Marchf6 (membrane associated ring-CH-type finger 6) - Rat Genome Database

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Gene: Marchf6 (membrane associated ring-CH-type finger 6) Heterocephalus glaber
Analyze
Symbol: Marchf6 (Ensembl: MARCH6)
Name: membrane associated ring-CH-type finger 6
RGD ID: 18927765
Description: ENCODES a protein that exhibits enzyme binding (ortholog); ubiquitin conjugating enzyme binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein K48-linked ubiquitination (ortholog); ASSOCIATED WITH familial adult myoclonic epilepsy 3 (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase MARCH6; March6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247517,715,007 - 7,780,460 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247517,715,065 - 7,781,320 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Marchf6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247517,715,007 - 7,780,460 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247517,715,065 - 7,781,320 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MARCHF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38510,353,695 - 10,440,388 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl510,353,695 - 10,440,388 (+)EnsemblGRCh38hg38GRCh38
GRCh37510,353,807 - 10,440,500 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36510,406,828 - 10,488,491 (+)NCBINCBI36Build 36hg18NCBI36
Build 34510,406,827 - 10,488,491NCBI
Celera510,391,947 - 10,473,622 (+)NCBICelera
Cytogenetic Map5p15.2NCBI
HuRef510,338,021 - 10,424,590 (+)NCBIHuRef
CHM1_1510,353,128 - 10,440,366 (+)NCBICHM1_1
T2T-CHM13v2.0510,292,877 - 10,379,523 (+)NCBIT2T-CHM13v2.0
Marchf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391531,456,045 - 31,531,172 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1531,456,037 - 31,531,199 (-)EnsemblGRCm39 Ensembl
GRCm381531,455,899 - 31,531,082 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1531,455,891 - 31,531,053 (-)EnsemblGRCm38mm10GRCm38
MGSCv371531,385,654 - 31,460,792 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361531,400,488 - 31,475,626 (-)NCBIMGSCv36mm8
Celera1532,146,454 - 32,221,649 (-)NCBICelera
Cytogenetic Map15B2NCBI
cM Map1512.95NCBI
Marchf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8284,166,570 - 84,243,817 (-)NCBIGRCr8
mRatBN7.2282,455,686 - 82,532,917 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl282,455,689 - 82,532,910 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx289,495,758 - 89,575,122 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0287,617,336 - 87,696,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0282,673,618 - 82,752,982 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0284,533,546 - 84,608,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl284,536,669 - 84,608,712 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02104,206,630 - 104,281,918 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4283,544,604 - 83,622,254 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera277,979,979 - 78,056,887 (-)NCBICelera
Cytogenetic Map2q23NCBI
Marchf6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955426228,788 - 278,888 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955426228,807 - 278,888 (+)NCBIChiLan1.0ChiLan1.0
MARCHF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2410,594,867 - 10,681,923 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan158,748,938 - 8,834,711 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0510,666,978 - 10,753,050 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1510,524,958 - 10,608,046 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl510,524,958 - 10,608,046 (+)Ensemblpanpan1.1panPan2
MARCHF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1343,880,988 - 3,947,127 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl343,884,487 - 3,943,035 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha348,383,624 - 8,466,476 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0343,785,457 - 3,868,858 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl343,786,417 - 3,869,038 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1343,835,287 - 3,918,110 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0343,813,874 - 3,897,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0344,044,972 - 4,127,896 (-)NCBIUU_Cfam_GSD_1.0
Marchf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213236,892,183 - 236,966,037 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366432,455,328 - 2,507,225 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366432,455,496 - 2,507,185 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MARCHF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1672,044,093 - 72,127,863 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11672,043,294 - 72,127,869 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21678,141,955 - 78,228,049 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MARCHF6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.149,891,847 - 9,970,617 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl49,891,580 - 9,970,300 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606418,574,413 - 18,654,209 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000005295   ⟹   ENSHGLP00000005226
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247517,715,007 - 7,780,460 (+)Ensembl
RefSeq Acc Id: XM_004845184   ⟹   XP_004845241
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247517,715,065 - 7,781,320 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004845241 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB08924 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005226
GenBank Protein JAN99580 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004845241   ⟸   XM_004845184
- UniProtKB: A0A0P6K3Z0 (UniProtKB/TrEMBL),   G5BI13 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000005226   ⟸   ENSHGLT00000005295


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003823 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005295 ENTREZGENE
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Znf_RING-CH UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report hgl:101724762 UniProtKB/TrEMBL
NCBI Gene Marchf6 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 UniProtKB/TrEMBL
  SSM4 PROTEIN UniProtKB/TrEMBL
Pfam RINGv UniProtKB/TrEMBL
PROSITE ZF_RING_CH UniProtKB/TrEMBL
SMART RINGv UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A0P6K3Z0 ENTREZGENE, UniProtKB/TrEMBL
  G5BI13 ENTREZGENE, UniProtKB/TrEMBL