Stk35 (serine/threonine kinase 35) - Rat Genome Database

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Gene: Stk35 (serine/threonine kinase 35) Heterocephalus glaber
Analyze
Symbol: Stk35
Name: serine/threonine kinase 35
RGD ID: 18918469
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); ASSOCIATED WITH genetic disease (ortholog); Huntington's disease-like 1 (ortholog); pantothenate kinase-associated neurodegeneration (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase 35
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247413,360,648 - 3,404,734 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247413,360,814 - 3,434,002 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Stk35
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247413,360,648 - 3,404,734 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247413,360,814 - 3,434,002 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
STK35
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38202,101,827 - 2,148,555 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl202,101,827 - 2,177,038 (+)EnsemblGRCh38hg38GRCh38
GRCh37202,082,473 - 2,129,201 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36202,031,519 - 2,077,201 (+)NCBINCBI36Build 36hg18NCBI36
Build 34202,031,518 - 2,077,196NCBI
Celera202,146,462 - 2,193,146 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef202,031,940 - 2,078,604 (+)NCBIHuRef
CHM1_1202,082,728 - 2,129,407 (+)NCBICHM1_1
T2T-CHM13v2.0202,131,852 - 2,178,591 (+)NCBIT2T-CHM13v2.0
Stk35
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392129,642,437 - 129,674,207 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,642,437 - 129,674,207 (+)EnsemblGRCm39 Ensembl
GRCm382129,800,517 - 129,832,287 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,800,517 - 129,832,287 (+)EnsemblGRCm38mm10GRCm38
MGSCv372129,626,253 - 129,658,023 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362129,492,002 - 129,523,728 (+)NCBIMGSCv36mm8
Celera2131,029,084 - 131,060,825 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.19NCBI
Stk35
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83137,465,884 - 137,498,554 (+)NCBIGRCr8
mRatBN7.23117,016,819 - 117,049,131 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,016,950 - 117,048,066 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,914,506 - 120,943,068 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03129,510,126 - 129,538,688 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03127,170,609 - 127,199,165 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03122,307,976 - 122,340,205 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,308,025 - 122,336,468 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03127,676,418 - 127,708,990 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43117,407,255 - 117,435,699 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13117,313,677 - 117,340,795 (+)NCBI
Celera3115,833,698 - 115,862,142 (+)NCBICelera
Cytogenetic Map3q36NCBI
Stk35
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541513,212,152 - 13,249,102 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541513,212,152 - 13,249,097 (+)NCBIChiLan1.0ChiLan1.0
STK35
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2213,091,887 - 3,174,969 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1203,088,818 - 3,171,798 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,214,815 - 2,292,341 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1201,981,355 - 2,028,741 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl201,981,730 - 1,997,556 (+)Ensemblpanpan1.1panPan2
STK35
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,913,746 - 18,958,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,753,651 - 18,958,221 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,742,302 - 18,786,574 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02419,370,768 - 19,415,050 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2419,211,092 - 19,415,035 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,927,273 - 18,971,522 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02419,037,613 - 19,082,068 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02419,366,426 - 19,410,701 (-)NCBIUU_Cfam_GSD_1.0
Stk35
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640167,988,625 - 168,030,131 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648516,423,198 - 16,461,578 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648516,419,989 - 16,462,065 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STK35
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1733,367,349 - 33,412,281 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11733,332,725 - 33,413,328 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21737,735,213 - 37,795,865 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STK35
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1254,382,703 - 54,431,658 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666087799,248 - 846,357 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000013992   ⟹   ENSHGLP00000013851
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247413,360,648 - 3,404,734 (+)Ensembl
RefSeq Acc Id: XM_004840666   ⟹   XP_004840723
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247413,360,814 - 3,404,626 (+)NCBI
RefSeq Acc Id: XM_013070685   ⟹   XP_012926139
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247413,361,754 - 3,404,626 (+)NCBI
RefSeq Acc Id: XM_021254970   ⟹   XP_021110629
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247413,360,814 - 3,434,002 (+)NCBI
RefSeq Acc Id: XM_021254971   ⟹   XP_021110630
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247413,361,514 - 3,404,626 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004840723 (Get FASTA)   NCBI Sequence Viewer  
  XP_012926139 (Get FASTA)   NCBI Sequence Viewer  
  XP_021110629 (Get FASTA)   NCBI Sequence Viewer  
  XP_021110630 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000013851
  ENSHGLP00100000214
Reference Protein Sequences
RefSeq Acc Id: XP_021110629   ⟸   XM_021254970
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JED2 (UniProtKB/TrEMBL),   G5BEP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840723   ⟸   XM_004840666
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JED2 (UniProtKB/TrEMBL),   G5BEP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110630   ⟸   XM_021254971
- Peptide Label: isoform X2
RefSeq Acc Id: XP_012926139   ⟸   XM_013070685
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000013851   ⟸   ENSHGLT00000013992


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009898 Ensembl, ENTREZGENE
  ENSHGLG00100000184 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000013992 ENTREZGENE
  ENSHGLT00100000241 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report hgl:101707534 UniProtKB/TrEMBL
NCBI Gene Stk35 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED UniProtKB/TrEMBL
  SERINE_THREONINE-PROTEIN KINASE 35 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0P6JED2 ENTREZGENE, UniProtKB/TrEMBL
  G5BEP6 ENTREZGENE, UniProtKB/TrEMBL