Nell2 (neural EGFL like 2) - Rat Genome Database

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Gene: Nell2 (neural EGFL like 2) Heterocephalus glaber
Analyze
Symbol: Nell2
Name: neural EGFL like 2
RGD ID: 18924276
Description: ENCODES a protein that exhibits heparin binding (ortholog); identical protein binding (ortholog); protein kinase C binding (ortholog); INVOLVED IN commissural neuron axon guidance (ortholog); development of secondary female sexual characteristics (ortholog); fertilization (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN dendrite (ortholog); extracellular region (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NEL-like 2; Protein kinase C-binding protein NELL2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248167,503,067 - 8,007,081 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248167,502,615 - 8,006,241 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Nell2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248167,503,067 - 8,007,081 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248167,502,615 - 8,006,241 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NELL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381244,508,275 - 44,921,848 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1244,508,275 - 44,921,848 (-)EnsemblGRCh38hg38GRCh38
GRCh371244,902,058 - 45,307,772 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361243,188,332 - 43,556,405 (-)NCBINCBI36Build 36hg18NCBI36
Build 341243,188,331 - 43,556,405NCBI
Celera1243,705,353 - 44,111,067 (-)NCBICelera
Cytogenetic Map12q12NCBI
HuRef1241,929,510 - 42,335,961 (-)NCBIHuRef
CHM1_11244,867,040 - 45,272,689 (-)NCBICHM1_1
T2T-CHM13v2.01244,466,949 - 44,872,599 (-)NCBIT2T-CHM13v2.0
Nell2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391595,117,321 - 95,426,677 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1594,973,111 - 95,426,440 (-)EnsemblGRCm39 Ensembl
GRCm381595,219,440 - 95,528,796 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1595,075,230 - 95,528,559 (-)EnsemblGRCm38mm10GRCm38
MGSCv371595,049,881 - 95,359,137 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361595,048,113 - 95,356,432 (-)NCBIMGSCv36mm8
Celera1597,364,534 - 97,674,925 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1549.39NCBI
Nell2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87128,222,333 - 128,542,127 (-)NCBIGRCr8
mRatBN7.27126,343,089 - 126,662,903 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7126,198,851 - 126,733,503 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7128,140,978 - 128,460,541 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07130,366,500 - 130,686,074 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07130,268,233 - 130,594,773 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07136,526,497 - 136,853,820 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7136,526,496 - 136,853,957 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07136,173,239 - 136,494,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47133,758,271 - 134,080,104 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17133,835,295 - 134,156,541 (-)NCBI
Celera7122,721,504 - 123,171,087 (-)NCBICelera
Cytogenetic Map7q35NCBI
Nell2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555003,669,837 - 4,080,443 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555003,669,893 - 4,049,765 (-)NCBIChiLan1.0ChiLan1.0
NELL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21049,258,879 - 49,665,010 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11249,255,637 - 49,661,768 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01243,820,215 - 44,226,249 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11244,680,223 - 45,094,070 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1244,688,209 - 45,094,070 (+)Ensemblpanpan1.1panPan2
NELL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1279,300,001 - 9,680,974 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl279,299,893 - 9,680,363 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2736,632,740 - 37,013,748 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,488,781 - 9,870,311 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,551,037 - 9,870,309 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1279,358,260 - 9,676,754 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,396,929 - 9,716,175 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02736,867,127 - 37,248,415 (-)NCBIUU_Cfam_GSD_1.0
Nell2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494569,939,345 - 70,302,004 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365122,863,485 - 3,224,941 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365122,862,823 - 3,225,350 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NELL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl575,505,099 - 75,893,454 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1575,505,092 - 75,837,324 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2578,515,865 - 78,687,458 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NELL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11140,701,718 - 41,057,489 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1140,701,723 - 41,057,349 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037205,411,968 - 205,768,291 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004863157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004863158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004863159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01078842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01078867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH168073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000011133   ⟹   ENSHGLP00000011010
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248167,503,067 - 8,007,081 (+)Ensembl
RefSeq Acc Id: XM_004863157   ⟹   XP_004863214
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248167,502,615 - 8,005,589 (+)NCBI
RefSeq Acc Id: XM_004863158   ⟹   XP_004863215
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248167,503,251 - 8,005,589 (+)NCBI
RefSeq Acc Id: XM_004863159   ⟹   XP_004863216
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248167,503,098 - 8,006,241 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004863214 (Get FASTA)   NCBI Sequence Viewer  
  XP_004863215 (Get FASTA)   NCBI Sequence Viewer  
  XP_004863216 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB03414 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011010
Reference Protein Sequences
RefSeq Acc Id: XP_004863214   ⟸   XM_004863157
- Peptide Label: isoform X1
- UniProtKB: G5B2A3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863216   ⟸   XM_004863159
- Peptide Label: isoform X1
- UniProtKB: G5B2A3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863215   ⟸   XM_004863158
- Peptide Label: isoform X2
- UniProtKB: G5B2A3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000011010   ⟸   ENSHGLT00000011133


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007898 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011133 ENTREZGENE
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  6.20.200.20 UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  EGF_dom UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  TSPN-like_N UniProtKB/TrEMBL
  VWF_dom UniProtKB/TrEMBL
NCBI Gene Nell2 ENTREZGENE
PANTHER NEL HOMOLOG UniProtKB/TrEMBL
  PROTEIN KINASE C-BINDING PROTEIN NELL2 UniProtKB/TrEMBL
Pfam EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  VWFC_1 UniProtKB/TrEMBL
  VWFC_2 UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  TSPN UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
  VWC_out UniProtKB/TrEMBL
Superfamily-SCOP Concanavalin A-like lectins/glucanases UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
  FnI-like domain UniProtKB/TrEMBL
  Growth factor receptor domain UniProtKB/TrEMBL
UniProt G5B2A3 ENTREZGENE, UniProtKB/TrEMBL