Dst (dystonin) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Dst (dystonin) Heterocephalus glaber
Analyze
Symbol: Dst
Name: dystonin
RGD ID: 18928837
Description: ENCODES a protein that exhibits integrin binding (ortholog); microtubule plus-end binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN axonogenesis (ortholog); cell motility (ortholog); cytoskeleton organization (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); cardiomyopathy (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN actin cytoskeleton (ortholog); axon (ortholog); cell leading edge (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bullous pemphigoid antigen 1 isoform 1eA; Bullous pemphigoid antigen 1, isoforms 6/9/10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475318,321,591 - 18,674,329 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475318,321,591 - 18,778,090 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dst
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475318,321,591 - 18,674,329 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475318,321,591 - 18,778,090 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38656,457,996 - 56,954,830 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl656,457,987 - 56,954,830 (-)EnsemblGRCh38hg38GRCh38
GRCh37656,322,794 - 56,819,628 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36656,430,744 - 56,816,422 (-)NCBINCBI36Build 36hg18NCBI36
Celera657,984,956 - 58,169,868 (-)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef656,158,712 - 56,652,953 (-)NCBIHuRef
CHM1_1656,325,822 - 56,819,767 (-)NCBICHM1_1
T2T-CHM13v2.0656,299,279 - 56,793,877 (-)NCBIT2T-CHM13v2.0
Dst
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,946,969 - 34,347,743 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,947,306 - 34,347,742 (+)EnsemblGRCm39 Ensembl
GRCm38133,907,888 - 34,308,662 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,908,225 - 34,308,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv37134,068,670 - 34,365,497 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,956,371 - 34,253,198 (+)NCBIMGSCv36mm8
Celera133,786,289 - 34,078,455 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map112.91NCBI
Dst
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8943,631,716 - 44,025,535 (+)NCBIGRCr8
mRatBN7.2936,135,657 - 36,529,617 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl936,135,284 - 36,529,615 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx944,733,010 - 45,026,540 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0949,864,187 - 50,157,722 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0948,146,091 - 48,439,616 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0937,902,336 - 38,296,961 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl937,902,303 - 38,196,273 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0937,586,701 - 37,979,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4932,757,554 - 33,051,275 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1932,758,967 - 33,051,638 (+)NCBI
Celera933,927,773 - 34,321,367 (+)NCBICelera
Cytogenetic Map9q21NCBI
Dst
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555023,267,527 - 3,610,823 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555023,175,918 - 3,610,823 (+)NCBIChiLan1.0ChiLan1.0
DST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2570,931,526 - 71,425,728 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1666,808,384 - 67,306,877 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0656,014,832 - 56,513,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1657,646,402 - 58,144,563 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl657,646,402 - 58,039,636 (-)Ensemblpanpan1.1panPan2
DST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11223,715,637 - 24,195,220 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1223,716,466 - 24,195,416 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1223,605,476 - 24,084,492 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01224,213,304 - 24,693,512 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1224,213,299 - 24,576,848 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11223,705,703 - 24,191,186 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01223,812,683 - 24,292,223 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01223,943,092 - 24,423,680 (-)NCBIUU_Cfam_GSD_1.0
Dst
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494659,187,310 - 59,615,541 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364764,344,716 - 4,771,878 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364764,344,673 - 4,772,892 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl728,812,252 - 29,300,152 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1728,812,423 - 29,300,149 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2733,273,626 - 33,751,908 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11714,652,044 - 15,133,172 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1714,652,233 - 15,133,862 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605821,021,492 - 21,263,389 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021259192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01034102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01034114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01005370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH170682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000021222   ⟹   ENSHGLP00000021019
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475318,321,591 - 18,373,455 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000021223   ⟹   ENSHGLP00000021020
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475318,322,613 - 18,674,329 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000021224   ⟹   ENSHGLP00000021021
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475318,322,613 - 18,491,236 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000021225   ⟹   ENSHGLP00000021022
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475318,464,984 - 18,491,236 (-)Ensembl
RefSeq Acc Id: XM_021259192   ⟹   XP_021114851
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475318,321,591 - 18,778,090 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021114851 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09643 (Get FASTA)   NCBI Sequence Viewer  
  JAN98262 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021114851   ⟸   XM_021259192
RefSeq Acc Id: ENSHGLP00000021019   ⟸   ENSHGLT00000021222
RefSeq Acc Id: ENSHGLP00000021022   ⟸   ENSHGLT00000021225
RefSeq Acc Id: ENSHGLP00000021020   ⟸   ENSHGLT00000021223
RefSeq Acc Id: ENSHGLP00000021021   ⟸   ENSHGLT00000021224


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015021 Ensembl
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  1.20.5.170 UniProtKB/TrEMBL
  1.20.58.1060 UniProtKB/TrEMBL
  1.20.58.60 UniProtKB/TrEMBL
  3.30.160.780 UniProtKB/TrEMBL
  3.90.1290.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro Actinin_actin-bd_CS UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Desmoplakin_SH3 UniProtKB/TrEMBL
  Desmoplakin_Spectrin-like UniProtKB/TrEMBL
  PCN-like_spectrin-like_rpt UniProtKB/TrEMBL
  Plakin UniProtKB/TrEMBL
  Plakin_repeat_sf UniProtKB/TrEMBL
  Plectin_repeat UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/TrEMBL
NCBI Gene Dst ENTREZGENE
PANTHER DESMOPLAKIN UniProtKB/TrEMBL
  PTHR23169 UniProtKB/TrEMBL
Pfam PF00307 UniProtKB/TrEMBL
  Plectin UniProtKB/TrEMBL
  SH3_10 UniProtKB/TrEMBL
  Spectrin UniProtKB/TrEMBL
  Spectrin_3 UniProtKB/TrEMBL
  Spectrin_4 UniProtKB/TrEMBL
  Spectrin_like UniProtKB/TrEMBL
  SR_plectin_7 UniProtKB/TrEMBL
PROSITE ACTININ_1 UniProtKB/TrEMBL
  ACTININ_2 UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART PLEC UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
  SPEC UniProtKB/TrEMBL
Superfamily-SCOP Spectrin repeat UniProtKB/TrEMBL
  SSF47576 UniProtKB/TrEMBL
  SSF75399 UniProtKB/TrEMBL
UniProt A0A0P6J6L9_HETGA UniProtKB/TrEMBL