Gramd2a (GRAM domain containing 2A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Gramd2a (GRAM domain containing 2A) Heterocephalus glaber
Analyze
Symbol: Gramd2a
Name: GRAM domain containing 2A
RGD ID: 18924855
Description: ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); INVOLVED IN endoplasmic reticulum-plasma membrane tethering (inferred); regulation of store-operated calcium entry (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Tay-Sachs disease (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GRAM domain containing 2; GRAM domain-containing protein 2; Gramd2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247811,852,433 - 1,858,359 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247811,825,123 - 1,860,695 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Gramd2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247811,852,433 - 1,858,359 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247811,825,123 - 1,860,695 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GRAMD2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381572,159,806 - 72,197,787 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1572,159,806 - 72,197,787 (-)EnsemblGRCh38hg38GRCh38
GRCh371572,452,147 - 72,490,128 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361570,239,202 - 70,277,180 (-)NCBINCBI36Build 36hg18NCBI36
Celera1549,338,482 - 49,376,472 (-)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1549,282,391 - 49,320,733 (-)NCBIHuRef
CHM1_11572,570,298 - 72,608,273 (-)NCBICHM1_1
T2T-CHM13v2.01569,976,533 - 70,014,515 (-)NCBIT2T-CHM13v2.0
Gramd2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39959,587,116 - 59,626,156 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl959,587,427 - 59,626,157 (+)EnsemblGRCm39 Ensembl
GRCm38959,679,833 - 59,718,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl959,680,144 - 59,718,874 (+)EnsemblGRCm38mm10GRCm38
MGSCv37959,555,571 - 59,564,231 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36959,505,770 - 59,514,430 (+)NCBIMGSCv36mm8
Celera956,935,077 - 56,943,737 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.05NCBI
Gramd2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8868,975,529 - 69,013,575 (+)NCBIGRCr8
mRatBN7.2860,079,744 - 60,117,788 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl860,080,338 - 60,115,842 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx865,614,895 - 65,639,991 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0863,887,816 - 63,912,914 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0861,757,271 - 61,782,369 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0864,503,058 - 64,539,149 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl864,531,594 - 64,539,367 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0864,266,714 - 64,303,816 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4863,536,874 - 63,544,192 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera859,522,697 - 59,560,686 (+)NCBICelera
Cytogenetic Map8q24NCBI
Gramd2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554504,954,223 - 4,960,280 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554504,936,357 - 4,960,643 (+)NCBIChiLan1.0ChiLan1.0
GRAMD2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21661,424,978 - 61,462,105 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11565,589,194 - 65,626,323 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01551,111,249 - 51,148,379 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11569,874,593 - 69,912,241 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1569,874,593 - 69,912,241 (-)Ensemblpanpan1.1panPan2
GRAMD2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13035,679,571 - 35,711,642 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3035,681,713 - 35,713,054 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3035,616,627 - 35,648,632 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03035,883,954 - 35,916,247 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3035,886,120 - 35,916,212 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13035,837,346 - 35,869,289 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03035,865,209 - 35,897,197 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03036,120,073 - 36,152,105 (-)NCBIUU_Cfam_GSD_1.0
Gramd2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640113,702,443 - 113,739,942 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647131,550,406 - 31,587,981 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647131,550,506 - 31,588,377 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100627175
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11169,638,097 - 169,664,774 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GRAMD2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12611,255,629 - 11,299,132 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2611,256,792 - 11,300,174 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048130,275,502 - 130,316,723 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000007383   ⟹   ENSHGLP00000007298
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247811,852,433 - 1,858,359 (+)Ensembl
RefSeq Acc Id: XM_004855536   ⟹   XP_004855593
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,843,786 - 1,860,693 (+)NCBI
RefSeq Acc Id: XM_004855537   ⟹   XP_004855594
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,832,781 - 1,860,693 (+)NCBI
RefSeq Acc Id: XM_013076130   ⟹   XP_012931584
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,852,599 - 1,860,694 (+)NCBI
RefSeq Acc Id: XM_021236978   ⟹   XP_021092637
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,851,780 - 1,860,694 (+)NCBI
RefSeq Acc Id: XM_021236980   ⟹   XP_021092639
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,843,798 - 1,860,694 (+)NCBI
RefSeq Acc Id: XM_021236981   ⟹   XP_021092640
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,825,123 - 1,860,694 (+)NCBI
RefSeq Acc Id: XM_021236982   ⟹   XP_021092641
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,851,776 - 1,860,695 (+)NCBI
RefSeq Acc Id: XP_021092640   ⟸   XM_021236981
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PND5 (UniProtKB/TrEMBL),   G5C6U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855594   ⟸   XM_004855537
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PND5 (UniProtKB/TrEMBL),   G5C6U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855593   ⟸   XM_004855536
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PND5 (UniProtKB/TrEMBL),   G5C6U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092639   ⟸   XM_021236980
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PND5 (UniProtKB/TrEMBL),   G5C6U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092641   ⟸   XM_021236982
- Peptide Label: isoform X4
- UniProtKB: A0AAX6R6X5 (UniProtKB/TrEMBL),   G5C6U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092637   ⟸   XM_021236978
- Peptide Label: isoform X1
- UniProtKB: A0AAX6R572 (UniProtKB/TrEMBL),   G5C6U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012931584   ⟸   XM_013076130
- Peptide Label: isoform X3
- UniProtKB: A0AAX6R1F1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000007298   ⟸   ENSHGLT00000007383


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005317 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000007383 ENTREZGENE
Gene3D-CATH Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) UniProtKB/TrEMBL
InterPro GRAM UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  RAMD2A UniProtKB/TrEMBL
NCBI Gene Gramd2a ENTREZGENE
PANTHER GRAM DOMAIN-CONTAINING PROTEIN 2A UniProtKB/TrEMBL
  GRAM DOMAIN-CONTAINING PROTEIN 2A UniProtKB/TrEMBL
Pfam GRAM UniProtKB/TrEMBL
SMART GRAM UniProtKB/TrEMBL
UniProt A0AAX6PND5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R1F1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R572 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R6X5 ENTREZGENE, UniProtKB/TrEMBL
  G5C6U3 ENTREZGENE, UniProtKB/TrEMBL