Mctp1 (multiple C2 and transmembrane domain containing 1) - Rat Genome Database

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Gene: Mctp1 (multiple C2 and transmembrane domain containing 1) Heterocephalus glaber
Analyze
Symbol: Mctp1
Name: multiple C2 and transmembrane domain containing 1
RGD ID: 18917095
Description: ENCODES a protein that exhibits calcium-dependent phospholipid binding (ortholog); INVOLVED IN negative regulation of cell migration (ortholog); negative regulation of endocytosis (ortholog); negative regulation of response to oxidative stress (ortholog); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN recycling endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: multiple C2 and transmembrane domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474313,405,481 - 13,919,373 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474313,401,767 - 13,919,388 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mctp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474313,405,481 - 13,919,373 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474313,401,767 - 13,919,388 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MCTP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38594,703,690 - 95,285,094 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl594,703,690 - 95,285,094 (-)EnsemblGRCh38hg38GRCh38
GRCh37594,039,395 - 94,620,798 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36594,068,957 - 94,646,035 (-)NCBINCBI36Build 36hg18NCBI36
Celera589,904,181 - 90,498,783 (-)NCBICelera
Cytogenetic Map5q15NCBI
HuRef589,215,571 - 89,810,232 (-)NCBIHuRef
CHM1_1593,474,921 - 94,052,972 (-)NCBICHM1_1
T2T-CHM13v2.0595,188,075 - 95,786,099 (-)NCBIT2T-CHM13v2.0
Mctp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391376,530,481 - 77,181,403 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1376,532,259 - 77,179,929 (+)EnsemblGRCm39 Ensembl
GRCm381376,382,362 - 77,033,284 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1376,384,535 - 77,031,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv371376,522,409 - 77,171,071 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361376,850,963 - 77,495,357 (+)NCBIMGSCv36mm8
Celera1378,709,211 - 79,357,429 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.98NCBI
Mctp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr827,798,968 - 8,493,596 (+)NCBIGRCr8
mRatBN7.226,071,408 - 6,761,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl26,065,808 - 6,761,833 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx213,149,950 - 13,873,885 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0211,249,210 - 11,973,165 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.025,914,158 - 6,608,224 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.023,400,883 - 4,089,949 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl23,400,977 - 4,088,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.023,398,033 - 4,086,933 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.423,652,722 - 4,354,754 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.123,941,173 - 4,377,606 (+)NCBI
Celera22,535,961 - 3,220,251 (+)NCBICelera
Cytogenetic Map2q11NCBI
Mctp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541817,229,498 - 17,745,010 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541817,229,498 - 17,746,936 (+)NCBIChiLan1.0ChiLan1.0
MCTP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2420,100,647 - 20,697,607 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1518,254,259 - 18,851,219 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0520,071,072 - 20,669,826 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1520,215,984 - 20,808,014 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl520,215,917 - 20,808,014 (+)Ensemblpanpan1.1panPan2
MCTP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1314,255,685 - 14,782,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl314,358,134 - 14,780,801 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha315,594,036 - 16,121,093 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0314,133,526 - 14,662,420 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl314,133,527 - 14,682,475 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1314,098,067 - 14,625,300 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0314,095,557 - 14,623,822 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0314,295,164 - 14,827,487 (+)NCBIUU_Cfam_GSD_1.0
Mctp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213169,864,546 - 170,367,862 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365238,050,006 - 8,553,432 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365238,050,001 - 8,553,427 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCTP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2101,384,910 - 101,920,111 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12101,384,904 - 101,920,152 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22104,928,439 - 105,217,494 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCTP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1488,581,761 - 89,174,995 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl488,585,446 - 88,967,701 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604937,226,961 - 37,820,001 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004841689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013071111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013071112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021255780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021255781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01021599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01021615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01003410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000007364   ⟹   ENSHGLP00000007279
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474313,405,481 - 13,747,502 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000007365   ⟹   ENSHGLP00000007280
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474313,405,516 - 13,919,373 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000007366   ⟹   ENSHGLP00000007281
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474313,579,682 - 13,747,502 (-)Ensembl
RefSeq Acc Id: XM_004841689   ⟹   XP_004841746
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474313,401,767 - 13,919,388 (-)NCBI
RefSeq Acc Id: XM_013071111   ⟹   XP_012926565
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474313,401,767 - 13,747,284 (-)NCBI
RefSeq Acc Id: XM_013071112   ⟹   XP_012926566
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474313,401,767 - 13,747,284 (-)NCBI
RefSeq Acc Id: XM_021255780   ⟹   XP_021111439
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474313,401,767 - 13,919,388 (-)NCBI
RefSeq Acc Id: XM_021255781   ⟹   XP_021111440
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474313,401,767 - 13,919,388 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021111440   ⟸   XM_021255781
- Peptide Label: isoform X3
- UniProtKB: G5BU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111439   ⟸   XM_021255780
- Peptide Label: isoform X2
- UniProtKB: G5BU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841746   ⟸   XM_004841689
- Peptide Label: isoform X1
- UniProtKB: G5BU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926566   ⟸   XM_013071112
- Peptide Label: isoform X5
- UniProtKB: G5BU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926565   ⟸   XM_013071111
- Peptide Label: isoform X4
- UniProtKB: A0A0P6J9S3 (UniProtKB/TrEMBL),   G5BU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000007279   ⟸   ENSHGLT00000007364
RefSeq Acc Id: ENSHGLP00000007280   ⟸   ENSHGLT00000007365
RefSeq Acc Id: ENSHGLP00000007281   ⟸   ENSHGLT00000007366


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005301 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100013604 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000007364 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00000007365 ENTREZGENE
  ENSHGLT00100018647 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  PRibTrfase_C UniProtKB/TrEMBL
NCBI Gene Mctp1 ENTREZGENE
PANTHER C2 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  DYSFERLIN-RELATED UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  PRT_C UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A0P6J9S3 ENTREZGENE, UniProtKB/TrEMBL
  G5BU36 ENTREZGENE, UniProtKB/TrEMBL