Osbpl6 (oxysterol binding protein like 6) - Rat Genome Database

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Gene: Osbpl6 (oxysterol binding protein like 6) Heterocephalus glaber
Analyze
Symbol: Osbpl6
Name: oxysterol binding protein like 6
RGD ID: 18923253
Description: ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); obsolete sterol transporter activity (inferred); INVOLVED IN regulation of cholesterol transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN early endosome membrane (ortholog); endoplasmic reticulum membrane (ortholog); nuclear membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Oxysterol-binding protein-related protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Osbpl6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
OSBPL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382178,193,774 - 178,402,893 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2178,194,481 - 178,402,893 (+)EnsemblGRCh38hg38GRCh38
GRCh372179,059,239 - 179,267,620 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362178,767,620 - 178,969,123 (+)NCBINCBI36Build 36hg18NCBI36
Build 342179,010,477 - 179,086,380NCBI
Celera2172,662,267 - 172,863,763 (+)NCBICelera
Cytogenetic Map2q31.2NCBI
HuRef2170,930,068 - 171,134,835 (+)NCBIHuRef
CHM1_12179,065,294 - 179,270,178 (+)NCBICHM1_1
T2T-CHM13v2.02178,676,512 - 178,885,713 (+)NCBIT2T-CHM13v2.0
Osbpl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39276,236,848 - 76,430,991 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl276,236,852 - 76,430,991 (+)EnsemblGRCm39 Ensembl
GRCm38276,406,504 - 76,600,647 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl276,406,508 - 76,600,647 (+)EnsemblGRCm38mm10GRCm38
MGSCv37276,244,595 - 76,438,704 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36276,207,377 - 76,401,486 (+)NCBIMGSCv36mm8
Celera278,072,919 - 78,262,320 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.94NCBI
Osbpl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8381,751,020 - 81,948,186 (+)NCBIGRCr8
mRatBN7.2361,343,776 - 61,541,170 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl361,343,809 - 61,537,102 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx364,792,795 - 64,891,290 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0373,376,452 - 73,474,945 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0371,144,020 - 71,242,469 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0363,257,646 - 63,455,105 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl363,353,178 - 63,454,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0369,831,007 - 70,028,482 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4359,190,488 - 59,288,770 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1359,079,786 - 59,185,092 (+)NCBI
Celera360,925,035 - 61,023,211 (+)NCBICelera
Cytogenetic Map3q24NCBI
Osbpl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540318,448,537 - 18,572,721 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540318,441,548 - 18,575,838 (-)NCBIChiLan1.0ChiLan1.0
OSBPL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21380,838,769 - 81,041,485 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B80,853,720 - 81,060,096 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B65,449,726 - 65,656,040 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B183,155,488 - 183,361,686 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B183,247,028 - 183,361,686 (+)Ensemblpanpan1.1panPan2
OSBPL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13621,872,934 - 22,024,877 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3621,908,947 - 22,021,426 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3621,892,449 - 22,043,257 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03622,016,989 - 22,168,309 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3622,051,679 - 22,164,707 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13622,126,718 - 22,277,949 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03622,089,669 - 22,240,525 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03622,205,208 - 22,356,553 (+)NCBIUU_Cfam_GSD_1.0
Osbpl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303138,861,008 - 139,056,536 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365097,414,769 - 7,613,622 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365097,414,887 - 7,610,412 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSBPL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1583,872,742 - 84,101,299 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11583,872,747 - 84,101,302 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21593,542,518 - 93,635,049 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OSBPL6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11063,744,984 - 63,954,469 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1063,860,341 - 63,950,870 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040135,620,068 - 135,826,088 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004868136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013066838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013066839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01088089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01088090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01088091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01088092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01088093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01088094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01088095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01004918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH167841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_004868136   ⟹   XP_004868193
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_013066838   ⟹   XP_012922292
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_013066839   ⟹   XP_012922293
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844314,431 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247119   ⟹   XP_021102778
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247120   ⟹   XP_021102779
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247121   ⟹   XP_021102780
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247122   ⟹   XP_021102781
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247123   ⟹   XP_021102782
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247124   ⟹   XP_021102783
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247125   ⟹   XP_021102784
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247126   ⟹   XP_021102785
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 380,699 (+)NCBI
RefSeq Acc Id: XM_021247127   ⟹   XP_021102786
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 353,019 (+)NCBI
RefSeq Acc Id: XM_021247128   ⟹   XP_021102787
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624844174,068 - 343,996 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021102778   ⟸   XM_021247119
- Peptide Label: isoform X1
- UniProtKB: G5B0U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922292   ⟸   XM_013066838
- Peptide Label: isoform X1
- UniProtKB: G5B0U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102781   ⟸   XM_021247122
- Peptide Label: isoform X5
- UniProtKB: G5B0U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102779   ⟸   XM_021247120
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J594 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102785   ⟸   XM_021247126
- Peptide Label: isoform X9
- UniProtKB: A0A0P6J594 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102780   ⟸   XM_021247121
- Peptide Label: isoform X4
- UniProtKB: A0A0P6J594 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102783   ⟸   XM_021247124
- Peptide Label: isoform X7
- UniProtKB: A0A0P6J594 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102782   ⟸   XM_021247123
- Peptide Label: isoform X6
- UniProtKB: G5B0U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102784   ⟸   XM_021247125
- Peptide Label: isoform X8
- UniProtKB: G5B0U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868193   ⟸   XM_004868136
- Peptide Label: isoform X1
- UniProtKB: G5B0U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102786   ⟸   XM_021247127
- Peptide Label: isoform X10
RefSeq Acc Id: XP_021102787   ⟸   XM_021247128
- Peptide Label: isoform X11
RefSeq Acc Id: XP_012922293   ⟸   XM_013066839
- Peptide Label: isoform X2
- UniProtKB: G5B0U6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003065 ENTREZGENE
Ensembl Transcript ENSHGLT00000004232 ENTREZGENE
  ENSHGLT00000004233 ENTREZGENE
  ENSHGLT00000004234 ENTREZGENE
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.40.160.120 UniProtKB/TrEMBL
  3.30.70.3490 UniProtKB/TrEMBL
InterPro OSBP_sf UniProtKB/TrEMBL
  Oxysterol-bd UniProtKB/TrEMBL
  Oxysterol-bd_CS UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_8 UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Osbpl6 ENTREZGENE
PANTHER OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 6 UniProtKB/TrEMBL
  PTHR10972 UniProtKB/TrEMBL
Pfam Oxysterol_BP UniProtKB/TrEMBL
  PH_8 UniProtKB/TrEMBL
PROSITE OSBP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF144000 UniProtKB/TrEMBL
UniProt A0A0P6J594 ENTREZGENE, UniProtKB/TrEMBL
  G5B0U6 ENTREZGENE, UniProtKB/TrEMBL