Dpp6 (dipeptidyl peptidase like 6) - Rat Genome Database

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Gene: Dpp6 (dipeptidyl peptidase like 6) Heterocephalus glaber
Analyze
Symbol: Dpp6
Name: dipeptidyl peptidase like 6
RGD ID: 18927639
Description: ENCODES a protein that exhibits dipeptidyl-peptidase activity (ortholog); INVOLVED IN establishment of localization in cell (ortholog); neuronal action potential (ortholog); positive regulation of potassium ion transmembrane transport (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN cell surface (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Dipeptidyl aminopeptidase-like protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248002,725,253 - 3,585,409 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248002,725,353 - 3,585,987 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dpp6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248002,725,253 - 3,585,409 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248002,725,353 - 3,585,987 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DPP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387153,748,133 - 154,894,285 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7153,748,133 - 154,894,285 (+)EnsemblGRCh38hg38GRCh38
GRCh377153,445,218 - 154,685,995 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367154,060,464 - 154,316,928 (+)NCBINCBI36Build 36hg18NCBI36
Build 367153,380,710 - 153,894,933 (+)NCBINCBI36Build 36hg18NCBI36
Build 347153,867,178 - 154,122,809NCBI
Celera7148,318,756 - 148,319,129 (-)NCBICelera
Celera7148,524,570 - 149,103,154 (+)NCBICelera
Cytogenetic Map7q36.2NCBI
HuRef7147,386,496 - 147,386,897 (+)NCBIHuRef
HuRef7148,164,313 - 148,419,023 (+)NCBIHuRef
HuRef7147,843,601 - 148,104,076 (+)NCBIHuRef
CHM1_17153,592,891 - 154,272,396 (+)NCBICHM1_1
CHM1_17154,437,907 - 154,692,518 (+)NCBICHM1_1
T2T-CHM13v2.07154,922,684 - 156,069,555 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27152,913,032 - 153,914,021 (+)NCBI
Dpp6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39527,022,355 - 27,932,498 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl527,022,201 - 27,932,503 (+)EnsemblGRCm39 Ensembl
GRCm38526,817,357 - 27,727,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl526,817,203 - 27,727,505 (+)EnsemblGRCm38mm10GRCm38
MGSCv37527,143,897 - 28,054,040 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36527,148,144 - 28,057,245 (+)NCBIMGSCv36mm8
Celera524,366,865 - 25,273,913 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map512.92NCBI
Dpp6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr848,323,220 - 9,242,694 (-)NCBIGRCr8
mRatBN7.247,589,386 - 8,508,666 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl47,591,009 - 8,508,532 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx412,601,019 - 13,257,605 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.048,415,266 - 9,071,862 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.046,761,456 - 7,425,308 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.044,021,021 - 4,943,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl44,021,008 - 4,473,307 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.044,060,496 - 4,970,129 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.442,853,479 - 3,565,666 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.142,853,478 - 3,565,666 (-)NCBI
Celera42,039,300 - 2,691,360 (+)NCBICelera
Cytogenetic Map4q11NCBI
Dpp6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554917,326,138 - 8,168,270 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554917,325,720 - 8,167,949 (+)NCBIChiLan1.0ChiLan1.0
DPP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26190,320,559 - 191,318,987 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1742,330,825 - 43,329,253 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07145,356,340 - 146,492,773 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17157,635,454 - 158,220,345 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7157,635,828 - 158,220,345 (+)Ensemblpanpan1.1panPan2
DPP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11617,357,461 - 18,043,547 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1617,357,522 - 18,041,822 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1617,836,985 - 18,676,560 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01618,946,820 - 19,772,122 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1618,947,086 - 19,772,116 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11617,458,435 - 18,143,487 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01617,898,790 - 18,723,713 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01617,951,354 - 18,776,429 (+)NCBIUU_Cfam_GSD_1.0
Dpp6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051183,479,982 - 4,328,689 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365278,574,849 - 9,421,763 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365278,574,455 - 9,423,445 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPP6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl183,148,483 - 4,054,118 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1183,148,479 - 3,905,845 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2183,287,948 - 3,570,413 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DPP6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121121,882,842 - 123,035,787 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21122,441,548 - 123,035,792 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607218,290,133 - 19,155,278 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004860344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004860345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004860346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004860347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021240796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01070277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01070292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01002622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH171576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000014940   ⟹   ENSHGLP00000014795
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248002,725,253 - 3,145,437 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000014941   ⟹   ENSHGLP00000014796
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248002,727,002 - 3,585,409 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000014942   ⟹   ENSHGLP00000014797
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248002,727,002 - 3,471,690 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000014943   ⟹   ENSHGLP00000014798
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248002,727,002 - 3,332,220 (-)Ensembl
RefSeq Acc Id: XM_004860344   ⟹   XP_004860401
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248002,725,353 - 3,332,599 (-)NCBI
RefSeq Acc Id: XM_004860345   ⟹   XP_004860402
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248002,725,353 - 3,585,987 (-)NCBI
RefSeq Acc Id: XM_004860346   ⟹   XP_004860403
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248002,725,353 - 3,145,411 (-)NCBI
RefSeq Acc Id: XM_004860347   ⟹   XP_004860404
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248002,725,353 - 3,471,819 (-)NCBI
RefSeq Acc Id: XM_021240796   ⟹   XP_021096455
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248002,725,353 - 3,113,539 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004860402   ⟸   XM_004860345
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JWR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860404   ⟸   XM_004860347
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JWR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860401   ⟸   XM_004860344
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JWR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860403   ⟸   XM_004860346
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JWR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021096455   ⟸   XM_021240796
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JWR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014797   ⟸   ENSHGLT00000014942
RefSeq Acc Id: ENSHGLP00000014796   ⟸   ENSHGLT00000014941
RefSeq Acc Id: ENSHGLP00000014798   ⟸   ENSHGLT00000014943
RefSeq Acc Id: ENSHGLP00000014795   ⟸   ENSHGLT00000014940


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010566 Ensembl, ENTREZGENE
  ENSHGLG00100002890 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000014940 ENTREZGENE
  ENSHGLT00000014941 ENTREZGENE
  ENSHGLT00000014942 ENTREZGENE
  ENSHGLT00000014943 ENTREZGENE
  ENSHGLT00100003855 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
  Dipeptidylpeptidase IV, N-terminal domain UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/TrEMBL
  Peptidase_S9B_N UniProtKB/TrEMBL
NCBI Gene Dpp6 ENTREZGENE
PANTHER DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6 UniProtKB/TrEMBL
  PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED UniProtKB/TrEMBL
Pfam DPPIV_N UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/TrEMBL
Superfamily-SCOP DPP6 N-terminal domain-like UniProtKB/TrEMBL
  SSF53474 UniProtKB/TrEMBL
UniProt A0A0P6JWR0 ENTREZGENE, UniProtKB/TrEMBL