Foxo6 (forkhead box O6) - Rat Genome Database

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Gene: Foxo6 (forkhead box O6) Heterocephalus glaber
Analyze
Symbol: Foxo6
Name: forkhead box O6
RGD ID: 18917531
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN memory (ortholog); positive regulation of dendritic spine development (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Forkhead box protein O6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624892745,410 - 766,247 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624892621,308 - 766,187 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleus  (IEA)

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Foxo6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624892745,410 - 766,247 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624892621,308 - 766,187 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FOXO6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38141,361,434 - 41,383,590 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl141,361,922 - 41,383,590 (+)EnsemblGRCh38hg38GRCh38
GRCh37141,827,106 - 41,849,262 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36141,599,814 - 41,620,940 (+)NCBINCBI36Build 36hg18NCBI36
Celera140,110,528 - 40,132,021 (+)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef139,943,994 - 40,007,076 (+)NCBIHuRef
CHM1_1141,943,469 - 41,965,188 (+)NCBICHM1_1
T2T-CHM13v2.0141,230,844 - 41,253,232 (+)NCBIT2T-CHM13v2.0
Foxo6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394120,124,275 - 120,144,458 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4120,124,276 - 120,144,546 (-)EnsemblGRCm39 Ensembl
GRCm384120,267,078 - 120,287,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4120,267,079 - 120,287,349 (-)EnsemblGRCm38mm10GRCm38
MGSCv374119,939,683 - 119,959,866 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364119,764,713 - 119,784,896 (-)NCBIMGSCv36mm8
Celera4118,982,910 - 119,003,192 (-)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map456.1NCBI
Foxo6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85139,141,329 - 139,161,629 (-)NCBIGRCr8
mRatBN7.25133,856,087 - 133,876,387 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5133,856,072 - 133,876,573 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5136,583,867 - 136,604,179 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05138,340,315 - 138,360,627 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05138,360,926 - 138,381,241 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05139,208,153 - 139,227,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5139,208,046 - 139,227,196 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05142,993,815 - 143,013,470 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45140,846,863 - 140,866,841 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5132,414,382 - 132,433,256 (-)NCBICelera
Cytogenetic Map5q36NCBI
Foxo6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555371,109,450 - 1,128,410 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555371,108,711 - 1,129,287 (+)NCBIChiLan1.0ChiLan1.0
FOXO6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21185,430,057 - 185,452,631 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11184,572,057 - 184,594,622 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0140,659,371 - 40,681,778 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1141,975,717 - 41,997,356 (+)NCBIpanpan1.1PanPan1.1panPan2
FOXO6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1151,760,034 - 1,772,224 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha152,009,227 - 2,029,237 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0151,839,874 - 1,859,925 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl151,839,017 - 1,859,925 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1151,746,136 - 1,766,138 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0151,818,655 - 1,825,319 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0151,821,621 - 1,841,651 (-)NCBIUU_Cfam_GSD_1.0
Foxo6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505857,118,448 - 57,139,436 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647422,943,385 - 22,963,288 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647422,943,231 - 22,964,208 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXO6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6169,858,603 - 169,880,069 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16169,858,711 - 169,880,005 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FOXO6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12091,527,355 - 91,549,530 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603325,329,970 - 25,352,600 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000004819   ⟹   ENSHGLP00000004756
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624892745,410 - 766,247 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000004820   ⟹   ENSHGLP00000004757
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624892745,773 - 765,292 (+)Ensembl
RefSeq Acc Id: XM_004871805   ⟹   XP_004871862
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624892745,394 - 766,187 (+)NCBI
RefSeq Acc Id: XM_021249917   ⟹   XP_021105576
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624892745,387 - 766,187 (+)NCBI
RefSeq Acc Id: XM_021249918   ⟹   XP_021105577
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624892621,308 - 766,187 (+)NCBI
RefSeq Acc Id: XM_021249919   ⟹   XP_021105578
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624892621,308 - 766,187 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004871862 (Get FASTA)   NCBI Sequence Viewer  
  XP_021105576 (Get FASTA)   NCBI Sequence Viewer  
  XP_021105577 (Get FASTA)   NCBI Sequence Viewer  
  XP_021105578 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99305 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004756
Reference Protein Sequences
RefSeq Acc Id: XP_021105578   ⟸   XM_021249919
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021105577   ⟸   XM_021249918
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021105576   ⟸   XM_021249917
- Peptide Label: isoform X1
- UniProtKB: G5AQJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004871862   ⟸   XM_004871805
- Peptide Label: isoform X2
- UniProtKB: G5AQJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000004756   ⟸   ENSHGLT00000004819
RefSeq Acc Id: ENSHGLP00000004757   ⟸   ENSHGLT00000004820


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003494 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004819 ENTREZGENE
Gene3D-CATH 6.10.250.1690 UniProtKB/TrEMBL
  Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain UniProtKB/TrEMBL
InterPro FH_FOXO6 UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/TrEMBL
  FOXO-TAD UniProtKB/TrEMBL
  FOXO_KIX-bd UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Foxo6 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN O UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN O6 UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
  FOXO-TAD UniProtKB/TrEMBL
  FOXO_KIX_bdg UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP Winged helix' DNA-binding domain UniProtKB/TrEMBL
UniProt G5AQJ5 ENTREZGENE, UniProtKB/TrEMBL