Atf6b (activating transcription factor 6 beta) - Rat Genome Database

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Gene: Atf6b (activating transcription factor 6 beta) Heterocephalus glaber
Analyze
Symbol: Atf6b
Name: activating transcription factor 6 beta
RGD ID: 18924102
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN negative regulation of ATF6-mediated unfolded protein response (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); response to endoplasmic reticulum stress (ortholog); ASSOCIATED WITH genetic disease (ortholog); proteasome-associated autoinflammatory syndrome 1 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); protein-DNA complex (ortholog); RNA polymerase II transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Cyclic AMP-dependent transcription factor ATF-6 beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,184,261 - 24,194,904 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,185,203 - 24,194,351 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Atf6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,184,261 - 24,194,904 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,185,203 - 24,194,351 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ATF6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,115,264 - 32,128,246 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,115,264 - 32,128,253 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,083,041 - 32,096,023 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,191,016 - 32,203,995 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,191,024 - 32,203,995NCBI
Celera633,650,086 - 33,663,069 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef631,837,168 - 31,850,138 (-)NCBIHuRef
CHM1_1632,085,255 - 32,098,227 (-)NCBICHM1_1
T2T-CHM13v2.0631,968,456 - 31,981,438 (-)NCBIT2T-CHM13v2.0
Atf6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,866,120 - 34,874,048 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,866,120 - 34,874,048 (+)EnsemblGRCm39 Ensembl
GRCm381734,647,146 - 34,655,074 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,647,146 - 34,655,074 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,784,125 - 34,792,017 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,255,202 - 34,263,128 (+)NCBIMGSCv36mm8
Celera1737,742,351 - 37,750,243 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.22NCBI
Atf6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,095,534 - 4,103,534 (-)NCBIGRCr8
mRatBN7.2204,090,921 - 4,098,920 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,090,921 - 4,098,894 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,791,227 - 4,799,089 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,152,979 - 4,160,842 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,690,037 - 4,697,890 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,414,283 - 4,422,283 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,414,276 - 4,422,283 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,493,639 - 6,501,639 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,192,185 - 4,200,036 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,192,411 - 4,200,335 (-)NCBI
Celera203,931,428 - 3,939,279 (+)NCBICelera
Cytogenetic Map20p12NCBI
Atf6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437582,431 - 591,810 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437582,083 - 592,026 (-)NCBIChiLan1.0ChiLan1.0
ATF6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,577,837 - 46,590,853 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,539,307 - 42,552,297 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,762,161 - 31,775,136 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,643,124 - 32,655,617 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,643,124 - 32,655,617 (-)Ensemblpanpan1.1panPan2
ATF6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,515,186 - 1,525,165 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,515,503 - 1,525,110 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,649,820 - 1,659,539 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,648,775 - 1,664,022 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,654,226 - 1,663,944 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,517,328 - 1,527,049 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,582,585 - 1,592,516 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,649,158 - 1,658,950 (-)NCBIUU_Cfam_GSD_1.0
Atf6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494636,073,980 - 36,085,314 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,475,863 - 1,491,172 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,476,061 - 1,487,353 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATF6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,161,061 - 24,171,709 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,153,551 - 24,171,743 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,974,356 - 27,992,535 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATF6B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,901,226 - 39,913,702 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1739,901,226 - 39,914,142 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604432,017,693 - 32,030,453 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000023624   ⟹   ENSHGLP00000023407
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475424,184,261 - 24,194,904 (+)Ensembl
RefSeq Acc Id: XM_004846904   ⟹   XP_004846961
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475424,185,204 - 24,194,351 (+)NCBI
RefSeq Acc Id: XM_004846905   ⟹   XP_004846962
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475424,185,204 - 24,193,991 (+)NCBI
RefSeq Acc Id: XM_021260070   ⟹   XP_021115729
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475424,185,205 - 24,193,991 (+)NCBI
RefSeq Acc Id: XM_021260071   ⟹   XP_021115730
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475424,185,215 - 24,193,991 (+)NCBI
RefSeq Acc Id: XR_002395754
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475424,185,203 - 24,193,868 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846961 (Get FASTA)   NCBI Sequence Viewer  
  XP_004846962 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115729 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115730 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16089 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023407
  ENSHGLP00100025301
GenBank Protein JAN98416 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004846961   ⟸   XM_004846904
- Peptide Label: isoform X1
- UniProtKB: G5C3H8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004846962   ⟸   XM_004846905
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J2L2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021115729   ⟸   XM_021260070
- Peptide Label: isoform X3
- UniProtKB: G5C3H8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021115730   ⟸   XM_021260071
- Peptide Label: isoform X4
- UniProtKB: A0A0P6J2L2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000023407   ⟸   ENSHGLT00000023624


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016687 Ensembl, ENTREZGENE
  ENSHGLG00100018563 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000023624 ENTREZGENE
  ENSHGLT00100025559 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  bZIP_sf UniProtKB/TrEMBL
NCBI Gene Atf6b ENTREZGENE
PANTHER ATF6, ISOFORM C UniProtKB/TrEMBL
  PTHR46164:SF2 UniProtKB/TrEMBL
Pfam bZIP_1 UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP SSF57959 UniProtKB/TrEMBL
UniProt A0A0P6J2L2 ENTREZGENE, UniProtKB/TrEMBL
  G5C3H8 ENTREZGENE, UniProtKB/TrEMBL