Cand2 (cullin associated and neddylation dissociated 2 (putative)) - Rat Genome Database

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Gene: Cand2 (cullin associated and neddylation dissociated 2 (putative)) Heterocephalus glaber
Analyze
Symbol: Cand2
Name: cullin associated and neddylation dissociated 2 (putative)
RGD ID: 18924188
Description: ENCODES a protein that exhibits TBP-class protein binding (ortholog); INVOLVED IN protein ubiquitination (inferred); SCF complex assembly (inferred); ASSOCIATED WITH Familial Cerebral Cavernous Malformation (ortholog); genetic disease (ortholog); Postoperative Atrial Fibrillation (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cullin-associated NEDD8-dissociated protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624872404,495 - 429,322 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624872404,263 - 429,866 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Cand2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624872404,495 - 429,322 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624872404,263 - 429,866 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CAND2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38312,796,680 - 12,834,803 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl312,796,472 - 12,834,804 (+)EnsemblGRCh38hg38GRCh38
GRCh37312,838,179 - 12,876,302 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36312,813,171 - 12,851,301 (+)NCBINCBI36Build 36hg18NCBI36
Celera312,776,461 - 12,814,604 (+)NCBICelera
Cytogenetic Map3p25.2NCBI
HuRef312,772,260 - 12,810,226 (+)NCBIHuRef
CHM1_1312,788,141 - 12,826,306 (+)NCBICHM1_1
T2T-CHM13v2.0312,798,170 - 12,836,312 (+)NCBIT2T-CHM13v2.0
Cand2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396115,751,518 - 115,782,516 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6115,751,499 - 115,782,518 (+)EnsemblGRCm39 Ensembl
GRCm386115,774,557 - 115,805,555 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6115,774,538 - 115,805,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv376115,724,575 - 115,755,573 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366115,740,194 - 115,770,488 (+)NCBIMGSCv36mm8
Celera6117,614,220 - 117,645,199 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.71NCBI
Cand2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84150,507,659 - 150,535,755 (+)NCBIGRCr8
mRatBN7.24148,835,050 - 148,864,039 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4148,835,053 - 148,863,153 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4155,063,763 - 155,091,880 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04150,847,780 - 150,875,897 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04149,470,682 - 149,498,799 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04147,686,487 - 147,714,593 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4147,686,490 - 147,714,585 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04210,970,266 - 210,998,152 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44151,912,174 - 151,940,734 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14152,157,014 - 152,185,575 (+)NCBI
Celera4137,725,100 - 137,753,194 (+)NCBICelera
Cytogenetic Map4q42NCBI
Cand2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542917,891,796 - 17,913,866 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542917,891,306 - 17,913,961 (-)NCBIChiLan1.0ChiLan1.0
CAND2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2212,781,415 - 12,817,289 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1312,786,216 - 12,822,052 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0312,722,259 - 12,757,983 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1313,066,133 - 13,102,246 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl313,066,135 - 13,102,246 (+)Ensemblpanpan1.1panPan2
CAND2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1205,756,576 - 5,789,892 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl205,757,566 - 5,811,408 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha205,793,865 - 5,827,176 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0205,786,186 - 5,819,576 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl205,787,164 - 5,820,601 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1205,502,290 - 5,535,612 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0205,855,197 - 5,888,510 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0205,830,851 - 5,864,169 (-)NCBIUU_Cfam_GSD_1.0
Cand2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494217,900,816 - 17,922,373 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936602988,312 - 1,008,781 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936602987,292 - 1,008,825 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAND2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1368,758,734 - 68,787,192 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11368,758,739 - 68,787,200 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21376,028,327 - 76,057,637 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAND2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12248,771,419 - 48,809,911 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2248,771,987 - 48,809,093 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041117,679,110 - 117,717,259 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000022026   ⟹   ENSHGLP00000021816
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624872404,495 - 429,322 (+)Ensembl
RefSeq Acc Id: XM_004870446   ⟹   XP_004870503
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872404,263 - 429,866 (+)NCBI
RefSeq Acc Id: XM_021248816   ⟹   XP_021104475
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872404,263 - 429,085 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004870503 (Get FASTA)   NCBI Sequence Viewer  
  XP_021104475 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021816
Reference Protein Sequences
RefSeq Acc Id: XP_004870503   ⟸   XM_004870446
- Peptide Label: isoform X1
- UniProtKB: G5BYD7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021104475   ⟸   XM_021248816
- Peptide Label: isoform X2
- UniProtKB: G5BYD7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000021816   ⟸   ENSHGLT00000022026


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015580 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022026 ENTREZGENE
Gene3D-CATH Leucine-rich Repeat Variant UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  CAND1/CAND2 UniProtKB/TrEMBL
  TATA-bd_TIP120 UniProtKB/TrEMBL
NCBI Gene Cand2 ENTREZGENE
PANTHER CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 2 UniProtKB/TrEMBL
  TIP120 UniProtKB/TrEMBL
Pfam TIP120 UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
UniProt G5BYD7 ENTREZGENE, UniProtKB/TrEMBL