Pla2g4d (phospholipase A2 group IVD) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Pla2g4d (phospholipase A2 group IVD) Heterocephalus glaber
Analyze
Symbol: Pla2g4d
Name: phospholipase A2 group IVD
RGD ID: 18922984
Description: ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent phospholipase A2 activity (inferred); calcium-dependent phospholipid binding (inferred); INVOLVED IN glycerophospholipid catabolic process (inferred); lipid catabolic process (inferred); lipid metabolic process (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytosolic phospholipase A2 delta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248049,238,057 - 9,256,503 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pla2g4d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248049,238,057 - 9,256,503 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PLA2G4D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381542,067,009 - 42,094,562 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1542,067,009 - 42,094,562 (-)EnsemblGRCh38hg38GRCh38
GRCh371542,359,207 - 42,386,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361540,147,173 - 40,174,044 (-)NCBINCBI36Build 36hg18NCBI36
Build 341540,146,498 - 40,151,368NCBI
Celera1519,127,581 - 19,154,452 (-)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1519,207,893 - 19,235,242 (-)NCBIHuRef
CHM1_11542,478,319 - 42,505,190 (-)NCBICHM1_1
T2T-CHM13v2.01539,873,000 - 39,900,554 (-)NCBIT2T-CHM13v2.0
Pla2g4d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,096,347 - 120,119,678 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,096,076 - 120,119,678 (-)EnsemblGRCm39 Ensembl
GRCm382120,265,866 - 120,289,069 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2120,265,595 - 120,289,197 (-)EnsemblGRCm38mm10GRCm38
MGSCv372120,091,605 - 120,114,805 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362119,957,310 - 119,980,510 (-)NCBIMGSCv36mm8
Celera2121,420,286 - 121,443,397 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.31NCBI
Pla2g4d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,674,743 - 127,695,991 (-)NCBIGRCr8
mRatBN7.23107,220,973 - 107,242,224 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,220,978 - 107,242,224 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03112,040,827 - 112,061,847 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,041,533 - 112,061,796 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,589,300 - 118,609,563 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43106,758,373 - 106,778,915 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3106,129,471 - 106,150,773 (-)NCBICelera
Cytogenetic Map3q35NCBI
Pla2g4d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554168,841,954 - 8,860,353 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554168,841,645 - 8,860,381 (-)NCBIChiLan1.0ChiLan1.0
PLA2G4D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21631,311,381 - 31,331,038 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11535,462,638 - 35,482,296 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01521,021,875 - 21,048,848 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11539,182,100 - 39,208,996 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1539,182,100 - 39,208,996 (-)Ensemblpanpan1.1panPan2
PLA2G4D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1309,091,147 - 9,115,090 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl309,092,001 - 9,115,363 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha309,147,400 - 9,173,232 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0309,224,119 - 9,249,959 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl309,226,331 - 9,250,007 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1309,144,510 - 9,170,332 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0309,248,779 - 9,274,621 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0309,383,819 - 9,409,657 (-)NCBIUU_Cfam_GSD_1.0
Pla2g4d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,537,755 - 87,561,169 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364715,386,762 - 5,409,174 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364715,386,762 - 5,409,165 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA2G4D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1129,247,159 - 129,271,028 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11129,251,495 - 129,270,952 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21144,183,508 - 144,207,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLA2G4D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12640,895,718 - 40,923,092 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2640,897,660 - 40,922,031 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048100,080,579 - 100,105,910 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_021241900   ⟹   XP_021097559
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248049,238,057 - 9,256,503 (-)NCBI
RefSeq Acc Id: XM_021241901   ⟹   XP_021097560
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248049,238,057 - 9,256,503 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021097559 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097560 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021097560   ⟸   XM_021241901
- Peptide Label: isoform X2
- UniProtKB: G5BM23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097559   ⟸   XM_021241900
- Peptide Label: isoform X1
- UniProtKB: G5BM23 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Gene3D-CATH C2 domain UniProtKB/TrEMBL
  Cytosolic phospholipase A2 catalytic domain UniProtKB/TrEMBL
InterPro Acyl_Trfase/lysoPLipase UniProtKB/TrEMBL
  C2_cPLA2 UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  cPLA2_C2 UniProtKB/TrEMBL
  LysoPLipase_cat_dom UniProtKB/TrEMBL
NCBI Gene Pla2g4d ENTREZGENE
PANTHER CYTOSOLIC PHOSPHOLIPASE A2 UniProtKB/TrEMBL
  CYTOSOLIC PHOSPHOLIPASE A2 DELTA UniProtKB/TrEMBL
Pfam cPLA2_C2 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PLA2_B UniProtKB/TrEMBL
PROSITE PLA2C UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART PLAc UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP C2 domain (Calcium/lipid-binding domain, CaLB) UniProtKB/TrEMBL
  FabD/lysophospholipase-like UniProtKB/TrEMBL
UniProt G5BM23 ENTREZGENE, UniProtKB/TrEMBL