Tsr2 (TSR2 ribosome maturation factor) - Rat Genome Database

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Gene: Tsr2 (TSR2 ribosome maturation factor) Heterocephalus glaber
Analyze
Symbol: Tsr2
Name: TSR2 ribosome maturation factor
RGD ID: 18925964
Description: INVOLVED IN maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (inferred); rRNA processing (inferred); ASSOCIATED WITH Aarskog syndrome (ortholog); autistic disorder (ortholog); Cornelia de Lange syndrome 2 (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pre-rRNA-processing protein TSR2 homolog; Pre-rRNA-processing protein TSR2-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249092,310,718 - 2,315,538 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249092,311,494 - 2,316,358 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Tsr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249092,310,718 - 2,315,538 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249092,311,494 - 2,316,358 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TSR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X54,440,404 - 54,448,032 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX54,440,404 - 54,448,032 (+)EnsemblGRCh38hg38GRCh38
GRCh37X54,466,837 - 54,474,465 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,483,578 - 54,488,455 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX58,299,414 - 58,304,291 (+)NCBICelera
Cytogenetic MapXp11.22NCBI
HuRefX51,518,075 - 51,522,307 (+)NCBIHuRef
CHM1_1X54,457,507 - 54,462,384 (+)NCBICHM1_1
T2T-CHM13v2.0X53,731,260 - 53,738,888 (+)NCBIT2T-CHM13v2.0
Tsr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X149,870,090 - 149,879,539 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX149,870,090 - 149,879,539 (-)EnsemblGRCm39 Ensembl
GRCm38X151,087,094 - 151,096,543 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX151,087,094 - 151,096,543 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X147,521,637 - 147,531,086 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X146,428,025 - 146,437,234 (-)NCBIMGSCv36mm8
CeleraX133,307,018 - 133,317,146 (+)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Tsr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X23,507,141 - 23,515,711 (-)NCBIGRCr8
mRatBN7.2X20,064,102 - 20,072,673 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX20,064,103 - 20,072,620 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX17,502,402 - 17,510,917 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X22,612,665 - 22,621,180 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X20,593,349 - 20,601,866 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X20,141,406 - 20,146,082 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX20,144,432 - 20,232,639 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X20,968,908 - 20,977,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX20,321,354 - 20,329,877 (-)NCBICelera
Cytogenetic MapXq12NCBI
Tsr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554751,698,136 - 1,703,404 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554751,698,926 - 1,703,404 (+)NCBIChiLan1.0ChiLan1.0
TSR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X55,829,012 - 55,833,962 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X55,832,617 - 55,837,566 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X46,643,659 - 46,648,829 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X54,875,679 - 54,883,324 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX54,875,696 - 54,880,809 (+)Ensemblpanpan1.1panPan2
TSR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X46,189,810 - 46,194,949 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX46,189,870 - 46,296,966 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX37,578,758 - 37,583,898 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X46,511,181 - 46,516,318 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX46,511,246 - 46,516,313 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X46,008,993 - 46,014,130 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X46,459,373 - 46,464,505 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X46,526,670 - 46,531,808 (+)NCBIUU_Cfam_GSD_1.0
Tsr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X39,010,776 - 39,015,724 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367511,350,481 - 1,358,110 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367511,350,542 - 1,355,449 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX47,186,643 - 47,192,452 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X47,186,610 - 47,192,465 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X53,043,987 - 53,049,415 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X50,532,958 - 50,555,179 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660864,515,626 - 4,523,216 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000002989   ⟹   ENSHGLP00000002935
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249092,310,718 - 2,315,538 (+)Ensembl
RefSeq Acc Id: XM_004873533   ⟹   XP_004873590
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249092,311,494 - 2,316,358 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004873590 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB07876 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002935
Reference Protein Sequences
RefSeq Acc Id: XP_004873590   ⟸   XM_004873533
- UniProtKB: G5BF15 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000002935   ⟸   ENSHGLT00000002989


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002188 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000002989 ENTREZGENE
InterPro Pre-rRNA_process_TSR2 UniProtKB/TrEMBL
NCBI Gene Tsr2 ENTREZGENE
PANTHER PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam WGG UniProtKB/TrEMBL
UniProt G5BF15 ENTREZGENE, UniProtKB/TrEMBL