Vbp1 (VHL binding protein 1) - Rat Genome Database

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Gene: Vbp1 (VHL binding protein 1) Heterocephalus glaber
Analyze
Symbol: Vbp1
Name: VHL binding protein 1
RGD ID: 18924917
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); unfolded protein binding (ortholog); INVOLVED IN negative regulation of amyloid fibril formation (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog); autistic disorder (ortholog); Barth syndrome (ortholog); FOUND IN cytosol (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: prefoldin subunit 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462496393,135 - 129,198 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462496394,482 - 129,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Vbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462496393,135 - 129,198 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462496394,482 - 129,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
VBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X155,197,007 - 155,239,841 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX155,197,007 - 155,239,841 (+)EnsemblGRCh38hg38GRCh38
GRCh37X154,425,284 - 154,468,122 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X154,097,744 - 154,121,292 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X154,008,253 - 154,031,800NCBI
CeleraX154,603,029 - 154,626,576 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,988,694 - 143,012,102 (+)NCBIHuRef
CHM1_1X154,356,371 - 154,379,765 (+)NCBICHM1_1
T2T-CHM13v2.0X153,433,306 - 153,476,144 (+)NCBIT2T-CHM13v2.0
Vbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X74,557,903 - 74,578,552 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX74,557,905 - 74,578,548 (+)EnsemblGRCm39 Ensembl
GRCm38X75,514,297 - 75,534,946 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX75,514,299 - 75,534,942 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X72,759,636 - 72,780,285 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X71,767,074 - 71,787,619 (+)NCBIMGSCv36mm8
CeleraX66,916,302 - 66,937,018 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.25NCBI
Vbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
UTH_Rnor_SHR_UtxY2,110,980 - 2,128,847 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X158,486,589 - 158,504,456 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0Y278,442 - 296,310 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01148,425,046 - 148,443,505 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1148,424,977 - 148,443,358 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01154,704,249 - 154,723,093 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1137,517,154 - 137,532,514 (-)NCBICelera
Cytogenetic Map1q31NCBI
Vbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955594447,750 - 477,796 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955594450,048 - 477,504 (-)NCBIChiLan1.0ChiLan1.0
VBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X155,184,268 - 155,208,081 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X155,187,876 - 155,211,689 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X144,685,548 - 144,709,136 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X154,504,795 - 154,547,773 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX154,504,795 - 154,547,773 (+)Ensemblpanpan1.1panPan2
VBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X123,210,965 - 123,231,847 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX123,203,722 - 123,231,091 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX108,198,258 - 108,219,138 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X126,332,496 - 126,353,396 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX126,325,242 - 126,353,392 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X122,080,310 - 122,101,180 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X124,602,728 - 124,623,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X124,323,269 - 124,343,955 (+)NCBIUU_Cfam_GSD_1.0
Vbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X120,075,121 - 120,109,719 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936927433,551 - 469,331 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936927433,598 - 468,191 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX125,480,808 - 125,506,771 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X125,485,357 - 125,506,781 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X142,924,188 - 142,945,608 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X129,487,543 - 129,510,301 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606567,467,011 - 67,489,809 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001340   ⟹   ENSHGLP00000001298
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462496393,135 - 129,198 (-)Ensembl
RefSeq Acc Id: XM_004875174   ⟹   XP_004875231
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462496394,482 - 129,223 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004875231 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001298
  ENSHGLP00000045057
  ENSHGLP00100035014
GenBank Protein JAN96692 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004875231   ⟸   XM_004875174
- UniProtKB: A0A0P6J093 (UniProtKB/TrEMBL),   G5C3W1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000001298   ⟸   ENSHGLT00000001340


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001012 Ensembl, ENTREZGENE
  ENSHGLG00000044108 UniProtKB/TrEMBL
  ENSHGLG00100000150 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000001340 ENTREZGENE
  ENSHGLT00000060288 UniProtKB/TrEMBL
  ENSHGLT00100072646 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.370 UniProtKB/TrEMBL
InterPro PFD3 UniProtKB/TrEMBL
  Prefoldin UniProtKB/TrEMBL
  Prefoldin_subunit_alpha UniProtKB/TrEMBL
KEGG Report hgl:101719175 UniProtKB/TrEMBL
NCBI Gene Vbp1 ENTREZGENE
PANTHER PREFOLDIN SUBUNIT 3 UniProtKB/TrEMBL
  PTHR12409 UniProtKB/TrEMBL
Pfam Prefoldin UniProtKB/TrEMBL
PIRSF Prefoldin_subunit_3 UniProtKB/TrEMBL
Superfamily-SCOP Prefoldin UniProtKB/TrEMBL
UniProt A0A0P6J093 ENTREZGENE, UniProtKB/TrEMBL
  G5C3W1 ENTREZGENE, UniProtKB/TrEMBL