Mtap (methylthioadenosine phosphorylase) - Rat Genome Database

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Gene: Mtap (methylthioadenosine phosphorylase) Heterocephalus glaber
Analyze
Symbol: Mtap
Name: methylthioadenosine phosphorylase
RGD ID: 18915142
Description: ENCODES a protein that exhibits S-methyl-5-thioadenosine phosphorylase activity (ortholog); INVOLVED IN methylation (ortholog); nicotinamide riboside catabolic process (ortholog); response to testosterone (ortholog); PARTICIPATES IN glycine N-methyltransferase deficiency pathway; homocystinuria pathway; hypermethioninemia pathway; ASSOCIATED WITH biliary tract benign neoplasm (ortholog); common bile duct neoplasm (ortholog); diaphyseal medullary stenosis with malignant fibrous histiocytoma (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: S-methyl-5'-thioadenosine phosphorylase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473625,778,240 - 25,826,530 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473625,778,191 - 25,826,945 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mtap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473625,778,240 - 25,826,530 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473625,778,191 - 25,826,945 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MTAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38921,802,636 - 21,941,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl921,802,636 - 21,937,651 (+)EnsemblGRCh38hg38GRCh38
GRCh37921,802,635 - 21,941,114 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36921,792,635 - 21,855,970 (+)NCBINCBI36Build 36hg18NCBI36
Build 34921,792,634 - 21,855,967NCBI
Celera921,740,998 - 21,804,334 (+)NCBICelera
Cytogenetic Map9p21.3NCBI
HuRef921,765,963 - 21,829,332 (+)NCBIHuRef
CHM1_1921,802,515 - 21,865,858 (+)NCBICHM1_1
T2T-CHM13v2.0921,816,863 - 21,955,417 (+)NCBIT2T-CHM13v2.0
Mtap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39489,055,607 - 89,099,327 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl489,055,359 - 89,099,318 (+)EnsemblGRCm39 Ensembl
GRCm38489,137,370 - 89,181,090 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl489,137,122 - 89,181,081 (+)EnsemblGRCm38mm10GRCm38
MGSCv37488,783,274 - 88,826,994 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36488,608,657 - 88,652,314 (+)NCBIMGSCv36mm8
Celera487,620,095 - 87,663,899 (+)NCBICelera
Cytogenetic Map4C4NCBI
cM Map442.15NCBI
Mtap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85108,990,270 - 109,036,494 (+)NCBIGRCr8
mRatBN7.25103,874,460 - 103,920,684 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5103,873,020 - 103,939,406 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5106,308,258 - 106,354,482 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05108,037,874 - 108,084,086 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05108,118,643 - 108,164,834 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05107,711,077 - 107,777,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5107,711,077 - 107,777,530 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05111,679,661 - 111,746,208 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45108,788,725 - 108,861,905 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15108,793,950 - 108,867,131 (+)NCBI
Celera5102,587,860 - 102,654,739 (+)NCBICelera
Cytogenetic Map5q32NCBI
Mtap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547212,390,032 - 12,439,206 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547212,391,399 - 12,439,221 (-)NCBIChiLan1.0ChiLan1.0
MTAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211102,620,519 - 102,756,196 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19102,623,086 - 102,762,138 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0921,637,543 - 21,769,698 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1922,253,357 - 22,316,883 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl922,266,376 - 22,382,218 (+)Ensemblpanpan1.1panPan2
MTAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11141,148,389 - 41,200,635 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1141,148,404 - 41,264,504 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1139,820,541 - 39,872,745 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01142,090,758 - 42,142,952 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1142,090,124 - 42,142,944 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11140,760,953 - 40,813,082 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01140,648,752 - 40,701,001 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01141,262,101 - 41,314,256 (+)NCBIUU_Cfam_GSD_1.0
Mtap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947155,762,052 - 155,800,008 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366523,431,171 - 3,472,071 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366523,431,588 - 3,468,770 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1200,882,956 - 200,934,445 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11200,882,954 - 200,934,389 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,075,795 - 224,126,822 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11584,196,548 - 84,198,357 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1257,997,427 - 58,050,241 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604157,778,455 - 57,780,270 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000009312   ⟹   ENSHGLP00000009212
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473625,778,240 - 25,826,530 (+)Ensembl
RefSeq Acc Id: XM_004838350   ⟹   XP_004838407
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473625,778,191 - 25,826,945 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004838407 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000009212
  ENSHGLP00100001827
GenBank Protein JAO00169 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004838407   ⟸   XM_004838350
- UniProtKB: A0A0P6J985 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000009212   ⟸   ENSHGLT00000009312


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006616 Ensembl, ENTREZGENE
  ENSHGLG00100001423 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000009312 ENTREZGENE
  ENSHGLT00100001868 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1580 UniProtKB/TrEMBL
InterPro MTAP UniProtKB/TrEMBL
  Nucleoside_phosphorylase_d UniProtKB/TrEMBL
  Nucleoside_phosphorylase_sf UniProtKB/TrEMBL
  Purine_phosphorylase-2_CS UniProtKB/TrEMBL
KEGG Report hgl:101700706 UniProtKB/TrEMBL
NCBI Gene Mtap ENTREZGENE
PANTHER PTHR42679 UniProtKB/TrEMBL
  S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE UniProtKB/TrEMBL
Pfam PNP_UDP_1 UniProtKB/TrEMBL
PROSITE PNP_MTAP_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53167 UniProtKB/TrEMBL
UniProt A0A0P6J985 ENTREZGENE, UniProtKB/TrEMBL