Pla1a (phospholipase A1 member A) - Rat Genome Database

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Gene: Pla1a (phospholipase A1 member A) Heterocephalus glaber
Analyze
Symbol: Pla1a
Name: phospholipase A1 member A
RGD ID: 18922509
Description: ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); lipase activity (inferred); lipoprotein lipase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); lipid metabolic process (inferred); triglyceride catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN acrosomal membrane (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473128,511,156 - 28,578,646 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473128,513,863 - 28,587,394 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pla1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473128,511,156 - 28,578,646 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473128,513,863 - 28,587,394 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PLA1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383119,597,885 - 119,629,811 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3119,597,875 - 119,629,811 (+)EnsemblGRCh38hg38GRCh38
GRCh373119,316,732 - 119,348,658 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,799,436 - 120,831,342 (+)NCBINCBI36Build 36hg18NCBI36
Build 343120,799,434 - 120,831,341NCBI
Celera3117,725,283 - 117,757,207 (+)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3116,692,381 - 116,724,322 (+)NCBIHuRef
CHM1_13119,280,198 - 119,312,157 (+)NCBICHM1_1
T2T-CHM13v2.03122,317,610 - 122,349,514 (+)NCBIT2T-CHM13v2.0
Pla1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,214,245 - 38,253,553 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1638,216,479 - 38,253,507 (-)EnsemblGRCm39 Ensembl
GRCm381638,396,117 - 38,433,191 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,396,117 - 38,433,145 (-)EnsemblGRCm38mm10GRCm38
MGSCv371638,396,203 - 38,433,225 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361638,315,356 - 38,352,378 (-)NCBIMGSCv36mm8
Celera1638,806,434 - 38,843,606 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.83NCBI
Pla1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81175,825,626 - 75,863,296 (+)NCBIGRCr8
mRatBN7.21162,320,112 - 62,357,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1162,320,493 - 62,357,779 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1171,132,637 - 71,170,302 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01163,794,884 - 63,832,553 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,845,532 - 62,883,163 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,882,024 - 64,919,714 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,882,288 - 64,919,579 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01167,166,387 - 67,203,665 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41164,099,837 - 64,137,353 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11164,157,425 - 64,194,945 (+)NCBI
Celera1161,822,091 - 61,859,256 (+)NCBICelera
Cytogenetic Map11q21NCBI
Pla1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542719,297,938 - 19,335,825 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542719,298,004 - 19,334,454 (+)NCBIChiLan1.0ChiLan1.0
PLA1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22117,575,584 - 117,606,829 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13117,580,362 - 117,612,292 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03116,720,777 - 116,752,030 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13123,633,173 - 123,664,383 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3123,633,173 - 123,664,383 (+)Ensemblpanpan1.1panPan2
PLA1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13323,222,217 - 23,262,603 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3323,236,161 - 23,288,651 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3323,252,379 - 23,292,764 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03323,460,284 - 23,500,933 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3323,474,593 - 23,500,910 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13323,262,901 - 23,303,070 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03323,298,489 - 23,338,887 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03323,867,996 - 23,908,366 (+)NCBIUU_Cfam_GSD_1.0
Pla1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602130,973,457 - 131,006,822 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365366,515,115 - 6,548,954 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365366,515,151 - 6,548,943 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13140,638,521 - 140,665,961 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113140,638,522 - 140,666,064 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213149,969,013 - 149,999,194 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLA1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12261,190,815 - 61,222,540 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2261,190,721 - 61,222,182 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041105,091,764 - 105,122,399 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017542   ⟹   ENSHGLP00000017369
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473128,511,156 - 28,578,646 (-)Ensembl
RefSeq Acc Id: XM_021263122   ⟹   XP_021118781
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473128,540,399 - 28,578,529 (-)NCBI
RefSeq Acc Id: XM_021263125   ⟹   XP_021118784
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473128,513,863 - 28,578,529 (-)NCBI
RefSeq Acc Id: XM_021263128   ⟹   XP_021118787
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473128,540,399 - 28,578,529 (-)NCBI
RefSeq Acc Id: XM_021263131   ⟹   XP_021118790
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473128,541,361 - 28,578,529 (-)NCBI
RefSeq Acc Id: XM_021263132   ⟹   XP_021118791
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473128,540,399 - 28,587,394 (-)NCBI
RefSeq Acc Id: XM_021263136   ⟹   XP_021118795
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473128,540,399 - 28,587,394 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021118784   ⟸   XM_021263125
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021118795   ⟸   XM_021263136
- Peptide Label: isoform X5
RefSeq Acc Id: XP_021118791   ⟸   XM_021263132
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021118787   ⟸   XM_021263128
- Peptide Label: isoform X2
- UniProtKB: G5AUA1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118781   ⟸   XM_021263122
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021118790   ⟸   XM_021263131
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000017369   ⟸   ENSHGLT00000017542


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012437 Ensembl, ENTREZGENE
  ENSHGLG00100003082 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017542 ENTREZGENE
  ENSHGLT00100004105 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Lipase/vitellogenin UniProtKB/TrEMBL
  Lipase_LIPH UniProtKB/TrEMBL
  Lipase_N UniProtKB/TrEMBL
  TAG_lipase UniProtKB/TrEMBL
KEGG Report hgl:101703405 UniProtKB/TrEMBL
NCBI Gene Pla1a ENTREZGENE
PANTHER PHOSPHOLIPASE A1 MEMBER A UniProtKB/TrEMBL
  PTHR11610 UniProtKB/TrEMBL
Pfam Lipase UniProtKB/TrEMBL
PIRSF Lipoprotein_lipase_LIPH UniProtKB/TrEMBL
PRINTS TAGLIPASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt G5AUA1 ENTREZGENE, UniProtKB/TrEMBL