Rac3 (Rac family small GTPase 3) - Rat Genome Database

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Gene: Rac3 (Rac family small GTPase 3) Heterocephalus glaber
Analyze
Symbol: Rac3
Name: Rac family small GTPase 3
RGD ID: 18918380
Description: ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cell projection assembly (ortholog); cerebral cortex GABAergic interneuron development (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cell periphery (ortholog); endomembrane system (ortholog); filamentous actin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related C3 botulinum toxin substrate 3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,862,502 - 10,864,879 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,862,490 - 10,864,856 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rac3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,862,502 - 10,864,879 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,862,490 - 10,864,856 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RAC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381782,031,678 - 82,034,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1782,031,678 - 82,034,204 (+)EnsemblGRCh38hg38GRCh38
GRCh371779,989,554 - 79,992,080 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,582,821 - 77,585,369 (+)NCBINCBI36Build 36hg18NCBI36
Build 341777,582,820 - 77,585,368NCBI
Celera1776,585,490 - 76,585,771 (+)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,389,767 - 75,392,200 (+)NCBIHuRef
CHM1_11780,075,736 - 80,078,283 (+)NCBICHM1_1
T2T-CHM13v2.01782,898,837 - 82,901,362 (+)NCBIT2T-CHM13v2.0
Rac3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,612,294 - 120,614,795 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,612,296 - 120,614,795 (+)EnsemblGRCm39 Ensembl
GRCm3811120,721,468 - 120,723,969 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,721,470 - 120,723,969 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711120,582,782 - 120,585,283 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,537,558 - 120,540,059 (+)NCBIMGSCv36mm8
Celera11132,456,927 - 132,459,428 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.46NCBI
Rac3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,501,133 - 106,503,569 (+)NCBIGRCr8
mRatBN7.210106,002,808 - 106,005,243 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,993,087 - 106,005,260 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10111,106,804 - 111,109,238 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,569,839 - 110,572,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,923,260 - 105,925,693 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,903,920 - 109,906,596 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,904,259 - 109,906,232 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,496,505 - 109,498,228 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10104,548,128 - 104,549,186 (+)NCBICelera
Cytogenetic Map10q32.3NCBI
Rac3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,137,204 - 1,141,336 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,139,098 - 1,142,443 (-)NCBIChiLan1.0ChiLan1.0
RAC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,566,709 - 98,569,577 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,467,432 - 103,469,986 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,436,264 - 76,439,492 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11782,141,531 - 82,143,623 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1782,133,217 - 82,143,623 (+)Ensemblpanpan1.1panPan2
RAC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19293,260 - 295,990 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha9895,452 - 897,610 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.09886,672 - 888,830 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl9886,673 - 888,831 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.19911,839 - 913,997 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,038,528 - 1,040,685 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,117,115 - 1,119,260 (-)NCBIUU_Cfam_GSD_1.0
Rac3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602881,280 - 884,171 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,528,908 - 5,531,420 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,527,788 - 5,530,694 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl12981,074 - 984,227 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.112981,072 - 984,222 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RAC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,919,086 - 73,921,647 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,919,128 - 73,925,277 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,386,101 - 45,388,661 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000012812   ⟹   ENSHGLP00000012675
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462480110,862,502 - 10,864,879 (+)Ensembl
RefSeq Acc Id: XM_004861000   ⟹   XP_004861057
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480110,862,831 - 10,864,856 (+)NCBI
RefSeq Acc Id: XM_004861001   ⟹   XP_004861058
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480110,862,495 - 10,864,856 (+)NCBI
RefSeq Acc Id: XM_021241117   ⟹   XP_021096776
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480110,862,490 - 10,864,856 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004861057 (Get FASTA)   NCBI Sequence Viewer  
  XP_004861058 (Get FASTA)   NCBI Sequence Viewer  
  XP_021096776 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012675
  ENSHGLP00100017360
GenBank Protein JAO03065 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021096776   ⟸   XM_021241117
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004861058   ⟸   XM_004861001
- Peptide Label: isoform X2
- UniProtKB: A0A0P6K8H6 (UniProtKB/TrEMBL),   G5BF40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861057   ⟸   XM_004861000
- Peptide Label: isoform X1
- UniProtKB: G5BF40 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000012675   ⟸   ENSHGLT00000012812


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009062 Ensembl, ENTREZGENE
  ENSHGLG00100012803 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000012812 ENTREZGENE
  ENSHGLT00100017545 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Rho UniProtKB/TrEMBL
NCBI Gene Rac3 ENTREZGENE
PANTHER PTHR24072 UniProtKB/TrEMBL
  RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3 UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAC1-RELATED UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0P6K8H6 ENTREZGENE, UniProtKB/TrEMBL
  G5BF40 ENTREZGENE, UniProtKB/TrEMBL