Txnl4a (thioredoxin like 4A) - Rat Genome Database

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Gene: Txnl4a (thioredoxin like 4A) Heterocephalus glaber
Analyze
Symbol: Txnl4a
Name: thioredoxin like 4A
RGD ID: 18915047
Description: INVOLVED IN mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Burn-McKeown syndrome (ortholog); chromosome 18q deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: thioredoxin-like protein 4A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624806367,286 - 385,946 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624806367,668 - 385,946 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Txnl4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624806367,286 - 385,946 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624806367,668 - 385,946 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TXNL4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381879,970,813 - 80,033,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1879,970,813 - 80,033,949 (-)EnsemblGRCh38hg38GRCh38
GRCh371877,730,813 - 77,793,936 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361875,833,855 - 75,849,520 (-)NCBINCBI36Build 36hg18NCBI36
Build 341875,833,855 - 75,849,520NCBI
Celera1874,505,339 - 74,521,004 (-)NCBICelera
Cytogenetic Map18q23NCBI
HuRef1874,354,321 - 74,369,986 (-)NCBIHuRef
CHM1_11877,728,173 - 77,743,835 (-)NCBICHM1_1
T2T-CHM13v2.01880,247,334 - 80,310,473 (-)NCBIT2T-CHM13v2.0
Txnl4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391880,250,041 - 80,269,066 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1880,249,980 - 80,255,956 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl1880,250,010 - 80,269,070 (+)EnsemblGRCm39 Ensembl
GRCm381880,206,826 - 80,225,851 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1880,206,795 - 80,225,855 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1880,206,765 - 80,212,741 (+)EnsemblGRCm38mm10GRCm38
MGSCv371880,403,537 - 80,422,590 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361880,368,858 - 80,387,910 (+)NCBIMGSCv36mm8
Celera1881,326,193 - 81,346,625 (+)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1853.34NCBI
Txnl4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81875,934,085 - 75,949,873 (+)NCBIGRCr8
mRatBN7.21873,659,107 - 73,674,893 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1873,659,107 - 73,674,893 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1875,760,800 - 75,776,460 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01876,430,148 - 76,445,808 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01874,275,535 - 74,291,375 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01876,725,221 - 76,740,673 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1876,725,247 - 76,740,688 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01872,067,372 - 72,082,799 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1872,321,825 - 72,336,942 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
Txnl4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540263,153,052 - 63,166,199 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540263,153,274 - 63,166,208 (+)NCBIChiLan1.0ChiLan1.0
TXNL4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21797,606,821 - 97,670,745 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11883,302,072 - 83,363,366 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01873,618,302 - 73,679,603 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11876,937,460 - 76,952,428 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1876,937,460 - 76,952,428 (-)Ensemblpanpan1.1panPan2
TXNL4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11722,223 - 735,253 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1722,293 - 735,258 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha11,724,232 - 1,737,274 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01520,112 - 533,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1520,550 - 533,021 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11573,166 - 586,068 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01518,510 - 531,414 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01689,716 - 702,621 (+)NCBIUU_Cfam_GSD_1.0
Txnl4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494414,899,459 - 14,912,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936616220,274 - 234,870 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936616220,255 - 232,042 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TXNL4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6127,974,543 - 127,991,177 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16127,975,164 - 127,991,112 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21310,124,483 - 310,140,432 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TXNL4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118270,392 - 286,243 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18270,938 - 285,966 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606026,031,195 - 26,046,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000003178   ⟹   ENSHGLP00000003123
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624806367,286 - 385,946 (+)Ensembl
RefSeq Acc Id: XM_004861905   ⟹   XP_004861962
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624806367,670 - 385,946 (+)NCBI
RefSeq Acc Id: XM_004861906   ⟹   XP_004861963
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624806367,670 - 385,946 (+)NCBI
RefSeq Acc Id: XM_013078560   ⟹   XP_012934014
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624806367,691 - 385,946 (+)NCBI
RefSeq Acc Id: XM_021242128   ⟹   XP_021097787
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624806367,690 - 385,946 (+)NCBI
RefSeq Acc Id: XR_002388483
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624806367,668 - 385,671 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004861962 (Get FASTA)   NCBI Sequence Viewer  
  XP_004861963 (Get FASTA)   NCBI Sequence Viewer  
  XP_012934014 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097787 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003123
GenBank Protein JAN97850 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004861962   ⟸   XM_004861905
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J5I6 (UniProtKB/TrEMBL),   G5AVW4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861963   ⟸   XM_004861906
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021097787   ⟸   XM_021242128
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J5I6 (UniProtKB/TrEMBL),   G5AVW4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012934014   ⟸   XM_013078560
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000003123   ⟸   ENSHGLT00000003178


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002332 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000003178 ENTREZGENE
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro Dim1 UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
KEGG Report hgl:101724854 UniProtKB/TrEMBL
NCBI Gene Txnl4a ENTREZGENE
PANTHER PTHR12052 UniProtKB/TrEMBL
  THIOREDOXIN-LIKE PROTEIN 4A UniProtKB/TrEMBL
Pfam DIM1 UniProtKB/TrEMBL
PIRSF mRNA_splic_U5 UniProtKB/TrEMBL
SMART DIM1 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A0P6J5I6 ENTREZGENE, UniProtKB/TrEMBL
  G5AVW4 ENTREZGENE, UniProtKB/TrEMBL