Mfsd1 (major facilitator superfamily domain containing 1) - Rat Genome Database

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Gene: Mfsd1 (major facilitator superfamily domain containing 1) Heterocephalus glaber
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Symbol: Mfsd1
Name: major facilitator superfamily domain containing 1
RGD ID: 18927432
Description: ENCODES a protein that exhibits dipeptide uniporter activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN dipeptide transmembrane transport from lysosomal lumen to cytosol (ortholog); protein localization to lysosome (ortholog); protein stabilization (ortholog); FOUND IN lysosomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Major facilitator superfamily domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473036,502,209 - 36,525,748 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473036,502,186 - 36,525,331 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
lysosomal membrane  (IEA,ISO)
lysosome  (IEA)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mfsd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473036,502,209 - 36,525,748 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473036,502,186 - 36,525,331 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MFSD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383158,802,054 - 158,829,716 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3158,732,198 - 158,829,719 (+)EnsemblGRCh38hg38GRCh38
GRCh373158,519,843 - 158,547,505 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363160,002,606 - 160,030,198 (+)NCBINCBI36Build 36hg18NCBI36
Build 343160,002,613 - 160,030,206NCBI
Celera3156,942,471 - 156,970,268 (+)NCBICelera
Cytogenetic Map3q25.32NCBI
HuRef3155,915,581 - 155,943,367 (+)NCBIHuRef
CHM1_13158,482,624 - 158,510,416 (+)NCBICHM1_1
T2T-CHM13v2.03161,575,980 - 161,603,601 (+)NCBIT2T-CHM13v2.0
Mfsd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39367,490,101 - 67,511,564 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl367,490,074 - 67,511,570 (+)EnsemblGRCm39 Ensembl
GRCm38367,582,768 - 67,604,231 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl367,582,741 - 67,604,237 (+)EnsemblGRCm38mm10GRCm38
MGSCv37367,386,690 - 67,408,153 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36367,670,697 - 67,692,160 (+)NCBIMGSCv36mm8
Celera367,709,416 - 67,730,879 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map331.07NCBI
Mfsd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82154,156,167 - 154,176,209 (+)NCBIGRCr8
mRatBN7.22151,846,130 - 151,866,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2151,846,146 - 151,867,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2158,963,053 - 158,983,289 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02157,013,548 - 157,033,784 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02151,646,296 - 151,666,532 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02164,747,655 - 164,767,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2164,747,677 - 164,767,682 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02184,095,514 - 184,115,522 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42157,432,951 - 157,452,956 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12157,382,939 - 157,400,624 (+)NCBI
Celera2146,215,790 - 146,235,853 (+)NCBICelera
Cytogenetic Map2q32NCBI
Mfsd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554489,536,549 - 9,561,661 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554489,536,613 - 9,557,846 (+)NCBIChiLan1.0ChiLan1.0
MFSD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,742,121 - 156,818,814 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13156,679,244 - 156,820,488 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03155,758,133 - 155,899,272 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13163,878,611 - 163,946,103 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3163,878,833 - 163,903,955 (+)Ensemblpanpan1.1panPan2
MFSD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13425,069,701 - 25,094,196 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3425,069,696 - 25,092,386 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3429,159,099 - 29,183,659 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03425,012,255 - 25,036,853 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3425,012,238 - 25,036,848 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13425,050,102 - 25,074,425 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03425,012,792 - 25,037,357 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03425,255,267 - 25,279,836 (+)NCBIUU_Cfam_GSD_1.0
Mfsd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560284,321,103 - 84,341,152 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365195,392,777 - 5,412,856 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365195,392,820 - 5,412,847 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MFSD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1398,592,370 - 98,615,523 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11398,592,344 - 98,615,061 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213107,004,118 - 107,049,836 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MFSD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11531,995,285 - 32,043,708 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1532,016,368 - 32,043,586 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660414,579,860 - 4,607,106 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000023914   ⟹   ENSHGLP00000023696
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473036,502,209 - 36,525,748 (+)Ensembl
RefSeq Acc Id: XM_004834519   ⟹   XP_004834576
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473036,502,187 - 36,525,331 (+)NCBI
RefSeq Acc Id: XM_004834520   ⟹   XP_004834577
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473036,502,186 - 36,523,145 (+)NCBI
RefSeq Acc Id: XM_021253625   ⟹   XP_021109284
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473036,502,386 - 36,525,331 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004834576 (Get FASTA)   NCBI Sequence Viewer  
  XP_004834577 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109284 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB13369 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023696
  ENSHGLP00100058254
RefSeq Acc Id: XP_004834577   ⟸   XM_004834520
- Peptide Label: isoform X2
- UniProtKB: G5BVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834576   ⟸   XM_004834519
- Peptide Label: isoform X1
- UniProtKB: G5BVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109284   ⟸   XM_021253625
- Peptide Label: isoform X3
Ensembl Acc Id: ENSHGLP00000023696   ⟸   ENSHGLT00000023914


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016907 Ensembl, ENTREZGENE
  ENSHGLG00100015811 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000023914 ENTREZGENE
  ENSHGLT00100048503 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  MFSD1 UniProtKB/TrEMBL
KEGG Report hgl:101698383 UniProtKB/TrEMBL
NCBI Gene Mfsd1 ENTREZGENE
PANTHER MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0AAX6SKT4_HETGA UniProtKB/TrEMBL
  G5BVQ9 ENTREZGENE, UniProtKB/TrEMBL