Fkrp (fukutin related protein) - Rat Genome Database

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Gene: Fkrp (fukutin related protein) Heterocephalus glaber
Analyze
Symbol: Fkrp
Name: fukutin related protein
RGD ID: 18931335
Description: ENCODES a protein that exhibits dystroglycan binding (ortholog); identical protein binding (ortholog); laminin binding (ortholog); INVOLVED IN adult walking behavior (ortholog); basement membrane organization (ortholog); bone mineralization (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2I (ortholog); cardiomyopathy (ortholog); FOUND IN cytosol (ortholog); extracellular space (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fukutin-related protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,849,005 - 6,857,898 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,849,001 - 6,858,931 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult walking behavior  (ISO)
basement membrane organization  (ISO)
bone mineralization  (ISO)
brain development  (ISO)
camera-type eye development  (ISO)
central nervous system development  (ISO)
connective tissue development  (ISO)
connective tissue replacement  (ISO)
creatine metabolic process  (ISO)
diaphragm development  (ISO)
extracellular matrix organization  (ISO)
eye development  (ISO)
filtration diaphragm assembly  (ISO)
gene expression  (ISO)
glial cell differentiation  (ISO)
glycolytic process  (ISO)
glycoprotein biosynthetic process  (ISO)
heart development  (ISO)
heart morphogenesis  (ISO)
in utero embryonic development  (ISO)
inflammatory response  (ISO)
lipid metabolic process  (ISO)
localization of cell  (ISO)
maintenance of protein localization in endoplasmic reticulum  (ISO)
muscle cell differentiation  (ISO)
muscle contraction  (ISO)
muscle structure development  (ISO)
neuromuscular process  (ISO)
neuron migration  (ISO)
oxygen metabolic process  (ISO)
pentitol metabolic process  (ISO)
pentose metabolic process  (ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
protein glycosylation  (ISO)
protein import  (ISO)
protein localization  (ISO)
protein modification process  (ISO)
protein O-linked mannosylation  (ISO)
protein processing  (ISO)
protein tetramerization  (ISO)
reelin-mediated signaling pathway  (ISO)
respiratory system process  (ISO)
response to activity  (ISO)
response to alcohol  (ISO)
response to glucocorticoid  (ISO)
response to xenobiotic stimulus  (ISO)
skeletal muscle fiber differentiation  (ISO)
skeletal muscle organ development  (ISO)
skeletal muscle tissue development  (ISO)
skeletal muscle tissue regeneration  (ISO)
striated muscle cell differentiation  (ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Fkrp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,849,005 - 6,857,898 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,849,001 - 6,858,931 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FKRP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,744,760 - 46,758,575 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,746,046 - 46,776,988 (+)EnsemblGRCh38hg38GRCh38
GRCh371947,249,314 - 47,261,832 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,941,143 - 51,953,582 (+)NCBINCBI36Build 36hg18NCBI36
Build 341951,941,154 - 51,953,581NCBI
Celera1944,052,833 - 44,066,103 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,674,242 - 43,686,703 (+)NCBIHuRef
CHM1_11947,251,200 - 47,263,719 (+)NCBICHM1_1
T2T-CHM13v2.01949,570,337 - 49,584,398 (+)NCBIT2T-CHM13v2.0
Fkrp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,543,192 - 16,550,657 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,543,171 - 16,550,657 (-)EnsemblGRCm39 Ensembl
GRCm38716,809,267 - 16,816,732 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,809,246 - 16,816,732 (-)EnsemblGRCm38mm10GRCm38
MGSCv37717,394,616 - 17,402,081 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,967,789 - 15,975,237 (-)NCBIMGSCv36mm8
Celera714,007,271 - 14,014,735 (-)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
Fkrp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,607,769 - 86,615,045 (-)NCBIGRCr8
mRatBN7.2177,479,641 - 77,486,954 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,476,084 - 77,486,992 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,859,819 - 82,865,434 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,423,863 - 91,429,478 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,614,910 - 84,620,525 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,733,461 - 78,740,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,733,508 - 78,739,107 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,980,656 - 79,987,961 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,133,884 - 77,139,485 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,211,994 - 77,217,596 (-)NCBI
Celera171,964,734 - 71,970,335 (-)NCBICelera
Cytogenetic Map1q21NCBI
Fkrp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574786,758 - 788,348 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955574779,672 - 789,621 (+)NCBIChiLan1.0ChiLan1.0
FKRP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,895,811 - 52,905,652 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,766,677 - 54,776,808 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,738,339 - 43,748,250 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,268,889 - 52,277,888 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,273,546 - 52,276,341 (+)Ensemblpanpan1.1panPan2
FKRP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,166,527 - 109,177,393 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,168,644 - 109,178,319 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,646,333 - 108,657,154 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,692,868 - 109,703,829 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,693,019 - 109,702,692 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,370,001 - 109,380,952 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,004,334 - 109,015,149 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,872,874 - 109,883,835 (-)NCBIUU_Cfam_GSD_1.0
Fkrp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934918,958,974 - 18,968,719 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936664578,126 - 586,795 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936664577,109 - 586,848 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKRP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,627,471 - 52,639,253 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,627,466 - 52,639,255 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,948,142 - 47,957,965 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FKRP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,100,399 - 40,128,340 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,126,321 - 40,127,808 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,812,461 - 19,825,085 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000025179   ⟹   ENSHGLP00000024957
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248326,849,005 - 6,857,898 (-)Ensembl
RefSeq Acc Id: XM_004867089   ⟹   XP_004867146
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,849,001 - 6,857,941 (-)NCBI
RefSeq Acc Id: XM_013066322   ⟹   XP_012921776
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,849,001 - 6,858,470 (-)NCBI
RefSeq Acc Id: XM_021246167   ⟹   XP_021101826
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,849,001 - 6,858,931 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004867146 (Get FASTA)   NCBI Sequence Viewer  
  XP_012921776 (Get FASTA)   NCBI Sequence Viewer  
  XP_021101826 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024957
RefSeq Acc Id: XP_021101826   ⟸   XM_021246167
RefSeq Acc Id: XP_012921776   ⟸   XM_013066322
RefSeq Acc Id: XP_004867146   ⟸   XM_004867089
Ensembl Acc Id: ENSHGLP00000024957   ⟸   ENSHGLT00000025179


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017783 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000025179 ENTREZGENE
NCBI Gene Fkrp ENTREZGENE
UniProt A0AAX6Q496_HETGA UniProtKB/TrEMBL