Tut1 (terminal uridylyl transferase 1, U6 snRNA-specific) - Rat Genome Database

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Gene: Tut1 (terminal uridylyl transferase 1, U6 snRNA-specific) Heterocephalus glaber
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Symbol: Tut1
Name: terminal uridylyl transferase 1, U6 snRNA-specific
RGD ID: 18929903
Description: ENCODES a protein that exhibits enzyme binding (ortholog); enzyme-substrate adaptor activity (ortholog); mRNA 3'-UTR binding (ortholog); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); histone mRNA catabolic process (ortholog); mRNA 3'-end processing (ortholog); ASSOCIATED WITH intellectual disability (ortholog); leukocyte adhesion deficiency 3 (ortholog); FOUND IN cytosol (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: speckle targeted PIP5K1A-regulated poly(A) polymerase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,112,309 - 1,123,959 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,113,331 - 1,123,930 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tut1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,112,309 - 1,123,959 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,113,331 - 1,123,930 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TUT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,575,052 - 62,591,523 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,575,045 - 62,591,637 (-)EnsemblGRCh38hg38GRCh38
GRCh371162,342,524 - 62,358,995 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,099,096 - 62,115,592 (-)NCBINCBI36Build 36hg18NCBI36
Build 341162,099,096 - 62,115,592NCBI
Celera1159,671,911 - 59,688,674 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,671,464 - 58,688,025 (-)NCBIHuRef
CHM1_11162,225,562 - 62,242,155 (-)NCBICHM1_1
T2T-CHM13v2.01162,564,505 - 62,580,971 (-)NCBIT2T-CHM13v2.0
Tut1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,931,199 - 8,943,572 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,931,211 - 8,943,574 (+)EnsemblGRCm39 Ensembl
GRCm38198,953,832 - 8,966,210 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,953,847 - 8,966,210 (+)EnsemblGRCm38mm10GRCm38
MGSCv37199,028,340 - 9,040,700 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36199,020,892 - 9,033,255 (+)NCBIMGSCv36mm8
Celera198,714,449 - 8,726,831 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.04NCBI
Tut1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,277,802 - 215,288,869 (+)NCBIGRCr8
mRatBN7.21205,848,691 - 205,859,767 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,848,772 - 205,859,764 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,257,244 - 214,268,332 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,292,151 - 221,303,134 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,985,008 - 213,995,991 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,151,462 - 225,162,445 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,151,404 - 225,162,595 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,088,997 - 232,100,065 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,629,025 - 211,640,008 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1203,361,578 - 203,372,574 (+)NCBICelera
Cytogenetic Map1q43NCBI
Tut1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599596,650 - 606,486 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955599596,565 - 606,498 (+)NCBIChiLan1.0ChiLan1.0
TUT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,801,920 - 63,819,095 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11164,844,628 - 64,861,803 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01157,932,582 - 57,949,473 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,287,375 - 61,303,784 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,287,375 - 61,303,784 (-)Ensemblpanpan1.1panPan2
TUT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,048,519 - 54,061,431 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,048,563 - 54,061,415 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,653,541 - 52,666,455 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01855,100,852 - 55,112,992 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,100,856 - 55,126,764 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,197,090 - 54,210,000 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,771,809 - 53,783,676 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,567,401 - 54,580,143 (+)NCBIUU_Cfam_GSD_1.0
Eef1g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,566,720 - 10,577,626 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581665,782 - 679,190 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581665,751 - 691,448 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TUT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,148,560 - 9,161,905 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,148,563 - 9,161,918 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,494,206 - 8,506,620 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TUT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,313,208 - 11,325,912 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,312,843 - 11,326,777 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,648,848 - 108,664,259 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000003779   ⟹   ENSHGLP00000003724
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249261,112,309 - 1,123,959 (-)Ensembl
RefSeq Acc Id: XM_004874365   ⟹   XP_004874422
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249261,113,331 - 1,123,930 (-)NCBI
RefSeq Acc Id: XM_004874367   ⟹   XP_004874424
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249261,113,331 - 1,121,757 (-)NCBI
RefSeq Acc Id: XM_004874368   ⟹   XP_004874425
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249261,113,331 - 1,123,929 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004874422 (Get FASTA)   NCBI Sequence Viewer  
  XP_004874424 (Get FASTA)   NCBI Sequence Viewer  
  XP_004874425 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003724
RefSeq Acc Id: XP_004874422   ⟸   XM_004874365
- Peptide Label: isoform X2
- UniProtKB: G5AYH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004874425   ⟸   XM_004874368
- Peptide Label: isoform X1
- UniProtKB: G5AYH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004874424   ⟸   XM_004874367
- Peptide Label: isoform X3
- UniProtKB: G5AYH3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000003724   ⟸   ENSHGLT00000003779


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002742 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000003779 ENTREZGENE
Gene3D-CATH 1.10.1410.10 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro MTPAP-like_central UniProtKB/TrEMBL
  NT_sf UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  PAP_assoc UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  Star-PAP_RRM UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Tut1 ENTREZGENE
PANTHER POLY A POLYMERASE CID PAP -RELATED UniProtKB/TrEMBL
  SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE UniProtKB/TrEMBL
Pfam MTPAP-like_central UniProtKB/TrEMBL
  PAP_assoc UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
  zf-met UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP beta-beta-alpha zinc fingers UniProtKB/TrEMBL
  Nucleotidyltransferase UniProtKB/TrEMBL
  PAP/OAS1 substrate-binding domain UniProtKB/TrEMBL
  RNA-binding domain, RBD UniProtKB/TrEMBL
UniProt A0AAX6QF40_HETGA UniProtKB/TrEMBL
  A0AAX6QIE3_HETGA UniProtKB/TrEMBL
  A0AAX6QIJ6_HETGA UniProtKB/TrEMBL
  G5AYH3 ENTREZGENE, UniProtKB/TrEMBL