Klhl20 (kelch like family member 20) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Klhl20 (kelch like family member 20) Heterocephalus glaber
Analyze
Symbol: Klhl20
Name: kelch like family member 20
RGD ID: 18926427
Description: ENCODES a protein that exhibits type II interferon binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN Golgi to endosome transport (ortholog); negative regulation of apoptotic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); antithrombin III deficiency (ortholog); autoimmune lymphoproliferative syndrome (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kelch-like protein 20
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247718,068,522 - 8,117,329 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Klhl20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247718,068,522 - 8,117,329 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KLHL20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381173,714,981 - 173,786,692 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1173,714,941 - 173,786,692 (+)EnsemblGRCh38hg38GRCh38
GRCh371173,684,120 - 173,755,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,950,703 - 172,022,463 (+)NCBINCBI36Build 36hg18NCBI36
Build 341170,415,736 - 170,487,495NCBI
Celera1146,793,483 - 146,865,313 (+)NCBICelera
Cytogenetic Map1q25.1NCBI
HuRef1144,908,412 - 144,980,589 (+)NCBIHuRef
CHM1_11175,106,512 - 175,178,272 (+)NCBICHM1_1
T2T-CHM13v2.01173,064,952 - 173,144,852 (+)NCBIT2T-CHM13v2.0
Klhl20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,915,945 - 160,959,078 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,915,945 - 160,959,081 (-)EnsemblGRCm39 Ensembl
GRCm381161,088,375 - 161,131,508 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,088,375 - 161,131,511 (-)EnsemblGRCm38mm10GRCm38
MGSCv371163,018,509 - 163,061,610 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361162,925,055 - 162,968,156 (-)NCBIMGSCv36mm8
Celera1163,529,622 - 163,575,184 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map169.75NCBI
Klhl20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81375,896,802 - 75,941,724 (-)NCBIGRCr8
mRatBN7.21373,363,451 - 73,408,293 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1373,363,455 - 73,408,337 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1375,957,572 - 76,000,750 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01377,241,750 - 77,284,981 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01374,501,649 - 74,544,879 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01378,912,361 - 78,957,226 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1378,912,361 - 78,957,212 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01383,806,856 - 83,851,835 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41376,655,800 - 76,700,630 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11376,669,986 - 76,714,795 (-)NCBI
Celera1373,151,653 - 73,196,612 (-)NCBICelera
Cytogenetic Map13q22NCBI
Klhl20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540613,891,571 - 13,938,964 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540613,891,589 - 13,938,964 (+)NCBIChiLan1.0ChiLan1.0
KLHL20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2175,933,888 - 76,010,859 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1175,607,955 - 75,684,925 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01149,232,858 - 149,303,357 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11152,937,823 - 153,008,239 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1152,937,835 - 153,008,239 (+)Ensemblpanpan1.1panPan2
KLHL20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1725,430,490 - 25,484,245 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl725,430,745 - 25,484,311 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha724,963,208 - 25,016,807 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0725,181,335 - 25,235,514 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl725,181,410 - 25,235,592 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1725,100,724 - 25,154,322 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0725,182,954 - 25,236,787 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0725,327,998 - 25,381,599 (-)NCBIUU_Cfam_GSD_1.0
Klhl20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934496,227,044 - 96,264,900 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648114,071,470 - 14,111,838 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648114,074,169 - 14,111,634 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9116,005,574 - 116,083,452 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19116,005,562 - 116,083,478 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29127,640,396 - 127,718,048 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12555,407,648 - 55,473,195 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2555,405,713 - 55,473,175 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605556,970,008 - 57,035,548 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004853416   ⟹   XP_004853473
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247718,068,522 - 8,117,329 (-)NCBI
RefSeq Acc Id: XM_004853417   ⟹   XP_004853474
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247718,068,522 - 8,117,100 (-)NCBI
RefSeq Acc Id: XM_021265408   ⟹   XP_021121067
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247718,068,522 - 8,108,854 (-)NCBI
RefSeq Acc Id: XR_002397846
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247718,068,522 - 8,108,860 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004853473 (Get FASTA)   NCBI Sequence Viewer  
  XP_004853474 (Get FASTA)   NCBI Sequence Viewer  
  XP_021121067 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014522
  ENSHGLP00000014523
  ENSHGLP00100009844
GenBank Protein JAO02311 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004853473   ⟸   XM_004853416
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JD30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853474   ⟸   XM_004853417
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JD30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121067   ⟸   XM_021265408
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010402 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100007304 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000014667 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00000014668 ENTREZGENE
  ENSHGLT00100009957 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
KEGG Report hgl:101725550 UniProtKB/TrEMBL
NCBI Gene Klhl20 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/TrEMBL
  KELCH-LIKE PROTEIN 20 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PRINTS KELCHREPEAT UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A0P6JD30 ENTREZGENE, UniProtKB/TrEMBL