Fig4 (FIG4 phosphoinositide 5-phosphatase) - Rat Genome Database

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Gene: Fig4 (FIG4 phosphoinositide 5-phosphatase) Heterocephalus glaber
Analyze
Symbol: Fig4
Name: FIG4 phosphoinositide 5-phosphatase
RGD ID: 18926409
Description: ENCODES a protein that exhibits phosphatidylinositol bisphosphate phosphatase activity (ortholog); phosphatidylinositol-3-phosphate phosphatase activity (ortholog); phosphatidylinositol-4-phosphate phosphatase activity (ortholog); INVOLVED IN locomotory behavior (ortholog); myelin assembly (ortholog); myelination (ortholog); PARTICIPATES IN inositol metabolic pathway; phosphoinositide metabolic pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); amyotrophic lateral sclerosis type 11 (ortholog); FOUND IN endosome membrane (ortholog); lipid droplet (ortholog); recycling endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FIG4 homolog, SAC1 lipid phosphatase domain containing; polyphosphoinositide phosphatase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462485029,362 - 156,346 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Fig4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462485029,362 - 156,346 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FIG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386109,691,296 - 109,825,426 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6109,690,609 - 109,878,098 (+)EnsemblGRCh38hg38GRCh38
GRCh376110,012,499 - 110,146,629 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366110,119,161 - 110,253,327 (+)NCBINCBI36Build 36hg18NCBI36
Build 346110,119,160 - 110,253,327NCBI
Celera6110,759,045 - 110,893,292 (+)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6107,578,606 - 107,713,071 (+)NCBIHuRef
CHM1_16110,275,404 - 110,409,874 (+)NCBICHM1_1
T2T-CHM13v2.06110,869,350 - 111,003,788 (+)NCBIT2T-CHM13v2.0
Fig4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391041,064,168 - 41,179,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1041,064,168 - 41,179,256 (-)EnsemblGRCm39 Ensembl
GRCm381041,188,172 - 41,303,241 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1041,188,172 - 41,303,260 (-)EnsemblGRCm38mm10GRCm38
MGSCv371040,907,978 - 41,023,047 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361040,876,587 - 40,991,656 (-)NCBIMGSCv36mm8
Celera1042,083,412 - 42,197,996 (-)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1022.08NCBI
Fig4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82046,183,225 - 46,306,686 (-)NCBIGRCr8
mRatBN7.22044,600,603 - 44,724,047 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2044,600,603 - 44,723,844 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2046,388,086 - 46,511,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02046,047,227 - 46,170,581 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02046,772,600 - 46,893,206 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02045,922,806 - 46,044,754 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2045,922,806 - 46,044,738 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02047,625,556 - 47,747,494 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42045,123,352 - 45,248,795 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12045,146,775 - 45,222,780 (-)NCBI
Celera2045,399,685 - 45,522,856 (-)NCBICelera
Cytogenetic Map20q12NCBI
Fig4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554113,135,752 - 3,217,891 (-)NCBIChiLan1.0ChiLan1.0
FIG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25129,701,209 - 129,836,807 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16127,589,237 - 127,723,686 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06107,495,637 - 107,631,201 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16111,539,937 - 111,673,894 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6111,539,937 - 111,673,894 (+)Ensemblpanpan1.1panPan2
FIG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11266,508,801 - 66,632,830 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1266,509,431 - 66,632,822 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1266,329,148 - 66,452,527 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01267,393,792 - 67,518,028 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1267,394,350 - 67,518,026 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11266,742,283 - 66,865,882 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01266,591,834 - 66,714,914 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01266,863,026 - 66,986,428 (+)NCBIUU_Cfam_GSD_1.0
Fig4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946101,462,042 - 101,567,353 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365645,736,873 - 5,842,722 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365645,736,908 - 5,842,210 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl175,694,151 - 75,847,528 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1175,694,151 - 75,847,021 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2185,452,466 - 85,539,950 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2184,995,954 - 85,027,999 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FIG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11364,054,000 - 64,186,800 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1364,054,002 - 64,186,714 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604036,346,233 - 36,489,346 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004868807   ⟹   XP_004868864
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462485029,362 - 156,346 (+)NCBI
RefSeq Acc Id: XM_004868808   ⟹   XP_004868865
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462485029,362 - 156,346 (+)NCBI
RefSeq Acc Id: XM_004868809   ⟹   XP_004868866
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462485029,363 - 156,346 (+)NCBI
RefSeq Acc Id: XM_021247624   ⟹   XP_021103283
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462485029,362 - 156,346 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004868864 (Get FASTA)   NCBI Sequence Viewer  
  XP_004868865 (Get FASTA)   NCBI Sequence Viewer  
  XP_004868866 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103283 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002422
GenBank Protein JAN97162 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004868864   ⟸   XM_004868807
- Peptide Label: isoform X1
- UniProtKB: A0A0P6IYL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103283   ⟸   XM_021247624
- Peptide Label: isoform X2
- UniProtKB: A0A0P6IYL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868865   ⟸   XM_004868808
- Peptide Label: isoform X3
- UniProtKB: A0A0P6IYL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868866   ⟸   XM_004868809
- Peptide Label: isoform X4
- UniProtKB: A0A0P6IYL0 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001833 ENTREZGENE
Ensembl Transcript ENSHGLT00000002473 ENTREZGENE
InterPro Fig4-like UniProtKB/TrEMBL
  SAC_dom UniProtKB/TrEMBL
NCBI Gene Fig4 ENTREZGENE
PANTHER POLYPHOSPHOINOSITIDE PHOSPHATASE UniProtKB/TrEMBL
  PTHR45738 UniProtKB/TrEMBL
Pfam Syja_N UniProtKB/TrEMBL
PROSITE SAC UniProtKB/TrEMBL
UniProt A0A0P6IYL0 ENTREZGENE, UniProtKB/TrEMBL