Prim1 (DNA primase subunit 1) - Rat Genome Database

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Gene: Prim1 (DNA primase subunit 1) Heterocephalus glaber
Analyze
Symbol: Prim1
Name: DNA primase subunit 1
RGD ID: 18926906
Description: ENCODES a protein that exhibits magnesium ion binding (ortholog); ribonucleotide binding (ortholog); zinc ion binding (ortholog); INVOLVED IN DNA replication initiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); primary ovarian insufficiency (ortholog); PRIMORDIAL DWARFISM-IMMUNODEFICIENCY-LIPODYSTROPHY SYNDROME (ortholog); FOUND IN alpha DNA polymerase:primase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA primase small subunit; primase (DNA) subunit 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,289,391 - 11,316,958 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,288,654 - 11,312,401 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Prim1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,289,391 - 11,316,958 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,288,654 - 11,312,401 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PRIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,731,580 - 56,752,323 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,730,438 - 56,752,374 (-)EnsemblGRCh38hg38GRCh38
GRCh371257,125,364 - 57,146,107 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,411,631 - 55,432,413 (-)NCBINCBI36Build 36hg18NCBI36
Build 341255,411,632 - 55,432,413NCBI
Celera1256,779,329 - 56,800,102 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,164,017 - 54,185,223 (-)NCBIHuRef
CHM1_11257,092,951 - 57,113,728 (-)NCBICHM1_1
T2T-CHM13v2.01256,699,510 - 56,720,267 (-)NCBIT2T-CHM13v2.0
Prim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,851,084 - 127,865,899 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,851,041 - 127,865,906 (+)EnsemblGRCm39 Ensembl
GRCm3810128,015,215 - 128,030,030 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,015,168 - 128,030,037 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,452,271 - 127,467,086 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,418,164 - 127,432,979 (+)NCBIMGSCv36mm8
Celera10130,410,422 - 130,425,144 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.39NCBI
Prim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,031,436 - 1,047,134 (+)NCBIGRCr8
mRatBN7.27446,342 - 462,526 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7431,805 - 462,526 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,205,126 - 3,220,740 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,081,138 - 5,096,753 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,379,312 - 5,394,371 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,435,524 - 2,451,169 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,435,553 - 2,451,165 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,415,106 - 2,430,940 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,293,137 - 1,323,029 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,293,147 - 1,321,776 (+)NCBI
Celera7325,353 - 341,972 (+)NCBICelera
Cytogenetic Map7q11NCBI
Prim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,275,517 - 4,294,257 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554584,265,500 - 4,294,329 (-)NCBIChiLan1.0ChiLan1.0
PRIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,570,526 - 37,594,933 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,567,295 - 37,591,702 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,155,541 - 32,176,363 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,408,929 - 32,428,734 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,408,929 - 32,428,734 (+)Ensemblpanpan1.1panPan2
PRIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110951,888 - 975,966 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,016,706 - 1,040,803 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010963,062 - 987,154 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10963,379 - 987,127 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110940,115 - 964,262 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,182,031 - 1,206,116 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,306,679 - 1,330,830 (-)NCBIUU_Cfam_GSD_1.0
Prim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,815,995 - 57,836,332 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,036,777 - 1,054,108 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,033,921 - 1,054,203 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,062,989 - 22,089,436 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,064,248 - 22,089,441 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,800,887 - 23,824,231 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,676,890 - 52,699,337 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,674,602 - 52,699,294 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037193,277,385 - 193,299,812 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000007508   ⟹   ENSHGLP00000007423
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462480211,289,391 - 11,316,958 (+)Ensembl
RefSeq Acc Id: XM_004861273   ⟹   XP_004861330
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480211,288,681 - 11,312,401 (+)NCBI
RefSeq Acc Id: XM_021241493   ⟹   XP_021097152
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480211,288,658 - 11,312,401 (+)NCBI
RefSeq Acc Id: XR_002388280
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480211,288,654 - 11,312,401 (+)NCBI
RefSeq Acc Id: XR_002388281
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480211,288,658 - 11,309,676 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004861330 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097152 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000007423
GenBank Protein JAO00650 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021097152   ⟸   XM_021241493
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004861330   ⟸   XM_004861273
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JHQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000007423   ⟸   ENSHGLT00000007508


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005406 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000007508 ENTREZGENE
Gene3D-CATH DNA primase, PRIM domain UniProtKB/TrEMBL
InterPro DNA_primase_S UniProtKB/TrEMBL
  DNA_primase_ssu_euk/arc UniProtKB/TrEMBL
KEGG Report hgl:101700362 UniProtKB/TrEMBL
NCBI Gene Prim1 ENTREZGENE
PANTHER DNA PRIMASE SMALL SUBUNIT UniProtKB/TrEMBL
  PTHR10536 UniProtKB/TrEMBL
Pfam DNA_primase_S UniProtKB/TrEMBL
Superfamily-SCOP Prim-pol domain UniProtKB/TrEMBL
UniProt A0A0P6JHQ9 ENTREZGENE, UniProtKB/TrEMBL