Parp14 (poly(ADP-ribose) polymerase family member 14) - Rat Genome Database

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Gene: Parp14 (poly(ADP-ribose) polymerase family member 14) Heterocephalus glaber
Analyze
Symbol: Parp14
Name: poly(ADP-ribose) polymerase family member 14
RGD ID: 18916365
Description: ENCODES a protein that exhibits enzyme binding (ortholog); NAD+ binding (ortholog); INVOLVED IN negative regulation of type II interferon-mediated signaling pathway (ortholog); negative regulation of tyrosine phosphorylation of STAT protein (ortholog); positive regulation of interleukin-4-mediated signaling pathway (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; interleukin-4 signaling pathway; ASSOCIATED WITH alkaptonuria (ortholog); familial hypocalciuric hypercalcemia (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly (ADP-ribose) polymerase 14; poly [ADP-ribose] polymerase 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912969,236 - 1,023,564 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912969,144 - 1,022,506 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
nucleus  (IEA)
plasma membrane  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Parp14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912969,236 - 1,023,564 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912969,144 - 1,022,506 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PARP14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383122,680,839 - 122,730,840 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3122,680,839 - 122,730,840 (+)EnsemblGRCh38hg38GRCh38
GRCh373122,399,686 - 122,449,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,882,362 - 123,932,377 (+)NCBINCBI36Build 36hg18NCBI36
Build 343123,900,859 - 123,932,376NCBI
Celera3120,809,505 - 120,859,520 (+)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3119,772,932 - 119,822,958 (+)NCBIHuRef
CHM1_13122,363,227 - 122,413,244 (+)NCBICHM1_1
T2T-CHM13v2.03125,400,088 - 125,450,091 (+)NCBIT2T-CHM13v2.0
Parp14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391635,652,262 - 35,691,904 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1635,653,244 - 35,691,914 (-)EnsemblGRCm39 Ensembl
GRCm381635,831,892 - 35,871,518 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,832,874 - 35,871,544 (-)EnsemblGRCm38mm10GRCm38
MGSCv371635,832,964 - 35,871,468 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,752,625 - 35,791,247 (-)NCBIMGSCv36mm8
Celera1636,312,784 - 36,351,557 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.43NCBI
Parp14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,408,134 - 78,440,201 (+)NCBIGRCr8
mRatBN7.21164,902,848 - 64,934,916 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,902,785 - 64,934,916 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1173,724,829 - 73,756,951 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,387,099 - 66,419,216 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,418,357 - 65,450,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,105,442 - 68,137,509 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,105,369 - 68,137,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,194,913 - 71,226,980 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41166,736,902 - 66,768,977 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11166,800,714 - 66,824,843 (+)NCBI
Celera1164,365,191 - 64,397,200 (+)NCBICelera
Cytogenetic Map11q22NCBI
Parp14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,879,740 - 21,927,883 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,878,980 - 21,929,097 (+)NCBIChiLan1.0ChiLan1.0
PARP14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,630,429 - 120,680,952 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13120,635,379 - 120,685,731 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03119,773,334 - 119,823,732 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13126,677,868 - 126,728,256 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3126,677,868 - 126,728,256 (+)Ensemblpanpan1.1panPan2
PARP14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13325,763,282 - 25,798,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3325,763,255 - 25,798,198 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3325,787,251 - 25,824,358 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03325,996,942 - 26,033,819 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,996,843 - 26,031,731 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13325,794,923 - 25,831,746 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03325,836,951 - 25,874,257 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,396,287 - 26,433,388 (+)NCBIUU_Cfam_GSD_1.0
LOC101962583
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602128,548,280 - 128,598,605 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,923,411 - 8,974,283 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,923,398 - 8,976,583 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARP14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13137,809,510 - 137,865,106 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113137,809,499 - 137,865,383 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213147,430,086 - 147,483,561 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PARP14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12258,135,092 - 58,185,988 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2258,134,973 - 58,185,521 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041108,163,757 - 108,215,859 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000002614   ⟹   ENSHGLP00000002562
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624912969,236 - 1,023,564 (+)Ensembl
RefSeq Acc Id: XM_013068813   ⟹   XP_012924267
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624912969,144 - 1,022,506 (+)NCBI
RefSeq Acc Id: XM_013068814   ⟹   XP_012924268
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624912969,144 - 1,020,048 (+)NCBI
Protein Sequences
Protein RefSeqs XP_012924267 (Get FASTA)   NCBI Sequence Viewer  
  XP_012924268 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002562
GenBank Protein JAN98573 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_012924267   ⟸   XM_013068813
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ET88 (UniProtKB/TrEMBL),   G5AV98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012924268   ⟸   XM_013068814
- Peptide Label: isoform X2
- UniProtKB: G5AV98 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000002562   ⟸   ENSHGLT00000002614


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001930 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000002614 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
  3.30.720.50 UniProtKB/TrEMBL
  3.40.220.10 UniProtKB/TrEMBL
  3.90.228.10 UniProtKB/TrEMBL
InterPro Macro_dom UniProtKB/TrEMBL
  Macro_dom-like UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  Poly(ADP-ribose)pol_cat_dom UniProtKB/TrEMBL
  WWE-dom UniProtKB/TrEMBL
  WWE_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101698647 UniProtKB/TrEMBL
NCBI Gene Parp14 ENTREZGENE
PANTHER PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 UniProtKB/TrEMBL
Pfam Macro UniProtKB/TrEMBL
  PARP UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
PROSITE MACRO UniProtKB/TrEMBL
  PARP_CATALYTIC UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
SMART A1pp UniProtKB/TrEMBL
Superfamily-SCOP ADP-ribosylation UniProtKB/TrEMBL
  SSF117839 UniProtKB/TrEMBL
  SSF52949 UniProtKB/TrEMBL
UniProt A0A0N8ET88 ENTREZGENE, UniProtKB/TrEMBL
  G5AV98 ENTREZGENE, UniProtKB/TrEMBL