Lrrc57 (leucine rich repeat containing 57) - Rat Genome Database

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Gene: Lrrc57 (leucine rich repeat containing 57) Heterocephalus glaber
Analyze
Symbol: Lrrc57
Name: leucine rich repeat containing 57
RGD ID: 18924819
Description: ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Leucine-rich repeat-containing protein 57
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248049,648,956 - 9,656,754 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248049,648,956 - 9,656,464 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Lrrc57
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248049,648,956 - 9,656,754 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248049,648,956 - 9,656,464 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LRRC57
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381542,528,327 - 42,548,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1542,537,820 - 42,548,802 (-)EnsemblGRCh38hg38GRCh38
GRCh371542,830,027 - 42,840,991 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361540,622,014 - 40,628,292 (-)NCBINCBI36Build 36hg18NCBI36
Celera1519,602,426 - 19,608,708 (-)NCBICelera
Cytogenetic Map15q15.2NCBI
HuRef1519,682,473 - 19,688,755 (-)NCBIHuRef
CHM1_11542,953,162 - 42,959,444 (-)NCBICHM1_1
T2T-CHM13v2.01540,334,371 - 40,354,843 (-)NCBIT2T-CHM13v2.0
Lrrc57
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,434,719 - 120,439,989 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,434,719 - 120,440,001 (-)EnsemblGRCm39 Ensembl
GRCm382120,604,238 - 120,609,508 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2120,604,238 - 120,609,520 (-)EnsemblGRCm38mm10GRCm38
MGSCv372120,429,974 - 120,435,244 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362120,295,679 - 120,300,715 (-)NCBIMGSCv36mm8
Celera2121,757,029 - 121,762,300 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.37NCBI
Lrrc57
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,998,535 - 128,007,004 (-)NCBIGRCr8
mRatBN7.23107,544,786 - 107,553,256 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,547,405 - 107,553,256 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3111,222,226 - 111,228,070 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03119,817,799 - 119,823,643 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03117,478,192 - 117,484,036 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03112,365,936 - 112,371,787 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,365,938 - 112,385,528 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,370,057 - 112,371,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,912,832 - 118,918,683 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43107,365,961 - 107,371,816 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13107,262,390 - 107,268,061 (-)NCBI
Celera3106,454,979 - 106,460,831 (-)NCBICelera
Cytogenetic Map3q35NCBI
Lrrc57
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554169,230,362 - 9,237,799 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554169,230,362 - 9,237,799 (-)NCBIChiLan1.0ChiLan1.0
LRRC57
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21631,788,619 - 31,799,619 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11535,945,583 - 35,956,606 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01521,499,139 - 21,510,154 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11539,659,381 - 39,666,068 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1539,659,387 - 39,666,068 (-)Ensemblpanpan1.1panPan2
LRRC57
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1309,497,328 - 9,502,235 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha309,554,594 - 9,559,683 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0309,632,152 - 9,637,242 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl309,632,159 - 9,637,170 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1309,551,416 - 9,556,506 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0309,657,980 - 9,663,060 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0309,790,695 - 9,795,782 (-)NCBIUU_Cfam_GSD_1.0
Lrrc57
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,974,785 - 87,978,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364715,820,579 - 5,827,084 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364715,822,165 - 5,826,894 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC57
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1128,839,204 - 128,847,431 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11128,839,137 - 128,845,749 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21143,731,688 - 143,738,556 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC57
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12640,427,588 - 40,434,108 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2640,427,887 - 40,432,553 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048100,578,130 - 100,584,784 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000019258   ⟹   ENSHGLP00000019067
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248049,648,956 - 9,656,754 (-)Ensembl
RefSeq Acc Id: XM_004861659   ⟹   XP_004861716
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248049,648,956 - 9,656,464 (-)NCBI
RefSeq Acc Id: XM_021241770   ⟹   XP_021097429
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248049,651,027 - 9,656,383 (-)NCBI
RefSeq Acc Id: XM_021241771   ⟹   XP_021097430
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248049,648,956 - 9,656,441 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004861716 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097429 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097430 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10346 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019067
  ENSHGLP00100020308
GenBank Protein JAO02902 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004861716   ⟸   XM_004861659
- Peptide Label: isoform X1
- UniProtKB: G5BM32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097430   ⟸   XM_021241771
- Peptide Label: isoform X1
- UniProtKB: G5BM32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097429   ⟸   XM_021241770
- Peptide Label: isoform X2
Ensembl Acc Id: ENSHGLP00000019067   ⟸   ENSHGLT00000019258


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013663 Ensembl, ENTREZGENE
  ENSHGLG00100014986 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000019258 ENTREZGENE
  ENSHGLT00100020523 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRR_domain-containing UniProtKB/TrEMBL
KEGG Report hgl:101712449 UniProtKB/TrEMBL
NCBI Gene Lrrc57 ENTREZGENE
PANTHER NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE-RELATED UniProtKB/TrEMBL
  PTHR48051 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt G5BM32 ENTREZGENE, UniProtKB/TrEMBL