Psme4 (proteasome activator subunit 4) - Rat Genome Database

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Gene: Psme4 (proteasome activator subunit 4) Heterocephalus glaber
Analyze
Symbol: Psme4
Name: proteasome activator subunit 4
RGD ID: 18917162
Description: ENCODES a protein that exhibits lysine-acetylated histone binding (inferred); peptidase activator activity (inferred); proteasome binding (inferred); INVOLVED IN DNA damage response (ortholog); sperm DNA condensation (ortholog); ASSOCIATED WITH genetic disease (ortholog); human immunodeficiency virus infectious disease (ortholog); visceral heterotaxy (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proteasome activator complex subunit 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248338,035,768 - 8,137,635 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248338,035,768 - 8,137,655 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Psme4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248338,035,768 - 8,137,635 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248338,035,768 - 8,137,655 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PSME4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38253,864,069 - 53,970,993 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl253,864,069 - 53,970,993 (-)EnsemblGRCh38hg38GRCh38
GRCh37254,091,206 - 54,198,130 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36253,945,075 - 54,051,354 (-)NCBINCBI36Build 36hg18NCBI36
Celera253,932,066 - 54,038,835 (-)NCBICelera
Cytogenetic Map2p16.2NCBI
HuRef253,825,271 - 53,932,895 (-)NCBIHuRef
CHM1_1254,022,073 - 54,128,847 (-)NCBICHM1_1
T2T-CHM13v2.0253,860,299 - 53,967,209 (-)NCBIT2T-CHM13v2.0
Psme4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,721,753 - 30,831,150 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1130,721,726 - 30,830,361 (+)EnsemblGRCm39 Ensembl
GRCm381130,771,775 - 30,881,150 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,771,726 - 30,880,361 (+)EnsemblGRCm38mm10GRCm38
MGSCv371130,671,775 - 30,780,361 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361130,672,062 - 30,779,734 (+)NCBIMGSCv36mm8
Celera1133,168,570 - 33,283,768 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.16NCBI
Psme4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814108,706,643 - 108,810,330 (+)NCBIGRCr8
mRatBN7.214104,505,716 - 104,609,410 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14104,505,716 - 104,609,408 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14108,818,138 - 108,921,679 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014110,051,006 - 110,154,642 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014106,523,441 - 106,627,083 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014115,166,165 - 115,269,041 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14115,166,416 - 115,269,056 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014114,823,668 - 114,926,544 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414111,892,871 - 111,997,184 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera14103,343,958 - 103,447,595 (+)NCBICelera
Cytogenetic Map14q22NCBI
Psme4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544119,588,597 - 19,663,334 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544119,586,567 - 19,663,335 (-)NCBIChiLan1.0ChiLan1.0
PSME4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21272,388,312 - 72,494,427 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A72,389,323 - 72,498,394 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A54,007,224 - 54,113,557 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A54,919,092 - 55,024,551 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A54,919,094 - 55,024,551 (-)Ensemblpanpan1.1panPan2
PSME4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11054,873,093 - 54,960,030 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1054,875,177 - 54,960,035 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1054,825,071 - 54,930,068 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01055,872,471 - 55,977,527 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1055,873,191 - 55,977,522 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11055,564,953 - 55,669,738 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01055,851,799 - 55,956,529 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01056,138,193 - 56,243,273 (-)NCBIUU_Cfam_GSD_1.0
Psme4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629228,067,509 - 28,166,371 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936491404,912 - 504,326 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936491404,921 - 503,783 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSME4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl387,231,755 - 87,337,703 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1387,231,510 - 87,337,709 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2392,436,939 - 92,489,023 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSME4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11452,999,960 - 53,108,624 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1452,999,960 - 53,108,885 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604558,594,269 - 58,700,839 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000027364   ⟹   ENSHGLP00000027124
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248338,035,768 - 8,137,635 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000027365   ⟹   ENSHGLP00000027125
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248338,037,826 - 8,137,519 (-)Ensembl
RefSeq Acc Id: XM_004867295   ⟹   XP_004867352
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248338,035,768 - 8,137,655 (-)NCBI
RefSeq Acc Id: XM_013066450   ⟹   XP_012921904
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248338,035,768 - 8,137,655 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004867352 (Get FASTA)   NCBI Sequence Viewer  
  XP_012921904 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027124
Reference Protein Sequences
RefSeq Acc Id: XP_012921904   ⟸   XM_013066450
- Peptide Label: isoform X2
- UniProtKB: G5B8U9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004867352   ⟸   XM_004867295
- Peptide Label: isoform X1
- UniProtKB: G5B8U9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000027124   ⟸   ENSHGLT00000027364
RefSeq Acc Id: ENSHGLP00000027125   ⟸   ENSHGLT00000027365


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019292 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000027364 ENTREZGENE
Gene3D-CATH Leucine-rich Repeat Variant UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Blm10_mid UniProtKB/TrEMBL
  PSME4 UniProtKB/TrEMBL
  PSME4_C UniProtKB/TrEMBL
NCBI Gene Psme4 ENTREZGENE
PANTHER PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 UniProtKB/TrEMBL
  PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 UniProtKB/TrEMBL
Pfam BLM10_mid UniProtKB/TrEMBL
  DUF3437 UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
UniProt G5B8U9 ENTREZGENE, UniProtKB/TrEMBL