Cpsf7 (cleavage and polyadenylation specific factor 7) - Rat Genome Database

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Gene: Cpsf7 (cleavage and polyadenylation specific factor 7) Heterocephalus glaber
Analyze
Symbol: Cpsf7
Name: cleavage and polyadenylation specific factor 7
RGD ID: 18919576
Description: ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); mRNA 3'-end processing (ortholog); mRNA alternative polyadenylation (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH intellectual disability (ortholog); Joubert syndrome 1 (ortholog); leukocyte adhesion deficiency 3 (ortholog); FOUND IN cytoplasm (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog); mRNA cleavage factor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Cleavage and polyadenylation specificity factor subunit 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624926802,033 - 822,372 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Cpsf7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624926802,033 - 822,372 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CPSF7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,402,729 - 61,429,975 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,402,641 - 61,430,031 (-)EnsemblGRCh38hg38GRCh38
GRCh371161,170,201 - 61,197,447 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,926,777 - 60,953,849 (-)NCBINCBI36Build 36hg18NCBI36
Celera1158,505,642 - 58,532,986 (-)NCBICelera
Cytogenetic Map11q12.2NCBI
HuRef1157,498,010 - 57,525,354 (-)NCBIHuRef
CHM1_11161,053,123 - 61,080,467 (-)NCBICHM1_1
T2T-CHM13v2.01161,391,627 - 61,418,874 (-)NCBIT2T-CHM13v2.0
Cpsf7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,502,594 - 10,525,099 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,502,630 - 10,525,017 (+)EnsemblGRCm39 Ensembl
GRCm381910,525,223 - 10,547,735 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,525,266 - 10,547,653 (+)EnsemblGRCm38mm10GRCm38
MGSCv371910,599,734 - 10,622,225 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,592,311 - 10,614,698 (+)NCBIMGSCv36mm8
Celera1911,221,128 - 11,243,624 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.6NCBI
Cpsf7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,592,745 - 216,616,860 (+)NCBIGRCr8
mRatBN7.21207,167,690 - 207,191,938 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,167,859 - 207,191,905 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,546,294 - 215,570,323 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,601,738 - 222,625,783 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,296,741 - 215,320,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,572,399 - 226,596,185 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,573,105 - 226,596,131 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,518,603 - 233,542,664 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41213,009,572 - 213,032,612 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11213,168,001 - 213,191,028 (+)NCBI
Celera1204,662,017 - 204,685,057 (+)NCBICelera
Cytogenetic Map1q43NCBI
Cpsf7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555116,139,118 - 6,161,130 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555116,139,118 - 6,161,130 (+)NCBIChiLan1.0ChiLan1.0
CPSF7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,570,633 - 62,597,988 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,614,202 - 63,641,631 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,702,510 - 56,729,316 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,065,832 - 60,092,720 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1160,065,832 - 60,092,720 (-)Ensemblpanpan1.1panPan2
CPSF7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,986,709 - 55,012,499 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,986,810 - 55,009,382 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1853,559,662 - 53,585,514 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01856,034,104 - 56,060,195 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1856,034,171 - 56,058,185 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11855,092,629 - 55,118,450 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01854,714,618 - 54,740,435 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01855,594,658 - 55,620,764 (+)NCBIUU_Cfam_GSD_1.0
Cpsf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,515,249 - 11,537,317 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365811,629,041 - 1,651,328 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365811,629,078 - 1,651,147 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPSF7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl210,087,632 - 10,115,076 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1210,087,581 - 10,112,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.229,635,042 - 9,659,648 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CPSF7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,417,452 - 12,445,984 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,417,490 - 12,446,527 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038109,794,801 - 109,823,341 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004874331   ⟹   XP_004874388
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624926802,034 - 822,369 (+)NCBI
RefSeq Acc Id: XM_004874332   ⟹   XP_004874389
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624926802,035 - 822,369 (+)NCBI
RefSeq Acc Id: XM_004874333   ⟹   XP_004874390
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624926802,033 - 822,369 (+)NCBI
RefSeq Acc Id: XM_021251878   ⟹   XP_021107537
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624926802,266 - 822,372 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004874388 (Get FASTA)   NCBI Sequence Viewer  
  XP_004874389 (Get FASTA)   NCBI Sequence Viewer  
  XP_004874390 (Get FASTA)   NCBI Sequence Viewer  
  XP_021107537 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB02072 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026841
RefSeq Acc Id: XP_004874390   ⟸   XM_004874333
- Peptide Label: isoform X3
- UniProtKB: G5AYG1 (UniProtKB/TrEMBL),   A0AAX6QJ25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004874388   ⟸   XM_004874331
- Peptide Label: isoform X1
- UniProtKB: G5AYG1 (UniProtKB/TrEMBL),   A0AAX6QII0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004874389   ⟸   XM_004874332
- Peptide Label: isoform X2
- UniProtKB: G5AYG1 (UniProtKB/TrEMBL),   A0AAX6QII7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021107537   ⟸   XM_021251878
- Peptide Label: isoform X1
- UniProtKB: G5AYG1 (UniProtKB/TrEMBL),   A0AAX6QII0 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019090 ENTREZGENE
Ensembl Transcript ENSHGLT00000027080 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro CPSF6/7 UniProtKB/TrEMBL
  CPSF7_RRM UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
NCBI Gene Cpsf7 ENTREZGENE
PANTHER CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP RNA-binding domain, RBD UniProtKB/TrEMBL
UniProt A0AAX6QII0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QII7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QJ25 ENTREZGENE, UniProtKB/TrEMBL
  G5AYG1 ENTREZGENE, UniProtKB/TrEMBL