Mkks (MKKS centrosomal shuttling protein) - Rat Genome Database

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Gene: Mkks (MKKS centrosomal shuttling protein) Heterocephalus glaber
Analyze
Symbol: Mkks
Name: MKKS centrosomal shuttling protein (Ensembl:McKusick-Kaufman syndrome)
RGD ID: 18915197
Description: ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN artery smooth muscle contraction (ortholog); brain morphogenesis (ortholog); cartilage development (ortholog); ASSOCIATED WITH ALAGILLE SYNDROME 1 (ortholog); Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 1 (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); motile cilium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: McKusick-Kaufman syndrome; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474111,425,368 - 11,435,706 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474111,323,935 - 11,447,669 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mkks
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474111,425,368 - 11,435,706 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474111,323,935 - 11,447,669 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MKKS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382010,401,009 - 10,434,222 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2010,401,009 - 10,434,222 (-)EnsemblGRCh38hg38GRCh38
GRCh372010,381,657 - 10,414,870 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362010,333,832 - 10,362,866 (-)NCBINCBI36Build 36hg18NCBI36
Build 342010,333,832 - 10,362,866NCBI
Celera2010,455,827 - 10,484,860 (-)NCBICelera
Cytogenetic Map20p12.2NCBI
HuRef2010,337,201 - 10,366,656 (-)NCBIHuRef
CHM1_12010,385,992 - 10,415,443 (-)NCBICHM1_1
T2T-CHM13v2.02010,444,020 - 10,477,226 (-)NCBIT2T-CHM13v2.0
Mkks
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392136,715,700 - 136,733,422 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2136,715,700 - 136,733,309 (-)EnsemblGRCm39 Ensembl
GRCm382136,873,780 - 136,891,406 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2136,873,780 - 136,891,389 (-)EnsemblGRCm38mm10GRCm38
MGSCv372136,699,516 - 136,717,142 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362136,565,505 - 136,582,619 (-)NCBIMGSCv36mm8
Celera2138,065,345 - 138,082,981 (-)NCBICelera
Cytogenetic Map2F3NCBI
cM Map267.64NCBI
Mkks
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83144,654,563 - 144,672,831 (-)NCBIGRCr8
mRatBN7.23124,201,877 - 124,221,142 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3124,201,877 - 124,220,162 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3128,088,345 - 128,106,518 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03136,665,331 - 136,683,502 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03134,350,175 - 134,368,340 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03129,866,542 - 129,885,213 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3129,866,545 - 129,884,810 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03136,347,547 - 136,365,815 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43124,975,099 - 124,993,345 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13124,880,674 - 124,898,918 (-)NCBI
Celera3122,920,784 - 122,939,041 (-)NCBICelera
Cytogenetic Map3q36NCBI
Mkks
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541520,292,663 - 20,300,797 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541520,292,311 - 20,315,850 (-)NCBIChiLan1.0ChiLan1.0
MKKS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22111,276,201 - 11,284,953 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12011,268,851 - 11,281,370 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02010,346,252 - 10,380,180 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12010,351,246 - 10,380,503 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2010,351,309 - 10,366,863 (-)Ensemblpanpan1.1panPan2
MKKS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12411,887,504 - 11,914,055 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2411,898,236 - 11,913,740 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2411,706,600 - 11,733,151 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02412,298,493 - 12,325,072 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2412,298,503 - 12,325,070 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12411,905,962 - 11,932,517 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02412,005,123 - 12,031,666 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02412,348,068 - 12,374,624 (+)NCBIUU_Cfam_GSD_1.0
Mkks
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640160,657,713 - 160,683,085 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364859,088,963 - 9,115,175 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364859,089,118 - 9,114,396 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MKKS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1719,341,636 - 19,362,871 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11719,341,024 - 19,363,007 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21721,817,124 - 21,839,355 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MKKS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1227,728,295 - 27,757,569 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl227,736,537 - 27,757,237 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607116,818,364 - 16,851,748 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004840819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004840820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004840821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004840822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021255069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002393474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002393475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002393476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002393477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01019152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01019161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01001151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000019061   ⟹   ENSHGLP00000018872
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474111,425,368 - 11,435,706 (-)Ensembl
RefSeq Acc Id: XM_004840819   ⟹   XP_004840876
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,422,298 - 11,447,669 (-)NCBI
RefSeq Acc Id: XM_004840820   ⟹   XP_004840877
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,422,298 - 11,447,587 (-)NCBI
RefSeq Acc Id: XM_004840821   ⟹   XP_004840878
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,422,298 - 11,447,669 (-)NCBI
RefSeq Acc Id: XM_004840822   ⟹   XP_004840879
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,422,298 - 11,447,669 (-)NCBI
RefSeq Acc Id: XM_021255069   ⟹   XP_021110728
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,422,298 - 11,447,542 (-)NCBI
RefSeq Acc Id: XR_002393474
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,418,798 - 11,447,669 (-)NCBI
RefSeq Acc Id: XR_002393475
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,323,935 - 11,447,669 (-)NCBI
RefSeq Acc Id: XR_002393476
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,411,911 - 11,447,669 (-)NCBI
RefSeq Acc Id: XR_002393477
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474111,418,798 - 11,447,669 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004840876 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840877 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840878 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840879 (Get FASTA)   NCBI Sequence Viewer  
  XP_021110728 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018872
GenBank Protein JAO02482 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004840878   ⟸   XM_004840821
- Peptide Label: isoform X2
- UniProtKB: G5B2B2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840879   ⟸   XM_004840822
- Peptide Label: isoform X3
- UniProtKB: G5B2B2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840876   ⟸   XM_004840819
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JEE9 (UniProtKB/TrEMBL),   G5B2B2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840877   ⟸   XM_004840820
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JEE9 (UniProtKB/TrEMBL),   G5B2B2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110728   ⟸   XM_021255069
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JEE9 (UniProtKB/TrEMBL),   G5B2B2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000018872   ⟸   ENSHGLT00000019061


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013526 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019061 ENTREZGENE
Gene3D-CATH 1.10.560.10 UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/TrEMBL
InterPro Cpn60/TCP-1 UniProtKB/TrEMBL
  GroEL-like_apical_dom_sf UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/TrEMBL
  MKKS UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/TrEMBL
KEGG Report hgl:101699409 UniProtKB/TrEMBL
NCBI Gene Mkks ENTREZGENE
PANTHER PTHR46787 UniProtKB/TrEMBL
  SYNDROMES PUTATIVE CHAPERONIN-RELATED UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48592 UniProtKB/TrEMBL
  SSF52029 UniProtKB/TrEMBL
UniProt A0A0P6JEE9 ENTREZGENE, UniProtKB/TrEMBL
  G5B2B2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-23 Mkks  MKKS centrosomal shuttling protein  Mkks  McKusick-Kaufman syndrome  Symbol and/or name change 5135510 APPROVED