Prss35 (serine protease 35) - Rat Genome Database

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Gene: Prss35 (serine protease 35) Heterocephalus glaber
Analyze
Symbol: Prss35
Name: serine protease 35
RGD ID: 18919997
Description: ENCODES a protein that exhibits peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH genetic disease (ortholog); Hepatomegaly (ortholog); immunodeficiency 23 (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Inactive serine protease 35; protease, serine 35
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479911,082,893 - 11,084,134 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479911,081,734 - 11,092,738 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Prss35
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479911,082,893 - 11,084,134 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479911,081,734 - 11,092,738 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PRSS35
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38683,512,534 - 83,525,704 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl683,512,534 - 83,525,704 (+)EnsemblGRCh38hg38GRCh38
GRCh37684,222,253 - 84,235,423 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36684,278,990 - 84,292,142 (+)NCBINCBI36Build 36hg18NCBI36
Build 34684,278,992 - 84,292,138NCBI
Celera684,655,461 - 84,668,694 (+)NCBICelera
Cytogenetic Map6q14.2NCBI
HuRef681,451,983 - 81,465,072 (+)NCBIHuRef
CHM1_1684,319,778 - 84,333,007 (+)NCBICHM1_1
T2T-CHM13v2.0684,735,749 - 84,748,917 (+)NCBIT2T-CHM13v2.0
Prss35
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39986,625,291 - 86,640,496 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl986,625,702 - 86,640,496 (+)EnsemblGRCm39 Ensembl
GRCm38986,743,240 - 86,758,443 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl986,743,649 - 86,758,443 (+)EnsemblGRCm38mm10GRCm38
MGSCv37986,636,434 - 86,650,680 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36986,539,561 - 86,554,745 (+)NCBIMGSCv36mm8
Celera983,820,968 - 83,834,518 (+)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map946.58NCBI
Prss35
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8896,594,460 - 96,610,992 (+)NCBIGRCr8
mRatBN7.2887,714,449 - 87,731,009 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl887,714,966 - 87,731,009 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx893,395,527 - 93,411,514 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0891,594,739 - 91,610,724 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0889,436,478 - 89,452,400 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0894,423,629 - 94,440,509 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl894,423,808 - 94,440,503 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0893,933,867 - 93,951,103 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4892,009,530 - 92,025,563 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1892,028,984 - 92,045,016 (+)NCBI
Celera887,315,049 - 87,331,109 (+)NCBICelera
Cytogenetic Map8q31NCBI
Prss35
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541111,163,543 - 11,164,689 (+)NCBIChiLan1.0ChiLan1.0
PRSS35
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25103,605,881 - 103,619,114 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16101,502,612 - 101,515,771 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0681,401,423 - 81,414,559 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1684,676,713 - 84,689,861 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl684,687,603 - 84,688,844 (+)Ensemblpanpan1.1panPan2
PRSS35
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11243,892,492 - 43,907,050 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1243,891,652 - 43,905,441 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1243,707,341 - 43,721,782 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01244,661,604 - 44,676,138 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1244,668,430 - 44,674,536 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11244,000,624 - 44,015,154 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01243,933,868 - 43,948,671 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01244,111,376 - 44,125,820 (+)NCBIUU_Cfam_GSD_1.0
Prss35
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494679,043,860 - 79,115,294 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365107,355,705 - 7,427,101 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365107,355,622 - 7,367,139 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRSS35
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl182,714,884 - 82,734,884 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1182,714,880 - 82,734,883 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2192,966,181 - 92,986,027 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRSS35
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1138,188,073 - 8,201,399 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl138,199,146 - 8,200,384 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040184,406,908 - 184,419,839 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000028262   ⟹   ENSHGLP00000027944
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479911,082,893 - 11,084,134 (-)Ensembl
RefSeq Acc Id: XM_004860267   ⟹   XP_004860324
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479911,081,734 - 11,085,239 (-)NCBI
RefSeq Acc Id: XM_004860268   ⟹   XP_004860325
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479911,081,734 - 11,092,738 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004860324 (Get FASTA)   NCBI Sequence Viewer  
  XP_004860325 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB05527 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027944
GenBank Protein JAN96444 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004860325   ⟸   XM_004860268
- UniProtKB: G5B8B6 (UniProtKB/TrEMBL),   A0A0P6K1E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860324   ⟸   XM_004860267
- UniProtKB: G5B8B6 (UniProtKB/TrEMBL),   A0A0P6K1E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000027944   ⟸   ENSHGLT00000028262


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000020052 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000028262 ENTREZGENE
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
KEGG Report hgl:101716208 UniProtKB/TrEMBL
NCBI Gene Prss35 ENTREZGENE
PANTHER INACTIVE SERINE PROTEASE 35 UniProtKB/TrEMBL
  SERINE PROTEASE UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PROSITE TRYPSIN_HIS UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A0P6K1E5 ENTREZGENE, UniProtKB/TrEMBL
  G5B8B6 ENTREZGENE, UniProtKB/TrEMBL