Brwd1 (bromodomain and WD repeat domain containing 1) - Rat Genome Database

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Gene: Brwd1 (bromodomain and WD repeat domain containing 1) Heterocephalus glaber
Analyze
Symbol: Brwd1
Name: bromodomain and WD repeat domain containing 1
RGD ID: 18916534
Description: INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); male infertility (ortholog); FOUND IN axoneme (ortholog); cytosol (ortholog); motile cilium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bromodomain and WD repeat-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474524,700,822 - 24,850,041 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axoneme  (ISO)
cytosol  (ISO)
motile cilium  (ISO)
nucleolus  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Brwd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474524,700,822 - 24,850,041 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BRWD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382139,184,176 - 39,321,212 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2139,184,176 - 39,321,559 (-)EnsemblGRCh38hg38GRCh38
GRCh372140,556,102 - 40,685,558 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362139,479,274 - 39,607,426 (-)NCBINCBI36Build 36hg18NCBI36
Build 342139,484,018 - 39,607,426NCBI
Celera2125,755,073 - 25,883,187 (-)NCBICelera
Cytogenetic Map21q22.2NCBI
HuRef2126,027,732 - 26,155,294 (-)NCBIHuRef
CHM1_12140,118,763 - 40,246,909 (-)NCBICHM1_1
T2T-CHM13v2.02137,568,748 - 37,705,729 (-)NCBIT2T-CHM13v2.0
Brwd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391695,793,289 - 95,883,905 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1695,793,292 - 95,883,726 (-)EnsemblGRCm39 Ensembl
GRCm381695,992,089 - 96,082,703 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1695,992,092 - 96,082,526 (-)EnsemblGRCm38mm10GRCm38
MGSCv371696,213,699 - 96,304,035 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361696,097,357 - 96,187,336 (-)NCBIMGSCv36mm8
Celera1697,066,204 - 97,156,016 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1656.77NCBI
Brwd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,756,174 - 48,853,692 (-)NCBIGRCr8
mRatBN7.21135,286,364 - 35,378,768 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,288,313 - 35,378,768 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,950,645 - 44,035,956 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01136,622,022 - 36,707,333 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,767,803 - 35,853,171 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01136,338,080 - 36,430,473 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1136,337,635 - 36,430,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,868,355 - 39,961,118 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,303,503 - 36,385,878 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11136,360,190 - 36,443,550 (-)NCBI
Celera1133,077,458 - 33,183,375 (+)NCBICelera
Cytogenetic Map11q11NCBI
Brwd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540738,003,386 - 38,107,958 (-)NCBIChiLan1.0ChiLan1.0
BRWD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22235,286,126 - 35,420,317 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12130,143,922 - 30,276,149 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02125,535,009 - 25,666,943 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12138,886,009 - 39,001,390 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,896,768 - 39,002,805 (-)Ensemblpanpan1.1panPan2
BRWD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13134,122,477 - 34,240,555 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3134,122,463 - 34,240,639 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3133,234,759 - 33,354,028 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03133,468,719 - 33,587,748 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3133,455,704 - 33,587,841 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13133,341,959 - 33,460,975 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03133,346,073 - 33,465,317 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03133,836,495 - 33,956,003 (-)NCBIUU_Cfam_GSD_1.0
Brwd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497133,470,876 - 33,594,248 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365003,873,615 - 3,984,523 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365003,873,570 - 3,995,725 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRWD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13202,777,305 - 202,896,509 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113202,776,040 - 202,896,545 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213212,916,565 - 212,952,696 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BRWD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1283,115,290 - 83,245,798 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl283,113,757 - 83,230,423 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605410,971,963 - 11,104,909 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004842365   ⟹   XP_004842422
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474524,700,823 - 24,850,041 (+)NCBI
RefSeq Acc Id: XM_021256241   ⟹   XP_021111900
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474524,700,822 - 24,850,041 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004842422 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111900 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00100045813
GenBank Protein JAN99163 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021111900   ⟸   XM_021256241
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JV55 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842422   ⟸   XM_004842365
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JV55 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00100013483 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00100063777 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  2.30.30.1040 UniProtKB/TrEMBL
InterPro Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Brwd1 ENTREZGENE
PANTHER BRWD3 UniProtKB/TrEMBL
  WD REPEAT DOMAIN 9 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF47370 UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
UniProt A0A0P6JV55 ENTREZGENE, UniProtKB/TrEMBL