Dlx1 (distal-less homeobox 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Dlx1 (distal-less homeobox 1) Heterocephalus glaber
Analyze
Symbol: Dlx1
Name: distal-less homeobox 1
RGD ID: 18928902
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN cytosol (inferred); intracellular membrane-bounded organelle (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Homeobox protein DLX-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247879,514,573 - 9,519,724 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247879,514,170 - 9,519,309 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dlx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247879,514,573 - 9,519,724 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247879,514,170 - 9,519,309 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DLX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382172,085,507 - 172,089,674 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2172,084,740 - 172,089,677 (+)EnsemblGRCh38hg38GRCh38
GRCh372172,950,235 - 172,954,402 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362172,658,454 - 172,662,648 (+)NCBINCBI36Build 36hg18NCBI36
Celera2166,566,309 - 166,570,503 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2164,830,459 - 164,834,653 (+)NCBIHuRef
CHM1_12172,957,684 - 172,961,878 (+)NCBICHM1_1
T2T-CHM13v2.02172,570,383 - 172,575,917 (+)NCBIT2T-CHM13v2.0
Dlx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39271,358,457 - 71,364,325 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl271,358,457 - 71,364,325 (+)EnsemblGRCm39 Ensembl
GRCm38271,528,113 - 71,533,981 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl271,528,113 - 71,533,981 (+)EnsemblGRCm38mm10GRCm38
MGSCv37271,367,502 - 71,372,037 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36271,330,284 - 71,334,819 (+)NCBIMGSCv36mm8
Celera273,193,503 - 73,198,048 (+)NCBICelera
Cytogenetic Map2C2NCBI
cM Map242.61NCBI
Dlx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8376,763,864 - 76,768,454 (+)NCBIGRCr8
mRatBN7.2356,356,190 - 56,360,780 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl356,356,190 - 56,360,780 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx359,754,121 - 59,758,700 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0368,337,729 - 68,342,308 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0366,099,889 - 66,104,437 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0358,164,931 - 58,169,521 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl358,164,931 - 58,169,521 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0364,650,292 - 64,654,882 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4353,837,052 - 53,841,642 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1353,733,423 - 53,738,014 (+)NCBI
Celera355,903,832 - 55,908,422 (+)NCBICelera
Cytogenetic Map3q23NCBI
Dlx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554492,920,478 - 2,924,667 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554492,920,705 - 2,924,667 (-)NCBIChiLan1.0ChiLan1.0
DLX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21374,768,913 - 74,773,852 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B74,784,291 - 74,788,828 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B59,382,156 - 59,387,100 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B176,839,361 - 176,843,909 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B176,839,721 - 176,843,909 (+)Ensemblpanpan1.1panPan2
DLX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13616,485,158 - 16,489,397 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3616,484,859 - 16,487,886 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3616,493,520 - 16,498,111 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03616,605,670 - 16,610,243 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3616,605,155 - 16,610,240 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13616,693,224 - 16,697,802 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03616,693,589 - 16,698,176 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03616,797,500 - 16,802,082 (+)NCBIUU_Cfam_GSD_1.0
Dlx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303133,693,510 - 133,698,405 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365092,248,181 - 2,250,991 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365092,248,181 - 2,250,991 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1578,185,790 - 78,191,226 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11578,186,667 - 78,191,788 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21587,613,190 - 87,617,605 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DLX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11057,586,452 - 57,599,071 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1057,590,838 - 57,595,266 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040141,953,127 - 141,958,074 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000012549   ⟹   ENSHGLP00000012414
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247879,514,573 - 9,519,724 (+)Ensembl
RefSeq Acc Id: XM_004857675   ⟹   XP_004857732
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247879,514,170 - 9,519,309 (+)NCBI
RefSeq Acc Id: XM_021238622   ⟹   XP_021094281
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247879,514,170 - 9,519,309 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004857732 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094281 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA98571 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012414
RefSeq Acc Id: XP_004857732   ⟸   XM_004857675
- UniProtKB: G5ANG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094281   ⟸   XM_021238622
- UniProtKB: G5ANG1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000012414   ⟸   ENSHGLT00000012549


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008870 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000012549 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Distal-less_Homeobox_TF UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/TrEMBL
  HTH_motif UniProtKB/TrEMBL
KEGG Report hgl:101703884 UniProtKB/TrEMBL
NCBI Gene Dlx1 ENTREZGENE
PANTHER HOMEOBOX PROTEIN UniProtKB/TrEMBL
  HOMEOBOX PROTEIN DLX-1 UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PRINTS HOMEOBOX UniProtKB/TrEMBL
  HTHREPRESSR UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt G5ANG1 ENTREZGENE, UniProtKB/TrEMBL