Pde1c (phosphodiesterase 1C) - Rat Genome Database

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Gene: Pde1c (phosphodiesterase 1C) Heterocephalus glaber
Analyze
Symbol: Pde1c
Name: phosphodiesterase 1C
RGD ID: 18931931
Description: ENCODES a protein that exhibits calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity (ortholog); cAMP binding (ortholog); INVOLVED IN negative regulation of insulin secretion involved in cellular response to glucose stimulus (ortholog); response to calcium ion (ortholog); sensory perception of smell (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness (ortholog); autosomal dominant nonsyndromic deafness 74 (ortholog); genetic disease (ortholog); FOUND IN cilium (ortholog); lysosome (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247831,027,548 - 1,139,231 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247831,025,606 - 1,708,803 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Pde1c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247831,027,548 - 1,139,231 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247831,025,606 - 1,708,803 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PDE1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38731,616,777 - 32,428,224 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl731,751,179 - 32,428,131 (-)EnsemblGRCh38hg38GRCh38
GRCh37731,790,793 - 32,467,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36731,795,772 - 32,077,516 (-)NCBINCBI36Build 36hg18NCBI36
Build 34731,602,486 - 31,884,231NCBI
Celera731,779,557 - 32,325,238 (-)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef731,673,350 - 32,219,567 (-)NCBIHuRef
CHM1_1731,792,207 - 32,337,961 (-)NCBICHM1_1
T2T-CHM13v2.0731,754,475 - 32,567,499 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2731,840,922 - 32,386,609 (-)NCBI
Pde1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39656,046,783 - 56,629,590 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl656,046,789 - 56,629,472 (-)EnsemblGRCm39 Ensembl
GRCm38656,069,798 - 56,652,510 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl656,069,804 - 56,652,487 (-)EnsemblGRCm38mm10GRCm38
MGSCv37656,019,798 - 56,319,628 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36656,011,359 - 56,292,097 (-)NCBIMGSCv36mm8
Celera660,236,120 - 60,238,326 (-)NCBICelera
Celera656,847,453 - 57,126,888 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.65NCBI
Pde1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8486,629,074 - 87,108,147 (-)NCBIGRCr8
mRatBN7.2485,300,858 - 85,777,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl485,300,858 - 85,863,219 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx490,536,092 - 91,012,558 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0486,311,496 - 86,787,976 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0484,708,405 - 85,182,236 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0486,359,762 - 86,925,044 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl486,359,820 - 86,630,543 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04151,012,195 - 151,485,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4484,936,642 - 85,448,339 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1485,180,112 - 85,587,782 (-)NCBI
Celera480,156,679 - 80,622,825 (-)NCBICelera
Cytogenetic Map4q24NCBI
Pde1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541032,792,649 - 33,257,291 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541032,790,720 - 33,257,760 (-)NCBIChiLan1.0ChiLan1.0
PDE1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2636,436,114 - 37,235,708 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1784,760,632 - 85,560,321 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0732,225,293 - 33,037,627 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1732,477,361 - 33,030,078 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl732,343,701 - 33,029,405 (-)Ensemblpanpan1.1panPan2
PDE1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11444,250,612 - 44,543,818 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1444,145,534 - 44,644,937 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1443,683,659 - 44,165,857 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01444,194,159 - 44,675,717 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1444,193,155 - 44,675,842 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11444,315,468 - 44,607,684 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01443,982,193 - 44,460,807 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01444,346,723 - 44,834,997 (-)NCBIUU_Cfam_GSD_1.0
Pde1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511888,688,701 - 89,286,505 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364787,900,432 - 8,393,631 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364787,900,432 - 8,499,300 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDE1C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1840,820,644 - 41,409,087 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11840,818,316 - 41,410,555 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PDE1C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12126,094,604 - 26,712,127 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2126,501,264 - 26,598,053 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604278,073,957 - 78,643,089 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004856302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004856303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013076529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021237584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021237585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021237586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01059671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01059708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01004099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000021416   ⟹   ENSHGLP00000021212
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247831,027,548 - 1,139,231 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000021417   ⟹   ENSHGLP00000021213
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247831,027,548 - 1,138,812 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000021418   ⟹   ENSHGLP00000021214
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247831,068,332 - 1,139,231 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000021419   ⟹   ENSHGLP00000021215
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247831,068,332 - 1,138,537 (-)Ensembl
RefSeq Acc Id: XM_004856302   ⟹   XP_004856359
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247831,027,548 - 1,591,593 (-)NCBI
RefSeq Acc Id: XM_004856303   ⟹   XP_004856360
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247831,027,548 - 1,353,856 (-)NCBI
RefSeq Acc Id: XM_013076529   ⟹   XP_012931983
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247831,025,606 - 1,708,803 (-)NCBI
RefSeq Acc Id: XM_021237584   ⟹   XP_021093243
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247831,037,806 - 1,708,803 (-)NCBI
RefSeq Acc Id: XM_021237585   ⟹   XP_021093244
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247831,027,533 - 1,708,803 (-)NCBI
RefSeq Acc Id: XM_021237586   ⟹   XP_021093245
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247831,057,081 - 1,708,803 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_012931983   ⟸   XM_013076529
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021093244   ⟸   XM_021237585
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004856359   ⟸   XM_004856302
- Peptide Label: isoform X3
- UniProtKB: G5B2R9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004856360   ⟸   XM_004856303
- Peptide Label: isoform X5
- UniProtKB: A0A0N8ETK8 (UniProtKB/TrEMBL),   G5B2R9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093243   ⟸   XM_021237584
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021093245   ⟸   XM_021237586
- Peptide Label: isoform X4
RefSeq Acc Id: ENSHGLP00000021212   ⟸   ENSHGLT00000021416
RefSeq Acc Id: ENSHGLP00000021215   ⟸   ENSHGLT00000021419
RefSeq Acc Id: ENSHGLP00000021213   ⟸   ENSHGLT00000021417
RefSeq Acc Id: ENSHGLP00000021214   ⟸   ENSHGLT00000021418


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015158 Ensembl, ENTREZGENE
  ENSHGLG00100018980 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000021416 ENTREZGENE
  ENSHGLT00100026146 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1300.10 UniProtKB/TrEMBL
InterPro HD/PDEase_dom UniProtKB/TrEMBL
  PDEase UniProtKB/TrEMBL
  PDEase_catalytic_dom UniProtKB/TrEMBL
  PDEase_catalytic_dom_sf UniProtKB/TrEMBL
  PDEase_CS UniProtKB/TrEMBL
  PDEase_N UniProtKB/TrEMBL
NCBI Gene Pde1c ENTREZGENE
PANTHER CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C UniProtKB/TrEMBL
  CYCLIC NUCLEOTIDE PHOSPHODIESTERASE UniProtKB/TrEMBL
Pfam PDEase_I UniProtKB/TrEMBL
  PDEase_I_N UniProtKB/TrEMBL
PRINTS PDIESTERASE1 UniProtKB/TrEMBL
PROSITE PDEASE_I_1 UniProtKB/TrEMBL
  PDEASE_I_2 UniProtKB/TrEMBL
SMART HDc UniProtKB/TrEMBL
Superfamily-SCOP HD-domain/PDEase-like UniProtKB/TrEMBL
UniProt A0A0N8ETK8 ENTREZGENE, UniProtKB/TrEMBL
  G5B2R9 ENTREZGENE, UniProtKB/TrEMBL