Srxn1 (sulfiredoxin 1) - Rat Genome Database

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Gene: Srxn1 (sulfiredoxin 1) Heterocephalus glaber
Analyze
Symbol: Srxn1
Name: sulfiredoxin 1
RGD ID: 18927512
Description: ENCODES a protein that exhibits oxidoreductase activity, acting on a sulfur group of donors (ortholog); INVOLVED IN response to oxidative stress (ortholog); ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 1 (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sulfiredoxin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247411,724,554 - 1,730,059 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Srxn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247411,724,554 - 1,730,059 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SRXN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3820646,615 - 653,200 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl20646,615 - 653,200 (-)EnsemblGRCh38hg38GRCh38
GRCh3720627,259 - 633,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3620575,259 - 581,890 (-)NCBINCBI36Build 36hg18NCBI36
Build 3420575,269 - 581,890NCBI
Celera20722,084 - 728,715 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef20578,569 - 585,325 (-)NCBIHuRef
CHM1_120627,286 - 634,040 (-)NCBICHM1_1
T2T-CHM13v2.020690,889 - 697,474 (-)NCBIT2T-CHM13v2.0
Srxn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392151,946,738 - 151,953,296 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2151,947,436 - 151,953,296 (+)EnsemblGRCm39 Ensembl
GRCm382152,105,524 - 152,111,376 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,105,516 - 152,111,376 (+)EnsemblGRCm38mm10GRCm38
MGSCv372151,931,466 - 151,937,089 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362151,797,171 - 151,802,794 (+)NCBIMGSCv36mm8
Celera2157,921,724 - 157,927,347 (+)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.83NCBI
Srxn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,064,812 - 161,070,372 (+)NCBIGRCr8
mRatBN7.23140,604,490 - 140,610,050 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3140,599,608 - 140,628,448 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3144,508,993 - 144,514,553 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,092,812 - 153,098,372 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03150,833,296 - 150,838,855 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03147,608,850 - 147,614,410 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,609,095 - 147,632,801 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03153,957,677 - 153,963,237 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43142,457,352 - 142,462,725 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13142,357,865 - 142,386,609 (+)NCBI
Celera3139,357,182 - 139,362,742 (+)NCBICelera
Cytogenetic Map3q41NCBI
Srxn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955597483,358 - 487,555 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955597483,358 - 487,555 (-)NCBIChiLan1.0ChiLan1.0
SRXN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1201,732,942 - 1,739,638 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v020855,951 - 862,640 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.120625,376 - 631,950 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl20625,376 - 631,950 (-)Ensemblpanpan1.1panPan2
SRXN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,232,608 - 20,238,838 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2420,232,607 - 20,237,154 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2419,885,276 - 19,891,640 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02420,923,866 - 20,930,218 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2420,923,866 - 20,930,153 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,199,129 - 20,205,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02420,304,875 - 20,311,233 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02420,735,939 - 20,742,311 (+)NCBIUU_Cfam_GSD_1.0
Srxn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640169,441,639 - 169,484,737 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648517,873,286 - 17,877,783 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648517,873,283 - 17,879,746 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRXN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1734,582,440 - 34,589,300 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11734,582,377 - 34,589,308 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,382,631 - 39,389,562 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SRXN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1255,866,050 - 55,870,568 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660788,080,707 - 8,087,095 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004840636   ⟹   XP_004840693
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247411,724,554 - 1,730,059 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004840693 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein JAO03317 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004840693   ⟸   XM_004840636
- UniProtKB: A0A0P6JFM5 (UniProtKB/TrEMBL),   G5C6M5 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Gene3D-CATH Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain UniProtKB/TrEMBL
InterPro ParB/Sulfiredoxin_dom UniProtKB/TrEMBL
  ParB/Sulfiredoxin_sf UniProtKB/TrEMBL
  Sulfiredoxin UniProtKB/TrEMBL
KEGG Report hgl:101726463 UniProtKB/TrEMBL
NCBI Gene Srxn1 ENTREZGENE
PANTHER PTHR21348 UniProtKB/TrEMBL
  SULFIREDOXIN-1 UniProtKB/TrEMBL
Pfam ParBc UniProtKB/TrEMBL
PIRSF Sulfiredoxin UniProtKB/TrEMBL
SMART ParB UniProtKB/TrEMBL
Superfamily-SCOP SSF110849 UniProtKB/TrEMBL
UniProt A0A0P6JFM5 ENTREZGENE, UniProtKB/TrEMBL
  G5C6M5 ENTREZGENE, UniProtKB/TrEMBL