl685,865,277 - 86,029,508 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1685,842,538 - 86,029,522 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2679,809,404 - 79,916,611 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EPB41
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120103,704,322 - 103,928,004 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20103,699,694 - 103,927,730 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603312,597,213 - 12,828,450 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013074228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021263223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01044833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01044843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000017115   ⟹   ENSHGLP00000016944
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476412,770,814 - 12,892,540 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000017116   ⟹   ENSHGLP00000016945
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476412,781,890 - 12,892,540 (+)Ensembl
RefSeq Acc Id: XM_013074228   ⟹   XP_012929682
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,186 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263211   ⟹   XP_021118870
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,186 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263212   ⟹   XP_021118871
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,711,669 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263213   ⟹   XP_021118872
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,187 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263214   ⟹   XP_021118873
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,187 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263215   ⟹   XP_021118874
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,188 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263216   ⟹   XP_021118875
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,189 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263217   ⟹   XP_021118876
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,190 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263218   ⟹   XP_021118877
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,190 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263219   ⟹   XP_021118878
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,192 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263220   ⟹   XP_021118879
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,114 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263221   ⟹   XP_021118880
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,193 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263222   ⟹   XP_021118881
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,194 - 12,896,252 (+)NCBI
RefSeq Acc Id: XM_021263223   ⟹   XP_021118882
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476412,692,196 - 12,896,252 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021118879   ⟸   XM_021263220
- Peptide Label: isoform X11
RefSeq Acc Id: XP_012929682   ⟸   XM_013074228
- Peptide Label: isoform X1
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118870   ⟸   XM_021263211
- Peptide Label: isoform X2
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118873   ⟸   XM_021263214
- Peptide Label: isoform X5
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118872   ⟸   XM_021263213
- Peptide Label: isoform X4
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118874   ⟸   XM_021263215
- Peptide Label: isoform X6
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118875   ⟸   XM_021263216
- Peptide Label: isoform X7
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118876   ⟸   XM_021263217
- Peptide Label: isoform X8
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118877   ⟸   XM_021263218
- Peptide Label: isoform X9
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118878   ⟸   XM_021263219
- Peptide Label: isoform X10
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118880   ⟸   XM_021263221
- Peptide Label: isoform X12
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118881   ⟸   XM_021263222
- Peptide Label: isoform X13
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118882   ⟸   XM_021263223
- Peptide Label: isoform X14
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118871   ⟸   XM_021263212
- Peptide Label: isoform X3
- UniProtKB: G5AP97 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000016944   ⟸   ENSHGLT00000017115
RefSeq Acc Id: ENSHGLP00000016945   ⟸   ENSHGLT00000017116


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012118 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000017115 ENTREZGENE
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) UniProtKB/TrEMBL
InterPro Band_4.1_C UniProtKB/TrEMBL
  Band_41_domain UniProtKB/TrEMBL
  EPB4.1_FERM_F1 UniProtKB/TrEMBL
  Ez/rad/moesin-like UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_CS UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  FERM_PH-like_C UniProtKB/TrEMBL
  IPR014847 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  SAB_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene Epb41 ENTREZGENE
PANTHER 4.1 G PROTEIN UniProtKB/TrEMBL
  PROTEIN 4.1 UniProtKB/TrEMBL
Pfam 4_1_CTD UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  PF08736 UniProtKB/TrEMBL
  SAB UniProtKB/TrEMBL
PIRSF Membrane_skeletal_4_1 UniProtKB/TrEMBL
PRINTS BAND41 UniProtKB/TrEMBL
  ERMFAMILY UniProtKB/TrEMBL
PROSITE FERM_1 UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_3 UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
  SM01195 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  Second domain of FERM UniProtKB/TrEMBL
  Ubiquitin-like UniProtKB/TrEMBL
UniProt G5AP97 ENTREZGENE, UniProtKB/TrEMBL