Rab18 (RAB18, member RAS oncogene family) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Rab18 (RAB18, member RAS oncogene family) Heterocephalus glaber
Analyze
Symbol: Rab18
Name: RAB18, member RAS oncogene family
RGD ID: 18928960
Description: ENCODES a protein that exhibits GDP binding (ortholog); INVOLVED IN endoplasmic reticulum tubular network organization (ortholog); import into nucleus (ortholog); lipid droplet organization (ortholog); ASSOCIATED WITH genetic disease (ortholog); Warburg micro syndrome (ortholog); Warburg micro syndrome 3 (ortholog); FOUND IN endoplasmic reticulum tubular network (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ras-related protein Rab-18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248055,918,956 - 5,956,206 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Rab18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248055,918,956 - 5,956,206 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RAB18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381027,504,304 - 27,542,239 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1027,504,174 - 27,543,207 (+)EnsemblGRCh38hg38GRCh38
GRCh371027,793,233 - 27,831,168 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361027,833,255 - 27,869,105 (+)NCBINCBI36Build 36hg18NCBI36
Build 341027,833,254 - 27,869,103NCBI
Celera1027,556,861 - 27,592,716 (+)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1027,509,631 - 27,547,699 (+)NCBIHuRef
CHM1_11027,792,934 - 27,831,114 (+)NCBICHM1_1
T2T-CHM13v2.01027,534,698 - 27,572,633 (+)NCBIT2T-CHM13v2.0
Rab18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,765,167 - 6,791,606 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,733,905 - 6,794,429 (+)EnsemblGRCm39 Ensembl
GRCm38186,765,167 - 6,791,606 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,733,905 - 6,794,429 (+)EnsemblGRCm38mm10GRCm38
MGSCv37186,765,203 - 6,790,229 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36186,765,203 - 6,790,229 (+)NCBIMGSCv36mm8
Celera186,810,932 - 6,835,956 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.53NCBI
Rab18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81759,639,264 - 59,670,653 (+)NCBIGRCr8
mRatBN7.21754,944,099 - 54,976,093 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1754,943,955 - 54,976,043 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1758,113,041 - 58,144,409 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01762,116,142 - 62,147,501 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01756,282,675 - 56,314,053 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01759,844,781 - 59,876,170 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1759,844,781 - 59,876,164 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01761,632,659 - 61,664,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,497,924 - 63,529,233 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11763,508,756 - 63,540,065 (+)NCBI
Celera1756,284,171 - 56,315,512 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
Rab18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554621,380,156 - 1,411,804 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554621,380,158 - 1,411,804 (+)NCBIChiLan1.0ChiLan1.0
RAB18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2840,160,001 - 40,195,980 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11040,165,327 - 40,202,269 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01027,639,726 - 27,676,555 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11028,001,249 - 28,037,527 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1028,001,249 - 28,037,527 (+)Ensemblpanpan1.1panPan2
RAB18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.126,071,944 - 6,112,064 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl26,073,534 - 6,111,928 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha25,193,565 - 5,233,656 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0216,951,517 - 16,991,685 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl216,750,761 - 16,991,653 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.0216,184,372 - 16,224,447 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0216,588,956 - 16,629,062 (-)NCBIUU_Cfam_GSD_1.0
Rab18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093447,324,844 - 7,358,505 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366131,875,366 - 1,909,080 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1038,970,586 - 39,004,971 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11038,970,381 - 39,004,975 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21053,835,490 - 53,867,558 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1927,048,653 - 27,085,034 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl927,048,647 - 27,082,924 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605133,068,806 - 33,105,257 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004861832   ⟹   XP_004861889
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248055,918,986 - 5,956,206 (+)NCBI
RefSeq Acc Id: XM_004861833   ⟹   XP_004861890
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248055,918,956 - 5,956,206 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004861889 (Get FASTA)   NCBI Sequence Viewer  
  XP_004861890 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15258 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005973
Reference Protein Sequences
RefSeq Acc Id: XP_004861890   ⟸   XM_004861833
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004861889   ⟸   XM_004861832
- Peptide Label: isoform X1
- UniProtKB: G5C147 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004365 ENTREZGENE
Ensembl Transcript ENSHGLT00000006047 ENTREZGENE
Gene3D-CATH P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Sigma_54_int_dom_ATP-bd_1 UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
NCBI Gene Rab18 ENTREZGENE
PANTHER RAS-RELATED PROTEIN RAB UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-32D UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  SIGMA54_INTERACT_1 UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
UniProt G5C147 ENTREZGENE, UniProtKB/TrEMBL