Clpp (caseinolytic mitochondrial matrix peptidase proteolytic subunit) - Rat Genome Database

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Gene: Clpp (caseinolytic mitochondrial matrix peptidase proteolytic subunit) Heterocephalus glaber
Analyze
Symbol: Clpp
Name: caseinolytic mitochondrial matrix peptidase proteolytic subunit
RGD ID: 18923880
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); identical protein binding (ortholog); INVOLVED IN membrane protein proteolysis (ortholog); proteolysis involved in protein catabolic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); mucolipidosis type IV (ortholog); Perrault syndrome (ortholog); FOUND IN endopeptidase Clp complex (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent Clp protease proteolytic subunit, mitochondrial; ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog; Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248283,498,794 - 3,505,769 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248283,499,141 - 3,505,774 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Clpp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248283,498,794 - 3,505,769 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248283,499,141 - 3,505,774 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CLPP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38196,361,531 - 6,370,242 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl196,361,531 - 6,370,242 (+)EnsemblGRCh38hg38GRCh38
GRCh37196,361,542 - 6,370,253 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36196,312,463 - 6,319,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 34196,312,462 - 6,319,915NCBI
Celera196,300,249 - 6,307,702 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef196,121,624 - 6,129,060 (+)NCBIHuRef
CHM1_1196,361,087 - 6,368,540 (+)NCBICHM1_1
T2T-CHM13v2.0196,350,432 - 6,359,144 (+)NCBIT2T-CHM13v2.0
Clpp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391757,297,264 - 57,303,371 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1757,297,305 - 57,303,188 (+)EnsemblGRCm39 Ensembl
GRCm381756,990,264 - 56,996,371 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,990,305 - 56,996,188 (+)EnsemblGRCm38mm10GRCm38
MGSCv371757,129,687 - 57,135,794 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361756,675,433 - 56,681,311 (+)NCBIMGSCv36mm8
Celera1761,338,190 - 61,344,297 (+)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.61NCBI
Clpp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,917,305 - 1,924,706 (+)NCBIGRCr8
mRatBN7.291,831,680 - 1,837,700 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,830,311 - 1,837,693 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx92,265,916 - 2,271,581 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.097,615,274 - 7,620,940 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.096,571,135 - 6,576,801 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0910,048,715 - 10,056,068 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,048,886 - 10,054,359 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,049,365 - 9,055,397 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,679,585 - 6,686,938 (-)NCBICelera
Cytogenetic Map9q11NCBI
Clpp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554953,223,709 - 3,233,562 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554953,224,968 - 3,233,482 (-)NCBIChiLan1.0ChiLan1.0
CLPP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22010,762,202 - 10,769,604 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,988,131 - 9,995,526 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0195,382,323 - 5,389,788 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1196,304,462 - 6,312,077 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl196,304,462 - 6,312,077 (+)Ensemblpanpan1.1panPan2
CLPP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12053,788,114 - 53,794,217 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2053,788,164 - 53,794,174 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2053,535,022 - 53,541,124 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02054,442,379 - 54,448,486 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2054,440,903 - 54,448,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12053,508,841 - 53,514,945 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02053,957,180 - 53,963,271 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02054,186,933 - 54,193,048 (-)NCBIUU_Cfam_GSD_1.0
Clpp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118214,106,746 - 214,111,595 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365883,722,941 - 3,731,439 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365883,723,188 - 3,728,037 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLPP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl272,707,158 - 72,713,475 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1272,707,363 - 72,713,481 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2273,220,872 - 73,226,365 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CLPP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.165,977,339 - 5,984,926 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl65,977,450 - 5,986,919 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660812,038,458 - 2,046,910 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000015110   ⟹   ENSHGLP00000014960
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248283,498,794 - 3,505,769 (+)Ensembl
RefSeq Acc Id: XM_004865615   ⟹   XP_004865672
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248283,499,141 - 3,505,774 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004865672 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16420 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014960
  ENSHGLP00100000931
Reference Protein Sequences
RefSeq Acc Id: XP_004865672   ⟸   XM_004865615
- UniProtKB: G5C4F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014960   ⟸   ENSHGLT00000015110


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010702 Ensembl, ENTREZGENE
  ENSHGLG00100000755 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000015110 ENTREZGENE
  ENSHGLT00100000963 UniProtKB/TrEMBL
InterPro ClpP UniProtKB/TrEMBL
  ClpP/crotonase-like_dom_sf UniProtKB/TrEMBL
  ClpP/TepA UniProtKB/TrEMBL
  ClpP_His_AS UniProtKB/TrEMBL
  ClpP_Ser_AS UniProtKB/TrEMBL
KEGG Report hgl:101720532 UniProtKB/TrEMBL
NCBI Gene Clpp ENTREZGENE
PANTHER ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR10381 UniProtKB/TrEMBL
Pfam CLP_protease UniProtKB/TrEMBL
PRINTS CLPPROTEASEP UniProtKB/TrEMBL
PROSITE CLP_PROTEASE_HIS UniProtKB/TrEMBL
  CLP_PROTEASE_SER UniProtKB/TrEMBL
Superfamily-SCOP SSF52096 UniProtKB/TrEMBL
UniProt G5C4F9 ENTREZGENE, UniProtKB/TrEMBL