Sp7 (Sp7 transcription factor) - Rat Genome Database

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Gene: Sp7 (Sp7 transcription factor) Heterocephalus glaber
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Symbol: Sp7
Name: Sp7 transcription factor
RGD ID: 18918166
Description: ENCODES a protein that exhibits DEAD/H-box RNA helicase binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to zinc ion starvation (ortholog); cementum mineralization (ortholog); diphosphate metabolic process (ortholog); ASSOCIATED WITH aortic valve stenosis (ortholog); osteogenesis imperfecta (ortholog); osteogenesis imperfecta type 12 (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor Sp7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,436,115 - 1,456,609 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,436,390 - 1,444,996 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Sp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,436,115 - 1,456,609 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,436,390 - 1,444,996 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,326,575 - 53,344,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,326,575 - 53,345,315 (-)EnsemblGRCh38hg38GRCh38
GRCh371253,720,359 - 53,738,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,006,626 - 52,015,804 (-)NCBINCBI36Build 36hg18NCBI36
Build 341252,006,628 - 52,015,804NCBI
Celera1253,369,632 - 53,379,307 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,761,885 - 50,771,562 (-)NCBIHuRef
CHM1_11253,687,545 - 53,697,201 (-)NCBICHM1_1
T2T-CHM13v2.01253,292,290 - 53,310,533 (-)NCBIT2T-CHM13v2.0
Sp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,265,038 - 102,275,498 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,265,041 - 102,275,617 (-)EnsemblGRCm39 Ensembl
GRCm3815102,356,603 - 102,367,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,356,606 - 102,367,182 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715102,187,608 - 102,196,702 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,184,644 - 102,194,367 (-)NCBIMGSCv36mm8
Celera15104,514,244 - 104,523,282 (-)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.51NCBI
Sp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,363,193 - 135,373,376 (-)NCBIGRCr8
mRatBN7.27133,484,609 - 133,494,788 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,484,609 - 133,494,847 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,247,146 - 135,255,771 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,476,525 - 137,485,150 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,461,680 - 137,470,323 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,957,316 - 143,967,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,958,858 - 143,967,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,753,826 - 141,762,790 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,109,771 - 141,118,397 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,186,207 - 141,194,213 (-)NCBI
Celera7129,919,226 - 129,927,844 (-)NCBICelera
Cytogenetic Map7q36NCBI
Sp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458583,981 - 602,856 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955458583,981 - 602,856 (-)NCBIChiLan1.0ChiLan1.0
SP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,849,740 - 40,859,601 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,846,505 - 40,856,578 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,409,055 - 35,427,871 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,191,091 - 36,209,494 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,199,673 - 36,209,494 (+)Ensemblpanpan1.1panPan2
SP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,878,612 - 1,887,063 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,880,424 - 1,887,679 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,365,530 - 44,382,281 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,871,509 - 1,888,303 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1271,889,794 - 1,906,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,874,976 - 1,891,740 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,766,164 - 44,782,966 (-)NCBIUU_Cfam_GSD_1.0
Sp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,544,586 - 62,554,293 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,612,060 - 10,619,628 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,610,542 - 10,613,335 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,543,534 - 18,565,776 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,541,368 - 18,566,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,978,684 - 19,002,387 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,436,976 - 49,456,741 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037196,611,275 - 196,624,212 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000001301   ⟹   ENSHGLP00000001259
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249041,436,115 - 1,456,609 (-)Ensembl
RefSeq Acc Id: XM_004872745   ⟹   XP_004872802
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,436,390 - 1,444,323 (-)NCBI
RefSeq Acc Id: XM_021250627   ⟹   XP_021106286
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,436,390 - 1,444,996 (-)NCBI
RefSeq Acc Id: XM_021250628   ⟹   XP_021106287
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,436,390 - 1,444,996 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004872802 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106286 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106287 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001259
GenBank Protein JAO00751 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021106287   ⟸   XM_021250628
- Peptide Label: isoform X2
- UniProtKB: A0AAX6S8C5 (UniProtKB/TrEMBL),   A0A0P6JHT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106286   ⟸   XM_021250627
- Peptide Label: isoform X1
- UniProtKB: A0AAX6SA42 (UniProtKB/TrEMBL),   A0A0P6JHT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872802   ⟸   XM_004872745
- Peptide Label: isoform X1
- UniProtKB: A0AAX6SA42 (UniProtKB/TrEMBL),   A0A0P6JHT8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000001259   ⟸   ENSHGLT00000001301


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000980 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000001301 ENTREZGENE
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Sp7 ENTREZGENE
PANTHER KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR SP7 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A0P6JHT8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S8C5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SA42 ENTREZGENE, UniProtKB/TrEMBL