Pard6a (par-6 family cell polarity regulator alpha) - Rat Genome Database

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Gene: Pard6a (par-6 family cell polarity regulator alpha) Heterocephalus glaber
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Symbol: Pard6a
Name: par-6 family cell polarity regulator alpha
RGD ID: 18916937
Description: ENCODES a protein that exhibits GTP-dependent protein binding (inferred); small GTPase binding (inferred); INVOLVED IN negative regulation of protein phosphorylation (ortholog); regulation of cellular localization (ortholog); PARTICIPATES IN adenosine signaling pathway; insulin signaling pathway; protein kinase C (PKC) signaling pathway; ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); Chromosome 16q12 Duplication Syndrome (ortholog); chromosome 16q22 deletion syndrome (ortholog); FOUND IN axonal growth cone (ortholog); neuronal cell body (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: par-6 partitioning defective 6 homolog alpha; partitioning defective 6 homolog alpha; Partitioning defective 6-like protein alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,686,921 - 18,688,703 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,686,916 - 18,688,739 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Pard6a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,686,921 - 18,688,703 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,686,916 - 18,688,739 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PARD6A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,660,960 - 67,662,774 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,660,946 - 67,662,774 (+)EnsemblGRCh38hg38GRCh38
GRCh371667,694,863 - 67,696,677 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,252,352 - 66,254,182 (+)NCBINCBI36Build 36hg18NCBI36
Build 341666,252,362 - 66,254,177NCBI
Celera1652,203,341 - 52,205,171 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,567,763 - 53,569,593 (+)NCBIHuRef
CHM1_11669,102,564 - 69,104,394 (+)NCBICHM1_1
T2T-CHM13v2.01673,455,728 - 73,457,542 (+)NCBIT2T-CHM13v2.0
Pard6a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,427,780 - 106,430,126 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,427,780 - 106,430,128 (+)EnsemblGRCm39 Ensembl
GRCm388105,701,148 - 105,703,494 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,701,148 - 105,703,496 (+)EnsemblGRCm38mm10GRCm38
MGSCv378108,225,054 - 108,227,394 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,590,812 - 108,592,595 (+)NCBIMGSCv36mm8
Celera8109,926,072 - 109,928,412 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Pard6a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,499,420 - 50,502,301 (+)NCBIGRCr8
mRatBN7.21933,589,531 - 33,591,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,589,542 - 33,591,900 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,405,102 - 40,407,471 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,058,434 - 41,060,803 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,356,207 - 43,358,576 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,668,133 - 37,670,450 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,668,133 - 37,672,729 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,534,837 - 48,537,154 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,533,395 - 35,535,711 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,538,275 - 35,540,592 (+)NCBI
Celera1933,017,530 - 33,019,847 (+)NCBICelera
Cytogenetic Map19q12NCBI
Pard6a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,019,929 - 9,021,995 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554849,019,929 - 9,022,561 (-)NCBIChiLan1.0ChiLan1.0
PARD6A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,189,120 - 77,190,952 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,101,588 - 83,103,415 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,004,822 - 48,006,656 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,394,252 - 67,395,991 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,394,252 - 67,395,991 (+)Ensemblpanpan1.1panPan2
PARD6A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,787,424 - 81,789,833 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,787,553 - 81,790,324 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,777,186 - 81,779,574 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,222,592 - 82,224,980 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,222,721 - 82,225,620 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,048,921 - 82,051,309 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,730,456 - 81,732,843 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,373,005 - 82,375,393 (-)NCBIUU_Cfam_GSD_1.0
Pard6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,533,814 - 41,536,924 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647518,052,181 - 18,054,620 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647518,052,768 - 18,054,620 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARD6A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,280,502 - 28,283,788 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,280,502 - 28,282,923 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PARD6A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,781,890 - 59,783,990 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604722,535,640 - 22,537,747 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026321   ⟹   ENSHGLP00000026090
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474618,686,921 - 18,688,703 (-)Ensembl
RefSeq Acc Id: XM_004843019   ⟹   XP_004843076
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474618,686,916 - 18,688,739 (-)NCBI
RefSeq Acc Id: XM_004843020   ⟹   XP_004843077
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474618,686,916 - 18,688,739 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004843076 (Get FASTA)   NCBI Sequence Viewer  
  XP_004843077 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB17029 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026090
  ENSHGLP00000044040
GenBank Protein JAO03282 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004843077   ⟸   XM_004843020
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JIJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004843076   ⟸   XM_004843019
- Peptide Label: isoform X1
- UniProtKB: G5C668 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000026090   ⟸   ENSHGLT00000026321


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018571 Ensembl, ENTREZGENE
  ENSHGLG00000035759 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000026321 ENTREZGENE
  ENSHGLT00000079538 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro PAR6_homolog UniProtKB/TrEMBL
  PB1-like UniProtKB/TrEMBL
  PB1_dom UniProtKB/TrEMBL
  PB1_Par6 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
KEGG Report hgl:101707435 UniProtKB/TrEMBL
NCBI Gene Pard6a ENTREZGENE
PANTHER PAR-6-RELATED UniProtKB/TrEMBL
  PTHR14102:SF9 UniProtKB/TrEMBL
Pfam PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PROSITE PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP CAD & PB1 domains UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A0P6JIJ0 ENTREZGENE, UniProtKB/TrEMBL
  G5C668 ENTREZGENE, UniProtKB/TrEMBL