Tram1 (translocation associated membrane protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Tram1 (translocation associated membrane protein 1) Heterocephalus glaber
Analyze
Symbol: Tram1
Name: translocation associated membrane protein 1
RGD ID: 18920861
Description: INVOLVED IN cotranslational protein targeting to membrane (inferred); protein insertion into ER membrane (inferred); protein transport (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: translocating chain-associated membrane protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474420,619,043 - 20,653,438 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474420,618,963 - 20,653,285 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tram1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474420,619,043 - 20,653,438 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474420,618,963 - 20,653,285 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TRAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38870,573,218 - 70,608,416 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl870,573,218 - 70,608,416 (-)EnsemblGRCh38hg38GRCh38
GRCh37871,485,453 - 71,520,651 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36871,648,227 - 71,683,158 (-)NCBINCBI36Build 36hg18NCBI36
Build 34871,648,226 - 71,683,158NCBI
Celera867,483,078 - 67,518,322 (-)NCBICelera
Cytogenetic Map8q13.3NCBI
HuRef866,978,304 - 67,013,532 (-)NCBIHuRef
CHM1_1871,541,019 - 71,576,230 (-)NCBICHM1_1
T2T-CHM13v2.0871,003,150 - 71,038,323 (-)NCBIT2T-CHM13v2.0
Tram1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,634,917 - 13,660,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,634,922 - 13,660,134 (-)EnsemblGRCm39 Ensembl
GRCm38113,564,693 - 13,589,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,564,698 - 13,589,910 (-)EnsemblGRCm38mm10GRCm38
MGSCv37113,554,783 - 13,579,945 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,549,916 - 13,575,078 (-)NCBIMGSCv36mm8
Celera113,514,581 - 13,539,714 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.18NCBI
Tram1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8510,425,710 - 10,450,669 (+)NCBIGRCr8
mRatBN7.255,642,579 - 5,667,666 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl55,642,546 - 5,686,971 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx57,780,736 - 7,805,759 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.059,419,625 - 9,444,647 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.059,110,778 - 9,135,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.055,215,196 - 5,297,337 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl55,215,196 - 5,316,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0510,062,171 - 10,062,451 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0510,121,579 - 10,138,210 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.454,844,208 - 4,869,207 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.154,844,207 - 4,869,206 (+)NCBI
Celera55,235,381 - 5,252,006 (+)NCBICelera
Cytogenetic Map5q11NCBI
Tram1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554449,110,807 - 9,152,125 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554449,110,533 - 9,153,585 (+)NCBIChiLan1.0ChiLan1.0
TRAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2786,306,766 - 86,342,548 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1861,936,216 - 61,972,011 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0867,098,588 - 67,133,511 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1868,759,038 - 68,793,750 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl868,759,040 - 68,794,303 (-)Ensemblpanpan1.1panPan2
TRAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12919,669,622 - 19,703,707 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2919,669,628 - 19,703,669 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2919,929,189 - 19,963,216 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02919,766,644 - 19,800,987 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2919,766,644 - 19,800,983 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12919,804,740 - 19,838,512 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02919,871,008 - 19,905,124 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02920,151,950 - 20,186,017 (-)NCBIUU_Cfam_GSD_1.0
Tram1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530359,528,340 - 59,551,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649615,233,631 - 15,257,140 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649615,233,692 - 15,257,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl464,768,698 - 64,800,508 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1464,768,600 - 64,800,513 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2470,399,155 - 70,431,001 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRAM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1866,312,103 - 66,344,738 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl866,311,614 - 66,344,840 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603975,081,633 - 75,114,264 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000011610   ⟹   ENSHGLP00000011483
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474420,619,043 - 20,653,438 (+)Ensembl
RefSeq Acc Id: XM_004842062   ⟹   XP_004842119
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,618,963 - 20,653,285 (+)NCBI
RefSeq Acc Id: XM_021256028   ⟹   XP_021111687
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,618,963 - 20,653,285 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004842119 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111687 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011483
  ENSHGLP00100025098
GenBank Protein JAN98585 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004842119   ⟸   XM_004842062
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J4W7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111687   ⟸   XM_021256028
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J4W7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000011483   ⟸   ENSHGLT00000011610


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008235 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100018418 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000011610 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100025354 UniProtKB/TrEMBL
InterPro TLC-dom UniProtKB/TrEMBL
  Translocation_assoc_membrane UniProtKB/TrEMBL
NCBI Gene Tram1 ENTREZGENE
PANTHER PTHR12371 UniProtKB/TrEMBL
  TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1 UniProtKB/TrEMBL
Pfam TRAM_LAG1_CLN8 UniProtKB/TrEMBL
PIRSF Translocation_assoc_membrane UniProtKB/TrEMBL
PROSITE TLC UniProtKB/TrEMBL
SMART TLC UniProtKB/TrEMBL
UniProt A0A0P6J4W7 ENTREZGENE, UniProtKB/TrEMBL