Mocs2 (molybdenum cofactor synthesis 2) - Rat Genome Database

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Gene: Mocs2 (molybdenum cofactor synthesis 2) Heterocephalus glaber
Analyze
Symbol: Mocs2
Name: molybdenum cofactor synthesis 2
RGD ID: 18920677
Description: ENCODES a protein that exhibits identical protein binding (ortholog); molybdopterin synthase activity (ortholog); INVOLVED IN Mo-molybdopterin cofactor biosynthetic process (inferred); molybdopterin cofactor biosynthetic process (inferred); PARTICIPATES IN molybdenum cofactor biosynthetic pathway; ASSOCIATED WITH genetic disease (ortholog); molybdenum cofactor deficiency (ortholog); molybdenum cofactor deficiency type A (ortholog); FOUND IN molybdopterin synthase complex (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Molybdenum cofactor synthesis protein 2B; molybdopterin synthase catalytic subunit; molybdopterin synthase catalytic subunit small subunit MOCS2A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247596,261,933 - 6,271,509 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247596,261,970 - 6,272,246 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mocs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247596,261,933 - 6,271,509 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247596,261,970 - 6,272,246 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MOCS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38553,095,679 - 53,109,757 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl553,095,679 - 53,110,063 (-)EnsemblGRCh38hg38GRCh38
GRCh37552,391,509 - 52,405,587 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36552,429,649 - 52,441,355 (-)NCBINCBI36Build 36hg18NCBI36
Build 34552,429,653 - 52,441,355NCBI
Celera549,347,470 - 49,359,176 (-)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef549,363,558 - 49,377,653 (-)NCBIHuRef
CHM1_1552,394,058 - 52,408,152 (-)NCBICHM1_1
T2T-CHM13v2.0553,923,465 - 53,937,543 (-)NCBIT2T-CHM13v2.0
Mocs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913114,954,707 - 114,965,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13114,954,772 - 114,968,811 (+)EnsemblGRCm39 Ensembl
GRCm3813114,818,160 - 114,829,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13114,818,236 - 114,832,275 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713115,608,445 - 115,619,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613115,939,164 - 115,949,607 (+)NCBIMGSCv36mm8
Celera13119,161,937 - 119,173,119 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1364.61NCBI
Mocs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8248,237,655 - 48,249,394 (+)NCBIGRCr8
mRatBN7.2246,504,588 - 46,516,327 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl246,504,588 - 46,516,324 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx253,614,202 - 53,625,948 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0251,672,578 - 51,684,324 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0246,540,417 - 46,552,139 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0246,980,964 - 46,992,886 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl246,980,976 - 46,992,883 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0271,520,174 - 71,532,084 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4246,948,321 - 46,960,060 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1246,876,587 - 46,888,290 (+)NCBI
Celera242,260,839 - 42,272,490 (+)NCBICelera
Cytogenetic Map2q14NCBI
Mocs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544614,295,737 - 14,307,838 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544614,295,737 - 14,305,735 (+)NCBIChiLan1.0ChiLan1.0
MOCS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2460,831,376 - 60,843,005 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1558,984,997 - 58,996,220 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0560,920,268 - 60,931,990 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1562,539,208 - 62,550,926 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl562,539,214 - 62,550,921 (+)Ensemblpanpan1.1panPan2
MOCS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1462,153,828 - 62,164,154 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl462,153,296 - 62,185,492 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha461,928,792 - 61,939,117 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0462,651,866 - 62,662,174 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1462,427,116 - 62,437,429 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0462,551,658 - 62,561,990 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0463,078,354 - 63,088,687 (+)NCBIUU_Cfam_GSD_1.0
Mocs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213205,369,033 - 205,380,226 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648014,302,824 - 14,313,265 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOCS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1632,436,205 - 32,462,521 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11632,427,783 - 32,462,362 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21634,270,548 - 34,290,713 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MOCS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1449,387,923 - 49,399,902 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl449,386,487 - 49,399,928 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660821,727,742 - 1,739,745 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000006731   ⟹   ENSHGLP00000006649
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247596,261,933 - 6,264,578 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000006732   ⟹   ENSHGLP00000006650
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247596,263,125 - 6,271,509 (+)Ensembl
RefSeq Acc Id: XM_021261429   ⟹   XP_021117088
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247596,261,971 - 6,271,509 (+)NCBI
RefSeq Acc Id: XM_021261430   ⟹   XP_021117089
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247596,261,970 - 6,272,246 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021117088 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117089 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB11689 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006650
  ENSHGLP00100042953
GenBank Protein JAO02371 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021117089   ⟸   XM_021261430
- Peptide Label: isoform X2
- UniProtKB: G5BVD5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117088   ⟸   XM_021261429
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JFI3 (UniProtKB/TrEMBL),   G5BVD5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000006649   ⟸   ENSHGLT00000006731
RefSeq Acc Id: ENSHGLP00000006650   ⟸   ENSHGLT00000006732


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004856 Ensembl, ENTREZGENE
  ENSHGLG00100017550 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000006732 ENTREZGENE
  ENSHGLT00100055075 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1170.40 UniProtKB/TrEMBL
InterPro MoaE_sf UniProtKB/TrEMBL
  MOCS2B_euk UniProtKB/TrEMBL
  Mopterin_biosynth_MoaE UniProtKB/TrEMBL
KEGG Report hgl:101701123 UniProtKB/TrEMBL
NCBI Gene Mocs2 ENTREZGENE
PANTHER MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT UniProtKB/TrEMBL
  MOLYBDOPTERIN SYNTHASE RELATED UniProtKB/TrEMBL
Pfam MoaE UniProtKB/TrEMBL
Superfamily-SCOP SSF54690 UniProtKB/TrEMBL
UniProt A0A0P6JFI3 ENTREZGENE, UniProtKB/TrEMBL
  G5BVD5 ENTREZGENE, UniProtKB/TrEMBL