Rars2 (arginyl-tRNA synthetase 2, mitochondrial) - Rat Genome Database

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Gene: Rars2 (arginyl-tRNA synthetase 2, mitochondrial) Heterocephalus glaber
Analyze
Symbol: Rars2
Name: arginyl-tRNA synthetase 2, mitochondrial
RGD ID: 18927662
Description: ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); arginine-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN arginyl-tRNA aminoacylation (inferred); mitochondrial translation (inferred); translation (inferred); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; ASSOCIATED WITH cerebellar hypoplasia (ortholog); congenital disorder of glycosylation (ortholog); congenital disorder of glycosylation type IIf (ortholog); FOUND IN mitochondrial membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable arginine--tRNA ligase, mitochondrial; putative arginine--tRNA ligase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247996,728,610 - 6,803,716 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247996,728,967 - 6,804,846 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rars2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247996,728,610 - 6,803,716 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247996,728,967 - 6,804,846 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RARS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38687,513,938 - 87,589,987 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl687,513,459 - 87,590,028 (-)EnsemblGRCh38hg38GRCh38
GRCh37688,223,656 - 88,299,705 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36688,280,820 - 88,356,440 (-)NCBINCBI36Build 36hg18NCBI36
Build 34688,280,819 - 88,356,440NCBI
Celera688,642,914 - 88,718,095 (-)NCBICelera
Cytogenetic Map6q15NCBI
HuRef685,440,335 - 85,515,340 (-)NCBIHuRef
CHM1_1688,321,542 - 88,397,093 (-)NCBICHM1_1
T2T-CHM13v2.0688,722,691 - 88,798,283 (-)NCBIT2T-CHM13v2.0
Rars2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39434,614,941 - 34,660,167 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl434,614,957 - 34,660,167 (+)EnsemblGRCm39 Ensembl
GRCm38434,614,957 - 34,660,167 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl434,614,957 - 34,660,167 (+)EnsemblGRCm38mm10GRCm38
MGSCv37434,562,207 - 34,607,416 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36434,803,865 - 34,849,051 (+)NCBIMGSCv36mm8
Celera434,344,511 - 34,389,753 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map416.84NCBI
Rars2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8553,976,808 - 54,029,715 (+)NCBIGRCr8
mRatBN7.2549,181,517 - 49,238,664 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl549,181,565 - 49,233,276 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx551,374,882 - 51,416,069 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0552,975,113 - 53,016,292 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0552,880,718 - 52,927,929 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0550,075,510 - 50,127,625 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl550,075,527 - 50,127,424 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0554,644,464 - 54,696,575 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4551,226,723 - 51,268,906 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1551,222,529 - 51,269,081 (+)NCBI
Celera547,932,029 - 47,973,187 (+)NCBICelera
Cytogenetic Map5q21NCBI
Rars2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541114,470,479 - 14,527,895 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541114,470,479 - 14,527,895 (-)NCBIChiLan1.0ChiLan1.0
RARS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25107,595,648 - 107,671,472 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16105,489,500 - 105,565,261 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0685,391,061 - 85,466,888 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1688,665,540 - 88,741,377 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl688,665,543 - 88,741,371 (-)Ensemblpanpan1.1panPan2
RARS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11246,993,787 - 47,047,295 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1246,992,959 - 47,047,240 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1246,801,423 - 46,855,247 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01247,799,414 - 47,853,496 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1247,799,947 - 47,853,453 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11247,091,263 - 47,145,091 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01247,018,769 - 47,072,566 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01247,208,453 - 47,261,889 (-)NCBIUU_Cfam_GSD_1.0
Rars2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494682,127,597 - 82,189,048 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365104,281,626 - 4,343,276 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365104,281,847 - 4,343,271 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RARS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl155,893,480 - 55,982,068 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1155,906,508 - 55,982,094 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2162,646,000 - 62,675,186 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RARS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11311,995,422 - 12,068,150 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1311,995,453 - 12,068,138 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040188,249,165 - 188,322,332 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000002148   ⟹   ENSHGLP00000002100
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247996,728,610 - 6,803,716 (+)Ensembl
RefSeq Acc Id: XM_004860233   ⟹   XP_004860290
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247996,728,967 - 6,804,846 (+)NCBI
RefSeq Acc Id: XM_004860234   ⟹   XP_004860291
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247996,728,967 - 6,804,846 (+)NCBI
RefSeq Acc Id: XM_013077963   ⟹   XP_012933417
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247996,728,967 - 6,804,846 (+)NCBI
RefSeq Acc Id: XM_021240782   ⟹   XP_021096441
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247996,728,967 - 6,804,846 (+)NCBI
RefSeq Acc Id: XM_021240783   ⟹   XP_021096442
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247996,728,981 - 6,804,846 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004860290 (Get FASTA)   NCBI Sequence Viewer  
  XP_004860291 (Get FASTA)   NCBI Sequence Viewer  
  XP_012933417 (Get FASTA)   NCBI Sequence Viewer  
  XP_021096441 (Get FASTA)   NCBI Sequence Viewer  
  XP_021096442 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002100
GenBank Protein JAN99481 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004860290   ⟸   XM_004860233
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J7B5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860291   ⟸   XM_004860234
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021096441   ⟸   XM_021240782
- Peptide Label: isoform X2
- UniProtKB: G5B6Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012933417   ⟸   XM_013077963
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021096442   ⟸   XM_021240783
- Peptide Label: isoform X5
RefSeq Acc Id: ENSHGLP00000002100   ⟸   ENSHGLT00000002148


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001593 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000002148 ENTREZGENE
Gene3D-CATH 3.30.1360.70 UniProtKB/TrEMBL
  3.40.50.620 UniProtKB/TrEMBL
InterPro aa-tRNA-synth_I_CS UniProtKB/TrEMBL
  Arg-tRNA-ligase UniProtKB/TrEMBL
  Arg-tRNA-synth_N_sf UniProtKB/TrEMBL
  ArgRS_core UniProtKB/TrEMBL
  DALR_anticod-bd UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
  tRNAsynth_Ia_anticodon-bd UniProtKB/TrEMBL
KEGG Report hgl:101701322 UniProtKB/TrEMBL
NCBI Gene Rars2 ENTREZGENE
PANTHER ARGININE--TRNA LIGASE, CYTOPLASMIC-RELATED UniProtKB/TrEMBL
  PTHR11956 UniProtKB/TrEMBL
Pfam DALR_1 UniProtKB/TrEMBL
  tRNA-synt_1d UniProtKB/TrEMBL
PRINTS TRNASYNTHARG UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_I UniProtKB/TrEMBL
SMART DALR_1 UniProtKB/TrEMBL
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/TrEMBL
  SSF47323 UniProtKB/TrEMBL
  SSF55190 UniProtKB/TrEMBL
UniProt A0A0P6J7B5 ENTREZGENE, UniProtKB/TrEMBL
  G5B6Y5 ENTREZGENE, UniProtKB/TrEMBL