Dxo (decapping exoribonuclease) - Rat Genome Database

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Gene: Dxo (decapping exoribonuclease) Heterocephalus glaber
Analyze
Symbol: Dxo (Ensembl: DOM3Z)
Name: decapping exoribonuclease
RGD ID: 18916610
Description: ENCODES a protein that exhibits 5'-3' exonuclease activity (ortholog); magnesium ion binding (ortholog); mRNA binding (ortholog); INVOLVED IN mRNA catabolic process (ortholog); nuclear mRNA surveillance (ortholog); RNA destabilization (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH proteasome-associated autoinflammatory syndrome 1 (ortholog); FOUND IN nucleoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: decapping and exoribonuclease protein; dom-3 homolog Z; Dom3z
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,281,101 - 24,287,647 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,281,099 - 24,283,403 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
nucleoplasm  (ISO)
nucleus  (IEA)
plasma membrane  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dxo
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,281,101 - 24,287,647 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,281,099 - 24,283,403 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DXO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,969,815 - 31,972,138 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,969,810 - 31,972,290 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,937,592 - 31,939,915 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,045,567 - 32,048,011 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,045,566 - 32,048,011NCBI
Celera633,537,350 - 33,539,794 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,724,525 - 31,726,969 (-)NCBIHuRef
CHM1_1631,939,669 - 31,942,113 (-)NCBICHM1_1
T2T-CHM13v2.0631,823,020 - 31,825,343 (-)NCBIT2T-CHM13v2.0
Dxo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,055,998 - 35,058,162 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,055,995 - 35,058,209 (+)EnsemblGRCm39 Ensembl
GRCm381734,836,996 - 34,839,187 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,837,019 - 34,839,233 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,973,964 - 34,976,131 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,445,139 - 34,447,289 (+)NCBIMGSCv36mm8
Celera1737,932,348 - 37,934,515 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.39NCBI
Dxo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,997,953 - 4,000,115 (-)NCBIGRCr8
mRatBN7.2203,993,322 - 3,995,484 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,993,327 - 3,995,494 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,693,280 - 4,695,364 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,055,028 - 4,057,112 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,592,209 - 4,594,293 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,517,307 - 4,519,391 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,517,307 - 4,519,389 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,597,106 - 6,599,190 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,093,718 - 4,095,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,093,893 - 4,096,049 (-)NCBI
Celera204,035,291 - 4,037,375 (+)NCBICelera
Cytogenetic Map20p12NCBI
Dxo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437481,554 - 484,989 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437482,866 - 484,989 (-)NCBIChiLan1.0ChiLan1.0
DXO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,446,379 - 46,448,629 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,407,867 - 42,410,121 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,630,523 - 31,632,363 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,517,086 - 32,519,566 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,517,086 - 32,519,566 (-)Ensemblpanpan1.1panPan2
DXO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,424,584 - 1,426,275 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,424,591 - 1,426,452 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,559,785 - 1,562,016 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,566,885 - 1,568,996 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,566,892 - 1,568,726 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,424,344 - 1,426,575 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,492,527 - 1,494,758 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,559,127 - 1,561,358 (-)NCBIUU_Cfam_GSD_1.0
Dxo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,982,182 - 35,984,452 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,576,886 - 1,579,154 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,576,823 - 1,579,158 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DXO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,056,525 - 24,059,997 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,057,670 - 24,060,108 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,752,093 - 27,754,531 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DXO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,049,679 - 40,052,114 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,050,257 - 40,052,050 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,886,210 - 31,888,644 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000023481   ⟹   ENSHGLP00000023265
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475424,281,101 - 24,287,647 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000023482   ⟹   ENSHGLP00000023266
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475424,281,563 - 24,287,647 (+)Ensembl
RefSeq Acc Id: XM_004846920   ⟹   XP_004846977
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475424,281,106 - 24,283,403 (+)NCBI
RefSeq Acc Id: XM_004846921   ⟹   XP_004846978
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475424,281,111 - 24,283,403 (+)NCBI
RefSeq Acc Id: XM_021260074   ⟹   XP_021115733
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475424,281,099 - 24,283,403 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846977 (Get FASTA)   NCBI Sequence Viewer  
  XP_004846978 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115733 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023265
  ENSHGLP00000023266
RefSeq Acc Id: XP_021115733   ⟸   XM_021260074
- Peptide Label: isoform X3
- UniProtKB: G5C3H4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004846977   ⟸   XM_004846920
- Peptide Label: isoform X1
- UniProtKB: G5C3H4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004846978   ⟸   XM_004846921
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J964 (UniProtKB/TrEMBL),   G5C3H4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000023266   ⟸   ENSHGLT00000023482
Ensembl Acc Id: ENSHGLP00000023265   ⟸   ENSHGLT00000023481


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016585 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023481 ENTREZGENE
  ENSHGLT00000023482 ENTREZGENE
InterPro RAI1 UniProtKB/TrEMBL
  RAI1-like_fam UniProtKB/TrEMBL
NCBI Gene Dxo ENTREZGENE
PANTHER DECAPPING AND EXORIBONUCLEASE PROTEIN UniProtKB/TrEMBL
  PTHR12395 UniProtKB/TrEMBL
Pfam RAI1 UniProtKB/TrEMBL
UniProt A0A0P6J964 ENTREZGENE, UniProtKB/TrEMBL
  G5C3H4 ENTREZGENE, UniProtKB/TrEMBL