Rorb (RAR related orphan receptor B) - Rat Genome Database

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Gene: Rorb (RAR related orphan receptor B) Heterocephalus glaber
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Symbol: Rorb
Name: RAR related orphan receptor B
RGD ID: 18922247
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN amacrine cell differentiation (ortholog); cellular response to retinoic acid (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH Childhood Absence Epilepsy 1 (ortholog); endometriosis (ortholog); epilepsy (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Nuclear receptor ROR-beta; retinoid-related orphan receptor beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248112,076,437 - 2,277,040 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248112,076,474 - 2,281,933 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (IEA)

References
Additional References at PubMed
PMID:21452207   PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rorb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248112,076,437 - 2,277,040 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248112,076,474 - 2,281,933 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RORB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38974,497,335 - 74,693,177 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl974,497,335 - 74,693,177 (+)EnsemblGRCh38hg38GRCh38
GRCh37977,112,251 - 77,308,093 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36976,302,072 - 76,491,937 (+)NCBINCBI36Build 36hg18NCBI36
Build 34974,341,852 - 74,531,348NCBI
Celera947,686,322 - 47,876,161 (+)NCBICelera
Cytogenetic Map9q21.13NCBI
HuRef946,935,089 - 47,124,700 (+)NCBIHuRef
CHM1_1977,258,972 - 77,448,757 (+)NCBICHM1_1
T2T-CHM13v2.0986,650,612 - 86,846,447 (+)NCBIT2T-CHM13v2.0
Rorb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391918,907,966 - 19,088,560 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1918,907,969 - 19,088,560 (-)EnsemblGRCm39 Ensembl
GRCm381918,930,609 - 19,111,196 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1918,930,605 - 19,111,196 (-)EnsemblGRCm38mm10GRCm38
MGSCv371919,011,058 - 19,185,686 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361919,003,591 - 19,068,140 (-)NCBIMGSCv36mm8
Celera1919,627,465 - 19,802,185 (-)NCBICelera
Cytogenetic Map19BNCBI
cM Map1913.28NCBI
Rorb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81225,790,216 - 225,970,973 (-)NCBIGRCr8
mRatBN7.21216,363,629 - 216,544,390 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1216,363,629 - 216,544,390 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1224,690,925 - 224,871,663 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01231,627,471 - 231,808,206 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01224,445,448 - 224,626,180 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01234,252,757 - 234,442,597 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1234,252,757 - 234,435,839 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,354,340 - 241,541,103 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,545,682 - 222,726,307 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11222,709,413 - 222,890,308 (-)NCBI
Celera1213,658,839 - 213,838,721 (-)NCBICelera
Cytogenetic Map1q51NCBI
Rorb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555124,362,287 - 4,541,445 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555124,362,287 - 4,541,432 (-)NCBIChiLan1.0ChiLan1.0
RORB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21173,662,727 - 73,858,291 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1973,668,668 - 73,864,232 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0950,144,836 - 50,340,910 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1973,351,856 - 73,543,036 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl973,469,767 - 73,543,030 (+)Ensemblpanpan1.1panPan2
RORB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1183,470,569 - 83,666,200 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl183,476,816 - 83,666,061 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha183,929,462 - 84,129,651 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0183,916,495 - 84,116,525 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl183,921,419 - 84,116,545 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1183,667,160 - 83,867,996 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0183,385,976 - 83,586,352 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0184,146,713 - 84,347,046 (-)NCBIUU_Cfam_GSD_1.0
Rorb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947130,696,123 - 130,878,474 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650310,295,167 - 10,470,813 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650310,294,530 - 10,473,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RORB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1227,574,648 - 227,772,671 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11227,573,972 - 227,776,806 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,597,054 - 254,678,939 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RORB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11285,545,609 - 85,735,804 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1285,545,608 - 85,732,780 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603873,986,850 - 74,183,347 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000000877   ⟹   ENSHGLP00000000837
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248112,076,437 - 2,277,040 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000000878   ⟹   ENSHGLP00000000838
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248112,203,886 - 2,277,040 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000000879   ⟹   ENSHGLP00000000839
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248112,220,696 - 2,277,040 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000000880   ⟹   ENSHGLP00000000840
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248112,220,795 - 2,277,040 (+)Ensembl
RefSeq Acc Id: XM_004862519   ⟹   XP_004862576
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248112,076,474 - 2,281,933 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004862576 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAJ46222 (Get FASTA)   NCBI Sequence Viewer  
  EHB17403 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000000837
GenBank Protein JAO00352 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004862576   ⟸   XM_004862519
- UniProtKB: A0A0P6J9L7 (UniProtKB/TrEMBL),   G5C792 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000000838   ⟸   ENSHGLT00000000878
Ensembl Acc Id: ENSHGLP00000000837   ⟸   ENSHGLT00000000877
Ensembl Acc Id: ENSHGLP00000000840   ⟸   ENSHGLT00000000880
Ensembl Acc Id: ENSHGLP00000000839   ⟸   ENSHGLT00000000879


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000695 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000000877 ENTREZGENE
Gene3D-CATH 1.10.565.10 UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/TrEMBL
  NR_DBD_ROR UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/TrEMBL
  ROR_rcpt UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
KEGG Report hgl:101707549 UniProtKB/TrEMBL
NCBI Gene Rorb ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR HR3-RELATED UniProtKB/TrEMBL
  NUCLEAR RECEPTOR ROR-BETA UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/TrEMBL
  zf-C4 UniProtKB/TrEMBL
PRINTS RORNUCRECPTR UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/TrEMBL
SMART HOLI UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  SSF48508 UniProtKB/TrEMBL
UniProt A0A0P6J9L7 ENTREZGENE, UniProtKB/TrEMBL
  E5RUX8_HETGA UniProtKB/TrEMBL
  G5C792 ENTREZGENE, UniProtKB/TrEMBL